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排序方式: 共有362条查询结果,搜索用时 15 毫秒
1.
A Oyane M Kasahara N Ichinose Y Yokoyama M Uchida A Ito 《武汉理工大学学报(材料科学英文版)》2005,20(B12):220-222
A synthetic polymer with a laminin-apatite composite layer on its surface would be useful as a percutaneous device. The preparation of such a composite was attempted in the present study using poly( ethylene terephthalate ) (PET) and polyethylene (PE) as the synthetic polymer. PET and PE plates and those pretreated with an oxygen plasma were alternately dipped in calcium and phosphate ion solutions, and then immersed in a metastable calcium phosphate solution supplemented with laminin ( LCP solution ). The PET and PE plates pretreated with an oxygen plasma formed a uniform and continuous layer of a laminin-apatite composite on their surfaces. In contrast, the PET and PE plates that had not been pretreated with an oxygen plasma did not form a continuous layer of a laminin-apatite composite on their surfaces. The hydrophilic functional groups on the PET and PE surfaces introduced by the plasma treatment were responsible for the successful laminin-apatite coruposite coating. 相似文献
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采用人工合成高纯度的羟基磷灰石粉末,喷涂在具有注册证的钛合金和钴铬钼合金人工关节上。通过生物学基础检测、动物实验和临床试用,证明所制作的各种羟基磷灰石涂层人工关节,能诱发骨质生长,起生物固定作用,对治疗丧失功能的骨胳效果甚佳。 相似文献
4.
溶胶-凝胶生物玻璃多孔材料显微结构和生物活性的扫描电镜及红外光谱分析 总被引:13,自引:0,他引:13
本文利用溶胶.凝胶法制备了CaO-P2O5-SiO,系统生物活性玻璃,并以其为原料制备了用于骨修复及骨组织工程支架的块状生物活性材料。利用体外实验方法(invitro)结合x射线衍射(XRD)、扫描电子显微镜(SEM)和傅立叶变换红外光谱分析(FTIR)技术对不同烧结工艺制备的材料结构、晶相和生物活性的影响进行了分析研究。研究表明,经800℃和1100℃烧结5min的两种材料均有硅磷酸钙Ca5(PO4)2SjO4微晶相析出。烧结温度越高,析出微晶相的体积比例越大,材料的生物活性则越低。在模拟生理溶液中碳酸羟基磷灰石(HCA)只在烧结体中的玻璃颗粒表面形成,而在其硅磷酸钙Ca5(PO4)2SiO4微晶相表面未发现HCA形成。 相似文献
5.
对迁安地区磁选精矿粉添加磷石粉和B2O3,生产二元碱率为2.0左右的高碱度烧结矿,在实验室和现场进行了试验。结果表明:加入少量磷灰石粉或硼即可完全抑制烧结矿冷却过程中的自然粉化现象;MgO含量对烧结矿质量影响明显;烧结矿的冶金性能良好。 相似文献
6.
应用磷灰石裂变径迹研究大民屯凹陷的古地温 总被引:4,自引:0,他引:4
为深刻认识辽河盆地古地温特征,利用裂变径迹分析方法,对大民屯凹陷钻井岩心中19块磷灰石样品的裂变径迹年龄和长度做了测试。结果表明,随井深增加,径迹年龄和平均径迹长度有减少、变短的显著趋势,ES3^4地层磷灰石裂变径迹表观年龄比地层年龄年轻得多,说明沉积后曾长时间处于退火带中,退火带古地温为74~130℃,有效加热时间为4l~45Ma,2300~4000m深度地层处于退火过渡带。将径迹长度分布特征与地史、热史模拟结果相结合,认为该区在ES4段末经历一次短时间迅速增温后,ES3^1亚段存在一个区域抬升降温的热事件过程,其后地层稳定下降,沉降幅度小、沉积物较薄,温度增加缓慢,古地温梯度高于今地温梯度,对生、排烃较为有利。 相似文献
7.
Min?-Ho?LeeEmail author Dong?-Joo?Yoon Dae?-Hee?Won Tae?-Sung?Bae Fumio?Watari 《Metals and Materials International》2003,9(1):35-42
In the present study, commercial pure Ti and Ti-6Al-4V alloy specimens with and without alkali and heat treatments were implanted
in the abdominal connective tissue of mice. Conventional stainless steel 316L was also implanted for comparison. After three
months, their biocompatibility was evaluated byin vitro andin vivo experiments. Surface structural changes of specimens due to the alkali treatment and soaking in Hank’s solution were analyzed
by XRD, SEM, XPS and AES. An apatite layer, which accelerates the connection with bone, was formed more easily on the alkali
treated specimens than the non-treated specimens. The number of macrophages, which is known to increase as the inflammatory
reaction proceeds, was much lower for the alkali and heat treated specimens than for the others. The average thickness of
the fibrous capsule formed around the implant was much thinner for the alkali and heat treated specimens than for the others. 相似文献
8.
赣西地区浒坑钨矿是我国华南钨、锡、铜多金属成矿区与中生代岩浆活动密切相关的典型矿床之一。对浒坑钨矿床中与成矿有关的白云母花岗岩开展了锆石U-Pb定年、磷灰石和锆石原位微量元素研究,结果表明:赋矿白云母花岗岩的成岩时代为(152.3±1.73)Ma;磷灰石具有特殊的“M”型REE球粒陨石标准化配分模式,富F和Mn,贫Cl和Mg;锆石具有高Th/U比值,REE球粒陨石标准化配分模式亏损LREE、富集HREE。锆石微量元素(Ce、U和Ti)温度计和氧逸度计结果表明,锆石形成于岩浆早期高温(800 ℃)和低氧逸度条件下。研究认为,浒坑赋矿花岗岩在演化初期经历了强烈的矿物结晶分异,矿床的形成可能与还原性高分异岩浆演化相关。 相似文献
9.
The apatite-coated chitosan microspheres were fabricated by incubating chitosan in five times simulated body fluid. The apatite deposited on the microspheres was similar to natural bone mineral, as demonstrated by scanning electron microscopy, X-ray diffraction spectra and Fourier transformed-infrared spectroscopy analyses. Rat bone marrow-derived mesenchymal stem cells (BMSCs) were seeded on apatite- coated microspheres to investigate the effect of this scaffold on cell proliferation and differentiation. BMSCs seeded on uncoated microspheres were served as a control. In vivo experiment was evaluated by transplanting the microspheres loaded with or without BMSCs in 5-mm cranial defects of Wistar rats. Bone regeneration was investigated via micro-CT and histological analysis. It was found that apatite-coated chitosan microspheres could significantly promote the proliferation and alkaline phosphatase activity of BMSCs compared with uncoated microspheres. Histological slices and Micro-CT images at 8 weeks revealed much better regeneration of bone in the apatite-coated microspheres loaded with BMSCs than the control. In addition, the defect filled with pure microspheres induced little new bone formation. Our findings suggest that the apatite-coated chitosan microspheres scaffold is a promising carrier of stem cells for cranial bone tissue engineering. 相似文献
10.
The bioactivity of mica/apatite glass ceramic composites, including the in vitro behavior in simulated body fluid and the histological appearance of the interface between the mica/apatite glass ceramics and the rabbit mandible defect in vivo under a dynamic condition. The results show that biological apatite layer forms on the surface of the mica/apatite glass ceramics after l d of immersion in the simulated body fluid, and becomes dense after 14 d. In vivo tests indicate that bone formation occurs after implantation for 14 d, and strong bonding of bone to the implant occurs after 42 d. No aseptic loosening occurs during 42 d of implantation. The finding shows that mica/apatite glass ceramics have good bioactivity and osteoconductivity for constructing bone graft, and can be promising for biomedical application. 相似文献