气相色谱-质谱法分析含羞草挥发油的化学成分

采用常规水蒸气蒸馏法提取含羞草中的挥发油，并用气相色谱-质谱法分析其化学成分。分离出41个峰，鉴定出34种化学成分，占总峰面积的89.01 %。含羞草挥发油中主要成分为N,N-二苯基-肼酰胺、邻苯二甲酸二异丁酯、邻苯二甲酸丁基-2-甲基丙基酯、十九烷、1H-吲哚-3-乙醇、二十四烷、2,4-二（1-苯乙基）苯酚、二十六烷、二十七烷等。     

探空站历年各方位的仰角最低值统计程序

在L波段测风雷达拟建过程中，各探空站都要做一项工作量巨大且繁琐的统计工作。为此本人利用业余时间编写了一个自动统计程序，它能自动进行统计计算，节省人力和时间。本程序在本省、北京、上海等一些探空站使用过，反映良好。本文将介绍其使用方法。     

MoSi2/不锈钢的梯度连接及其接头组织

采用放电等离子烧结技术和有限元分析设计的MoSi2/316L梯度材料作为过渡层连接MoSi2与316L不锈钢,研究了各层及界面组织.结果表明:MoSi2与梯度过渡层材料间热膨胀系数的有效匹配,可防止低韧性MoSi2由连接温度(1 200 ℃)冷却时产生的残余应力而引起的开裂;使用9层MoSi2/316L梯度材料过渡层体系可获得一种组织致密且均匀的接头;MoSi2/316L不锈钢梯度过渡层在宏观上呈现明显的梯度,微观上则表现出成分连续变化,且各层成分分布均匀.     

中草药对蛹虫草液体深层发酵的影响

运用均匀性试验,正交试验和Ｄ－最优设计等方法,以菌丝体干重为指标,对蛹昌菌进行液体发酵获得了最佳添加中草药培养基的配方,确定了最适培养条件。     

Mappings of Bounded Φ-Variation with Arbitrary Function Φ

We develop the general theory of mappings of bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation in the sense of L. C. Young that are defined on a subset of the real line and take values in metric or normed spaces. We single out the characterizing properties for these mappings, prove the structural theorem for them, and study their continuity properties. We obtain the existence of a geodesic path of bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation between two points of a compact set with certain regularity of its modulus of continuity. The classical Helly selection principle from the theory of functions of bounded variation is generalized for mappings of bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation. Under natural restrictions on the function L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">, we show that the space of all normed space-valued mappings under consideration can be endowed with a metric. Finally, we consider the problem of existence of selections of a continuous set-valued mapping Fof bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation with respect to the Hausdorff distance. We show that if L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">L8G907J810/xxlarge8242.gif" alt="prime" align="BASELINE" BORDER="0">(0) is finite> 0, then Fhas a continuous selection of bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation; if L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">L8G907J810/xxlarge8242.gif" alt="prime" align="BASELINE" BORDER="0">(0) = L8G907J810/xxlarge8734.gif" alt="infin" align="MIDDLE" BORDER="0">, then Fis a constant mapping; and if L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">L8G907J810/xxlarge8242.gif" alt="prime" align="BASELINE" BORDER="0">(0) = 0, then, under additional assumptions on L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">, we give examples of mappings Fwith no continuous selection and with no selection of bounded L8G907J810/xxlarge934.gif" alt="PHgr" align="BASELINE" BORDER="0">-variation.     

Tumor Microenvironment‐Responsive Dual Drug Dimer‐Loaded PEGylated Bilirubin Nanoparticles for Improved Drug Delivery and Enhanced Immune‐Chemotherapy of Breast Cancer

The application of combinational therapy makes up for the limitation of monotherapy and achieves superior treatment against cancer. However, the combinational therapy remains restricted by the poor tumor‐specific delivery and the abscopal effect. Herein, reactive oxygen species (ROS)‐responsive PEGylated bilirubin nanoparticles (BRNPs) are developed to encapsulate two glutathione‐activatable drugs, including dimer‐7‐ethyl‐10‐hydroxycamptothecin (d‐SN38) and dimer‐lonidamine (d‐LND). Dimerization of the drugs significantly increases the drug loading capacity and the encapsulation efficiency of nanoparticles. With the assistance of iRGD peptide (cRGDKGPDC), the cellular uptake of BRNPs is more than double when compared with the control. In response to high levels of intracellular ROS, d‐SN38 and d‐LND are rapidly released from nanoparticles (SL@BRNPs). Furthermore, the pharmacodynamic experiments verify combining SL@BRNPs with anti‐PD‐L1 antibody greatly inhibits the primary tumor of breast cancer, improves CD8+ T cells levels, and CD8+ T cells/Tregs ratios in the tumor. Additionally, it shows high immune memory effect and can prevent the growth of lung metastasis. Taken together, the strategy pioneers a new way for the rational design of nanoassemblies through the combination of activatable drug dimers and stimuli‐responsive drug release, and a successful application of novel drug delivery systems in combination with the immune checkpoint blockade antibody.     

基于L2TP VPDN技术实现空管核心业务的传输

目前空管核心业务包括雷达、VHF语音、自动转报等,这些核心业务以地面传输链路为主,缺乏有效的无线传输方式做保障,随着运营商4G网络覆盖的普及,稳定性能的提升,可以利用运营商的4G网络传输空管核心业务。本文结合VPDN(Virtual Private Dial-up Networks)技术在互联网上采用L2TP(Layer 2 Tunnel Protocol)建立私有专用通道的特点,设计了一套利用运营商的4g网络传输空管核心业务的方案,以解决缺乏无线传输方式做备份或者部分偏远台站,没有有线链路传输业务的问题。     

Regional flood frequency analysis in the central‐western river basins of Argentina

Knowing the probability of occurrence of a flood event is an important issue for water resources planning. At‐site probability models require a long extension of hydrological data for robust estimation of low‐frequency events. As the mean record length of 25 gauge stations in western river basins of Argentina is 49 years (until 2010), regional models are an interesting tool to determine mountain rivers system dynamics. This study aims to estimate low‐frequency quantiles of annual maximum flow in Argentinean western river basins (28°S–37°S) applying regional frequency analysis based on the L‐moments method. Besides, mean annual maximum flow of 75 gauge stations (22°S–52°S) was analysed. First, an exploratory data analysis was performed; normality, independence, and randomness were accepted in the 27%, 87%, and 91% of cases, respectively. Increasing trends in annual maximum flows in the north‐western and central‐western rivers of Argentina were detected, whereas decreasing trends in annual maximum flow in the Patagonian Andes were identified. Base on at‐site characteristics and at‐site statistics, a homogeneous region of 12 stations with a record period of 568 years was formed. General extreme value was the most appropriate distribution for this homogeneous study region. Estimation accuracy using Monte Carlo simulations was performed. The error bounds were set at 90%, the mean square error was 9.23%, and the relative bias was 1.6%. The regional method performed better than the at‐site estimation.     

非高斯列维噪声激励下非线性系统的Lyapunov指数

研究了非高斯列维噪声作用下非线性系统的渐近线性化方法和Lyapunov指数.利用渐近线性化方法将非线性系统线性化,通过系统的响应轨迹验证了该方法的有效性.通过广义的伊藤法则公式,推导出了列维噪声驱动下Lyapunov指数的一般表达式.给出当参数变化时,非线性系统的随机稳定性分析.     

超混沌吕系统的滞后投影同步与参数识别

研究了超混沌吕系统的滞后投影同步与系统参数识别.在响应系统中加入适当的非线性控制器,利用Lyapunov稳定性方法和Barbalat引理进行理论分析证明,实现了驱动响应系统之间所有变量的全局滞后投影同步,并能够对超吕系统的未知参数进行识别.最后通过数值仿真对本文中提出的理论方法的正确性及可行性进行验证.