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Over the course of the last two years, ScanLAB Projects have explored various fragments of the natural and man-made world through the eyes of their forensic measuring machine. From surface mapping of Arctic ice floes in the Fram Strait (gateway to the Arctic) to the documentation of torture and detention sites in the Balkans, via the accidental editing of a Richard Long sculpture, to purposeful acts of detail theft from Foster and Wren. Here, Matthew Shaw and William Trossell discuss the capture, analysis and refabrication of their digital architectural doppelgängers. 相似文献
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目的观察注射用重组人B淋巴细胞刺激因子受体-抗体融合蛋白(RCT-18)对大鼠生育力及早期胚胎发育的毒性作用。方法将SD大鼠随机分为4组,分别经皮下注射RCT-18 129、37、11 mg/(kg.d)和0.9%NaCl注射液,每2 d给药1次。雄鼠连续给药5周、雌鼠连续给药2周后,按雌雄1∶1的比例合笼交配,合笼期为2周,计算交配率。雄鼠继续给药至交配成功,雌鼠继续给药至妊娠第6天。实验过程中观察动物的一般反应、体重及摄食量变化。确定雌鼠受精后处死雄鼠,解剖检查睾丸和附睾等生殖器官。于妊娠第15天解剖孕鼠,综合评价妊娠及胚胎形成和早期发育等情况。结果 RCT-18高、中、低剂量组雌性和雄性大鼠均未出现明显的母体毒性反应。各组大鼠各脏器均未见肉眼可见的异常。各剂量RCT-18对大鼠的交配率、妊娠率、生殖系统脏器重量和系数以及早期胚胎发育均无明显影响。结论RCT-18对SD大鼠的生育力及早期胚胎发育无明显毒性作用。 相似文献
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Quantitative phase imaging (QPI) is a powerful tool for label-free visualisation of living cells. Here, we compare two QPI microscopes – the Telight Q-Phase microscope and the Nanolive 3D Cell Explorer-fluo microscope. Both systems provide unbiased information about cell morphology, such as individual cell dry mass, perimeter and area. The Q-Phase microscope uses artefact-free, coherence-controlled holographic imaging technology to visualise cells in real time with minimal phototoxicity. The 3D Cell Explorer-fluo employs laser-based holotomography to reconstruct 3D images of living cells, visualising their internal structures and dynamics. Here, we analysed the strengths and limitations of both microscopes when examining two morphologically distinct cell lines – the cuboidal epithelial MDCK cells which form multicellular clusters and solitary growing Rat2 fibroblasts. We focus mainly on the ability of the devices to generate images suitable for single-cell segmentation by the built-in software, and we discuss the segmentation results and quantitative data generated from the segmented images. We show that both microscopes offer slightly different advantages, and the choice between them depends on the specific requirements and goals of the user. 相似文献
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It is tried to compare the effects of sample preparation on shapes and sizes of ribosomes deposited on mica.The apparent sizes of ribosomes in the atomic force microscopy (AFM) images are about 60nm in most cases,The height appears to be indifferent to the sample preparation method and image conditions.It is found that the dehydration may greatly affect the topography of ribosomes.The volumes of ribosomes are estimated after considering the convolution effects of AFM tip on the appearance of ribosomes. 相似文献
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本文报道用~(144)Ce(No_3)_3沾染不同深度的大鼠伤口所致各组织器官中~(144)Ce 的沉积率及其动态变化和实验治疗的研究结果。实验结果表明,内脏~(144)Ce 的沉积率随伤口的深度增加而增高,骨、肝等脏器的沉积率的对数与致伤后时间的对数间可拟合成抛物线型回归方程;伤口局部~(144)Ce 的残留率随致伤后时间的对数的变化可拟合成对数回归方程。伤口沾染~(144)Ce(No_3)_3的实验治疗以络合剂局部注射效果较好。 相似文献
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A mathematical physiological flow model is described for the distribution and elimination of adriamycin in the rat. The model includes the volume or mass of, and blood flow to the following tissues: heart, plasma, muscle, skin, kidney, bone marrow, gut, liver and bile. A compartment is also included for tight or almost irreversible binding which occurs with this drug. The program was written in FORTRAN to compute the concentration of drug in each tissue as a function of time after bolus injection or short term infusion. The computed data is printed on a line printer and recorded on disk for use in a SAS program GPLOT to obtain precision plots. 相似文献