Isolation and preliminary characterization of Pichia pinus mutants insensitive to glucose repression

A new method for the isolation of glucose repression-insensitive mutants in the methylotrophic yeast Pichia pinus was developed. The method is based on screening of small suspension samples derived from 2-deoxyglucose-resistant colonies for alcohol oxidase activity. Alcohol oxidase activity was evaluated by determination of formaldehyde excreted by cells. Mutants with glucose non-repressible alcohol oxidase and catalase synthesis were obtained. All mutants grew poorly on D -xylose compared to the wild type, whereas growth on L -arabinose was similar to the wild type. Changes in the glucose transport system were suggested to be responsible for altered growth characteristics and defective glucose repression.     

Extraction of penicillin G from simulated media by an emulsion liquid membrane process

The extraction of penicillin G from simulated media was performed by water/oil/water (w/o/w) emulsion liquid membranes (ELMs) and studied under various operational conditions in a batch system. The degree of extraction achieved was between 80% and 95% under specific conditions. A concentration of greater than nine times the initial concentration of penicillin G in the external phase was obtained in the internal phase. The pH of the internal aqueous solution, containing a basic salt, was theoretically calculated on the basis of the amount of penicillin G transported into the internal phase. The calculated results agreed with the experimental data well and were used to select a suitable type and concentration of a basic salt in the internal phase to give a pH within the range 5 to 8 where penicillin G was stable after the termination of extraction. The extraction of penicillin G was successfully performed by the ELM process with sodium carbonate in the internal phase.     

Sicherer und wirtschaftlicher Betrieb von Kraftwerken – Ergebnis der Forschung im Bereich Werkstoffe,Auslegung und Instandhaltung

Safe and Economic Operation of Power Plants – Research Results in the Field of Materials, Design and Maintenance Components of power plants which undergo high temperatures are subjected to complex loading situations. The requirements on the used materials result from the special operation conditions of the plants and have to be adjusted to the steadily growing requirements on higher efficiency of the complete power plant as well as to those of safe and economic operation. The expenses for control and downtimes are directly connected with economic efficiency and availability. However, in case of new procedures or components it is not possible to revert to the existing know‐how. Different failure mechanisms than known before can occur. The same goes for the load situation. Therefore the knowledge base has to be extended to in‐advance or even parallely running scientific examinations that life assessment and maintenance strategies can be applied which guarantee the operational reliability and the efficiency of the plant. The main emphasis of these F&E works has to be put on condition monitoring based on actual operational data, the standard materials’ and component’s behaviour (deformation, damage and failure behaviour) in connection with design of components and the related material laws. In the framework of applied AVIF projects, following problems are handled:. – qualification of materials by determinating parameters related to practise. – optimal design of components by making available material laws and numerical tools. – economic manufacturing of components by qualifying processing methods such as welding. – The results can be transferred to concepts for safe and economic operation of power plants, especially for newly introduced materials for which there is no operational experience available.     

All updateable objects in working memory are updated whenever any of them are modified: Evidence from the memory updating paradigm.

In a series of experiments, participants were required to keep track of 1 or 2 working memory (WM) objects, having to update their values in 80% of the trials. Updating cost, defined as the difference between update and non-update trials, was larger when 2 objects were involved compared with when there was only 1 object was involved. This finding was interpreted as evidence that the updating process encompasses both objects in WM, even though only 1 of them is actually updated. This feature of WM updating is limited to objects defined as "updateable," throughout the trial sequence. The results are explained by the need to reprogram the phonological loop when updating or the need for desynchronization followed by resynchronization of WM contents. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

回顾与展望──庆祝建院40周年

介绍了我院资源开发工程系的历史、现状和前景，指出了面临的问题及摆脱困境的途径。     

关于加强国土资源管理的思考

全文围绕树立和落实科学发展观这一主题 ,研究和探索如何在新时期、新阶段进一步做好国土资源管理工作的新思路、新途径和新方法。提出要进一步加强国土资源宏观管理 ,更好地为甘肃省经济社会的协调、可持续发展提供保障服务。     

人类聚居环境学对于居住区规划设计的启示

以人类聚居环境学的研究方法从若干方面对目前的居住区规划设计进行了一定的探讨,分析规划设计及建设方面目前存在的主要问题,提出以人类聚居环境学为指导的居住区规划设计理念。     

Memory of Distributed Computer Systems: Distinctive Features of Their Architectural-Structural Organization and Use

Distinctive features of architectural-structural organization and use of memory networks are considered with the aim of choosing an optimal configuration in designing distributed computer systems.     

谈谈职业教育的大众性

对职业教育的大众性问题进行了论述、实证分析和理论、政策、改革等思考。     

Bruchanalyse an Hohlgläsern

Failure analysis of hollow glasses The failure analysis is very important to clarify damages of hollow glasses. Damages of glass bottle through over pressure are very often linked with damages to persons. This is the reason why the causal research is from particular importance. Different surface characteristics of glass fragments as well as the fracture pattern give hints to the direction of the crack, the stress just before breakage and the reason of stress. A reconstruction of the bottle is a further helpful instrument for cause studies. The difference of the various characteristics of the surface will be explained. Further on there will be discussed different reasons and mechanism of fracture.