基于扩展染色Petri网的工作流过程模型

尽管已有广泛领域应用,但工作流系统在处理业务流程不确定的和动态的参数规格表时存在局限性。为此,本文提出基于扩展染色petri网的CPWF-net以及定义变迁行为和原子过程作为CPWF-net工作流模式结构的支持。这些工作流模式是从微观上进行处理,并可应用于动态不稳定的与时间和数据相关的环境中。本文通过CPWF-net执行程序检测工作流错误或异常执行状态,评估动态业务流程的整体执行时间,证实所提方法的有效性。     

Directions for improving manual fire suppression using a physically based computer simulation

The Swedish Fire Research Board and the U.S. Federal Emergency Management Agency are sponsoring a project to further the understanding of the basic mechanisms involved, as well as to support the development of standards for and to seek ways of improving the performance of portable fire suppression systems used by fire departments.This paper describes a physically based computer model developed to simulate one aspect of the problem: the manual suppression of postflashover fires. This includes: (1) an overview of the physical basis behind the model; (2) a comparison of model predictions with available experimental data, and (3) an analysis of fire suppression effectiveness using the model.The analysis concludes that, when direct access and extinguishment of the burning fuel is not possible, improved fire control occurs with water sprays having a Rosin-Rammler distribution of droplet sizes with volume-median-drop diameters in the 0.15 to 0.35 mm range. This agrees with available experimental data. It is also shown that fire fighting venting and standoff distance requirements may lead to more severe fires requiring more water for control; although venting and water spray induced air/gas flow also serve to channel hot steam and gases away from the fire fighter adding to his safety. The analysis also shows that allowing higher gas and surface temperatures at fire control through improved fire fighter protective clothing and equipment design reduces water flow rate requirements. Additional experimental work is recommended before all these conclusions are considered definitive. Reference: L. M. Pietrzak and G. A. Johanson, Directions for Improving Manual Fire Suppression Using a Physically Based Computer Simulation,Fire Technology, Vol. 22, No. 3, August, 1986, p. 184.     

空心铝型材挤压过程计算机仿真系统

试开发了一套基于计算机辅助设计和数值模拟的空心铝型材挤压过程计算机仿真系统,它涵盖了模具工艺设计的全过程,可以集成原有的和新建立的工艺设计知识。该系统包括空心型材挤压模具及坯料的参数化几何造型模块,并能分析分流桥的截面形状、分流孔的布置、焊合室的高度、工作带长度和阻流或者助流结构对金属流速分布的影响,模具的弹性变形对工作带有效长度和模孔尺寸的影响。     

Edge diffraction correction for 3D scattering center modeling based on the shooting and bouncing ray technique

In the traditional scattering center extraction method based on the shooting and bouncing ray(SBR) technique,only the physical optics contribution of the target is considered.However,the physical optics method is unable to describe the contribution of the actual edge diffraction.By comprehensively considering the specular reflection and edge diffraction contribution of the target,an edge diffraction correction method for 3D scattering center modeling based on the SBR technique is proposed.Using the SBR technique and combining the image domain ray tube integration and equivalent edge currents method,the edge diffraction correcting formula for the 3D inverse synthetic aperture radar image is derived.Simulation results show that the proposed method is able to effectively improve the modeling accuracy of the 3D scattering center.     

NDN数据提供者移动支持策略能耗建模与分析

基于数据提供者的移动节点在网络中的不同位置及不同移动速度,结合命名数据网络（NDN）请求者驱动的数据传输模式,提出了3类NDN移动支持策略的网络能耗解析表达式,为NDN移动网络的研究提供了形式化的建模方法.对这3类移动支持策略在不同场景下能耗的分析与比较结果表明,数据流行度分布、移动节点所处位置及移动速度对策略的能耗影响不尽相同,为后续探求最优能效的移动支持策略提供了理论参考.     

Simulation of polycrystalline aluminum tensile test with crystal plasticity finite element method

The crystal plasticity was implemented in the finite element method（FEM） software ABAQUS through the user subroutine UMAT. By means of discretizing the space at the grain level with the Voronoi diagram method, a polycrystal model was built and used in the FEM analysis. The initial orientation of each grain was generated based on the orientation distribution function（ODF）. The developed model was successfully applied in simulation of polycrystalline aluminium samples deformed by the tensile tests. The theoretical strain--stress relation was in good agreement with the experimental result. The simulation results show that the grain size has significant effect on the deformation behavior. The initial plastic deformation usually occurs at grain boundaries, and multiple slip often results in an enhanced local hardening at grain boundaries.     

Evidence for a Negative Correlation between Human Reactive Enamine-Imine Intermediate Deaminase A (RIDA) Activity and Cell Proliferation Rate: Role of Lysine Succinylation of RIDA

Reactive intermediate deaminase (Rid) proteins are enzymes conserved in all domains of life. UK114, a mammalian member of RidA subfamily, has been firstly identified as a component of liver perchloric acid-soluble proteins (L-PSP). Although still poorly defined, several functions have been attributed to the mammalian protein UK114/RIDA, including the reactive intermediate deamination activity. The expression of UK114/RIDA has been observed in some tumors, arousing interest in this protein as an evaluable tumor marker. However, other studies reported a negative correlation between UK114/RIDA expression, tumor differentiation degree and cell proliferation. This work addressed the question of UK114/RIDA expression in human non-tumor HEK293 cell lines and in some human tumor cell lines. Here we reported that human RIDA (hRIDA) was expressed in all the analyzed cell line and subjected to lysine (K-)succinylation. In HEK293, hRIDA K-succinylation was negatively correlated to the cell proliferation rate and was under the control of SIRT5. Moreover, K-succinylation clearly altered hRIDA quantification by immunoblotting, explaining, at least in part, some discrepancies about RIDA expression reported in previous studies. We found that hRIDA was able to deaminate reactive enamine-imine intermediates and that K-succinylation drastically reduced deaminase activity. As predicted by in silico analysis, the observed reduction of deaminase activity has been related to the drastic alterations of hRIDA structure inferred by K-succinylation. The role of hRIDA and the importance of its K-succinylation in cell metabolism, especially in cancer biology, have been discussed.     

Structural Investigation and Molecular Modeling Studies of Strobilurin-Based Fungicides Active against the Rice Blast Pathogen Pyricularia oryzae

The increasing emergence of fungicide-resistant pathogens requires urgent solutions for crop disease management. Here, we describe a structural investigation of new fungicides obtained by combining strobilurin and succinate dehydrogenase inhibitor pharmacophores. We identified compounds endowed with very good activity against wild-type Pyricularia oryzae, combined in some cases with promising activity against strobilurin-resistant strains. The first three-dimensional model of P. oryzae cytochrome bc1 complex containing azoxystrobin as a ligand was developed. The model was validated with a set of commercially available strobilurins, and it well explains both the resistance mechanism to strobilurins mediated by the mutation G143A and the activity of metyltetraprole against strobilurin-resistant strains. The obtained results shed light on the key recognition determinants of strobilurin-like derivatives in the cytochrome bc1 active site and will guide the further rational design of new fungicides able to overcome resistance caused by G143A mutation in the rice blast pathogen.     

面向对象的液压与气压回路工作原理仿真软件开发

详细介绍了用于液压与气压传动课程教学的“面向对象的液压与气压回路工作原理仿真软件”的开发，该软件采用VB6．0、AutoCAD及Microsoft Visio在Win2000操作系统上开发而成，采用了面向对象的建模技术，实现了液压与气压原理图的自动识别及工作原理仿真。     

An experimental evaluation of the effects of ripple current generated by the power conditioning stage on a proton exchange membrane fuel cell stack

In this article, an impedance model of the proton exchange membrane fuel cell stack (PEMFCS) is proposed. The proposed study employs an equivalent circuit of the PEMFCS derived by the frequency response analysis technique. An equivalent circuit for the PEMFCS is developed to evaluate the effects of ripple currents generated by the power-conditioning unit. The calculated results are then verified by means of experiments using a commercially available PEMFCS. The relationship between ripple current and fuel cell performance, such as power loss and fuel consumption, is investigated. Experimental results show that the ripple current can contribute up to a 6% reduction in the available output power. This paper was presented at the Fuel Cells: Materials, Processing, and Manufacturing Technologies Symposium sponsored by the Energy/Utilities Industrial Sector & Ground Transportation Industrial Sector and the Specialty Materials Critical Technologies Sector at the ASM International Materials Solutions Conference, October 13–15, 2003, in Pittsburgh, PA. The symposium was organized by P. Singh, Pacific Northwest National Laboratory, S.C. Deevi, Philip Morris USA, T. Armstrong, Oak Ridge National Laboratory, and T. Dubois, U.S. Army CECOM.