Glycerolipids as selective thrombin inhibitors from the fungus Stereum hirsutum

A dry extract of Stereum hirsutum exhibited a significant inhibitory activity on thrombin (34%). A bioassay oriented fractionation of the extract of Stereum hirsutum has led to the isolation of two active fractions. On the basis of spectroscopic data, chemical reactions, and GC-MS analysis, complex mixtures of diacylglycerophospholipids (DAGPs) and diacylglycerols (DGs) have been isolated and identified. Docking studies suggest that some isolated compounds could bind to the thrombin active site in a similar manner as previously reported phosphonate thrombin inhibitors.     

Criterion validity of the Holden Psychological Screening Inventory Social Symptomatology Scale in a prison sample.

The 36-item, self-report Holden Psychological Screening Inventory (HPSI; R. R. Holden, 1996) and the Psychopathy Checklist–Revised (PCL–R; R. D. Hare, 1991) were administered to 214 male, adult prison inmates in Canadian federal correctional facilities. The 12-item HPSI Social Symptomatology scale, a measure of antisocial behavior, demonstrated a large effect size in significantly differentiating between PCL–R-identified psychopaths and nonpsychopaths. HPSI scales not theoretically related to psychopathic behavior showed no such significant effects. Findings are interpreted as supporting the criterion validity of the Social Symptomatology scale and suggest that this brief, self-report screen has research and clinical merit. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Multiplex PCR system to track authorized and unauthorized genetically modified soybean events in food and feed

A diverse range of genetic elements has been used to develop genetically modified organisms (GMOs) over the last 18 years. Screening methods that target few elements, such as the Cauliflower Mosaic Virus 35S promoter (P-35S) and Agrobacterium tumefaciens nopaline terminator (T-nos), are not sufficient to screen GMOs. In the present study, a multiplex PCR system for all globally commercialized GM soybean events was developed to easily trace the events. For this purpose, screening elements of 24 GM soybean events were investigated and 9 screening targets were selected and divided into three individual triplex PCR systems: P-35S, ribulose-1,5-bisphosphate carboxylase small subunit promoter of Arabidopsis thaliana, T-nos, T-35S, pea E9 terminator, open reading frame 23 terminator of A. tumefaciens, proteinase inhibitor II terminator of potato, acetohydroxy acid synthase large subunit terminator of A. thaliana, and the revealed 3′ flanking sequences of DP-305423-1. The specificity of the assays was confirmed using thirteen GM soybean events as the respective positive/negative controls. The limit of detection of each multiplex set, as determined using certified reference materials of specific GM events, ranged from 0.03 to 0.5%, depending upon target. Furthermore, 26 food samples that contained soybean ingredients, which were purchased from the USA, China, Japan, and Korea, were analyzed, 17 of which contained one or more GM soybean events. These results suggest that the developed screening method can be used to efficiently track and identify 24 GM soybean events in food and feed.     

凹山选矿厂工艺流程的优化技术改造

凹山选矿厂通过进行中碎前安装圆振筛、一次磁选后加筛分作业、二次精选精矿用细筛把关、中矿再磨再选三项优化技术改造措施，使生产工艺流程基本适应原矿性质的变化，达到了生产能力、精矿品位、回收率三提高。     

Bayesian analysis of computer code outputs: A tutorial

The Bayesian approach to quantifying, analysing and reducing uncertainty in the application of complex process models is attracting increasing attention amongst users of such models. The range and power of the Bayesian methods is growing and there is already a sizeable literature on these methods. However, most of it is in specialist statistical journals. The purpose of this tutorial is to introduce the more general reader to the Bayesian approach.     

Reliability indicators

This is a review paper. It describes the state-of-the-art of the research on reliability indicators for either electronic or mechanical components. Typical component failure patterns are presented and discussed. The concept of component screening using reliability indicators is then outlined. The paper sketches a theoretical approach to the problem of detecting flaws in components. The approach is based on an old concept of energy imbalance in flawed objects.     

克拉玛依油田八区注入含少量硫化氢地层水的杀菌防腐蚀试验

本文报导新疆克拉玛依油田八区使用含少量H_2S地层水作为注入水的杀菌防腐蚀处理技术。从杀菌剂的室内筛选到现场投加试验均作了介绍。在现场投加杀菌剂试验中含H_2S水的腐蚀率由0.45mm/α降到0.10mm/α,达到了部颁标准。含H_2S水的腐蚀问题从而得到解决。     

深圳市胸透普查肺结核阳性检出率合理性评价

本文根据国际ＢＳＳ建议的原则估算了深圳市胸透普查肺结核阳性检出率的正当化水平,其中对于寿命损失或延长的社会经济学价值采用了人力资本法,结果为阳性检出率应不小于４３．３／万,若只考虑辐射致癌可能造成的死亡率增加和杜绝肺结核传染源后可能的死亡率降低,则阳性检出率应不小于３．３２／万,深圳市１９９６年肺结核发病率为５．２５／万左右,显然已不宜采用胸透普查法。     

安塞和子长原油破乳剂筛选研究--陕北原油破乳剂的筛选研究(Ⅱ)

本文对陕北安塞和子长原油用现有的不同破乳剂进行破乳脱水试验，筛选出对这些原油破乳脱水性能较好的破乳剂。     

Risk analysis using automatically synthesized robust accident scenarios and consequence assessment for chemical processes: Process partition and consequence analysis approach

Consequence analysis and risk assessment are very important in chemical process industries because of the potential risk of hazardous materials. In this paper, we introduce a new system for consequence analysis and risk management (CARM) and propose a new strategy for producing robust accident scenarios in quantitative risk assessment. The suggested synthesis method analyzes process elements and selects and generates robust accident scenarios that simulate the most possible worst-case accident that should be foremost considered. The scenario-reasoning scheme consists of three types of knowledge base (equipment property, material property, and process unit knowledge) and four reasoning algorithms (macro decomposition, equipment screening, equipment behavior analysis, and accident scenarios reasoning). The synthesized result of the analysis enhances the reliability of the generated accident scenario and prevents the risks from being overestimated. The obtained result, as easily confirmed by using CARM, should be more helpful in proper process design and emergency planning.