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941.
Aida Mehrpazhouh Seyed Naser Moghadas Tafreshi Mehdi Mirzababaei 《岩石力学与岩土工程学报(英文版)》2019,11(4):804-814
Pavements constructed over loosely compacted subgrades may not possess adequate California bearing ratio(CBR)to meet the requirements of pavement design codes,which may lead to a thicker pavement design for addressing the required strength.Geosynthetics have been proven to be effective for mitigating the adverse mechanical behaviors of weak soils as integrated constituents of base and sub-base layers in road construction.This study investigated the behaviors of unreinforced and reinforced sand with nonwoven geotextile using repeated CBR loading test(followed by unloading and reloading).The depth and number of geotextile reinforcement layers,as well as the compaction ratio of the soil above and below the reinforcement layer(s)and the compaction ratio of the sand bed,were set as variables in this context.Geotextile layers were placed at upper thickness ratios of 0.3,0.6 and 0.9 and the lower thickness ratio of 0.3.The compaction ratios of the upper layer and the sand bed varied between 85% and 97% to simulate a dense layer on a medium dense sand bed for all unreinforced and reinforced testing scenarios.Repeated CBR loading tests were conducted to the target loads of 100 kgf,150 kgf,200 kgf and 400 kgf,respectively(1 kgf = 9.8 N).The results indicated that placing one layer of reinforcement with an upper thickness ratio of 0.3 and compacting the soil above the reinforcement to compaction ratio of 97%significantly reduced the penetration of the CBR piston for all target repeated load levels.However,using two layers of reinforcement sandwiched between two dense soil layers with a compaction ratio of 97%with upper and lower thickness ratios of 0.3 resulted in the lowest penetration. 相似文献
942.
Junqi Chen Ying Tang Huaicheng Xiang Liang Fang Harshit Porwal Chunchun Li 《Journal of the European Ceramic Society》2018,38(14):4670-4676
Two Ag-containing microwave dielectric ceramics AgCa2B2V3O12 (B?=?Mg, Zn) with garnet structure were prepared through solid-state reaction method. Dense ceramics were obtained at low sintering temperatures, 665?°C for AgCa2Zn2V3O12 and 730?°C for AgCa2Mg2V3O12. Their microwave dielectric properties were characterized for the first time and analyzed by means of packing fraction, bond valence, octahedral distortion, Raman spectra and infrared reflectivity spectra. Both compounds displayed high chemical compatibility with Ag electrodes. Additionally, thermally stable ceramics with near-zero temperature coefficients of resonance frequency (τf) were achieved by forming ceramic composites with CaTiO3. 相似文献
943.
944.
Lovro Gorjan Riccardo Tonello Tutu Sebastian Paolo Colombo Frank Clemens 《Journal of the European Ceramic Society》2019,39(7):2463-2471
Thermoplastic filaments for Fused Deposition Modeling fabrication of mullite ceramic components were produced from a polymethylsiloxane ceramic precursor, γ-Al2O3 powder and ethylene vinyl acetate (EVA) as an organic, elastomeric binder. Two micron-sized γ-Al2O3 powders with different particle size distributions were used. Both type of powders could be successfully 3D printed, however γ-Al2O3 with finer particle size resulted in better quality of printed parts with much smoother surface.Sintering experiments showed that mullite starts forming already at 1250 °C, but a final sintering of 1550 °C is necessary to achieve pure mullite using the coarse powder, while some residual α-Al2O3 was present when using finer powder.Results demostrate that Fused Deposition Modeling can be used to shape preceramic polymers to generate large scale components with a complex shape in which, during firing, the siloxane produces highly reactive silica that allows for the in-situ formation of silicate ceramic phases, such as mullite. 相似文献
945.
Selection and breeding can be used to fight transmission of infectious diseases in livestock. The prevalence in a population depends on the susceptibility and infectivity of the animals. Knowledge on the genetic background of those traits would facilitate efficient selection for lower disease prevalence. We investigated the genetic background of host susceptibility and infectivity for digital dermatitis (DD), an endemic infectious claw disease in dairy cattle, with a genome-wide association study (GWAS), using either a simple linear mixed model or a generalized linear mixed model based on epidemiological theory. In total, 1,513 Holstein-Friesian cows of 12 Dutch dairy farms were scored for DD infection status and class (M0 to M4.1) every 2 wk for 11 times; 1,401 of these cows were genotyped with a 75k SNP chip. We performed a GWAS with a linear mixed model on 10 host disease status traits, and with a generalized linear mixed model with a complementary log-log link function (GLMM) on the probability that a cow would get infected between 2 scorings. With the GLMM, we fitted SNP effects for host susceptibility and host infectivity, while taking the variation in exposure of the susceptible cow to infectious herd mates into account. With the linear model we detected 4 suggestive SNP (false discovery rate < 0.20), 2 for the fraction of observations a cow had an active lesion on chromosomes 1 and 14, one for the fraction of observations a cow had an M2 lesion on at least one claw on chromosome 1 (the same SNP as for the fraction of observations with an active lesion), and one for the fraction of observations a cow had an M4.1 lesion on at least one claw on chromosome 10. Heritability estimates ranged from 0.09 to 0.37. With the GLMM we did not detect significant nor suggestive SNP. The SNP effects on disease status analyzed with the linear model had a correlation coefficient of only 0.70 with SNP effects on susceptibility of the GLMM, indicating that both models capture partly different effects. Because the GLMM better accounts for the epidemiological mechanisms determining individual disease status and for the distribution of the y-variable, results of the GLMM may be more reliable, despite the absence of suggestive associations. We expect that with an extended GLMM that better accounts for the full genetic variation in infectivity via the environment, the accuracy of SNP effects may increase. 相似文献
946.
A numerical model based on Finite Element Method (FEM) - Discrete Element Method (DEM) coupling is used to reproduce well controlled laboratory experiments that simulate circular cavity openings under granular embankments reinforced by a geotextile. The numerical deflection of the geotextile, the surface settlement and the soil expansion factor were investigated for various embankment heights, diameter ratios, cavity-opening modes, soil properties, and geotextile stiffnesses, and then compared to the results of laboratory tests. The load transfer mechanisms were also investigated. Good agreement between numerical and experimental results is shown, thus demonstrating the relevance of the numerical model. Complementary to the experiments, a numerical sensitivity analysis, that allows highlighting the influence of the main parameters and improving experimental observation, was also performed. 相似文献
947.
Matthew Jordan Dellinger Maureen Lyons Robin Clark Jared Olson Noel Pingatore Michael Ripley 《Journal of Great Lakes research》2019,45(5):969-975
The presence of persistent bioaccumulative toxics (PBT) in aquatic food chains complicates decision processes of people with a strong culture of fish consumption. This environmental contamination is especially problematic for Native American populations in the Laurentian Great Lakes region (Anishinaabeg). Pursuing the growing discipline of environmental health literacy (EHL) may help reduce toxic exposures, support healthy decision-making, and combat health deficits. Our goals for this research were first to improve environmental health literacy using novel technologies and second to help define environmental health literacy metrics that can be tracked over time, especially regarding culturally-contextualized health interests. We recently reported that a mobile app (Gigiigoo'inaan App) presenting personalized, culturally-contextualized fish consumption advice may improve EHL for the Anishinaabeg. Gigiigoo'inaan App safely supports desired fish consumption rates by putting local data into the hands of the Anishinaabeg. We conducted a pre-test post-test evaluation with 103 Aninishinaabe adults. Participants estimated their current fish meal consumption over a hypothetical month before exposure to the software and then planned their future consumption of fish meals in a month after using the mobile app. Significantly more monthly traditional fish meals on average (Median: 4 vs 2, p = 0.0005) were selected when using the app versus pre-exposure to the app. Significantly more traditional grams of fish were also selected during use of the app relative to the pretest (Median: 680.39 g vs 453.59 g, p = 0.0007). These increases were accompanied by widespread (97%) adherence to conventional advice that minimizes PBT exposure health effects (ATSDR minimum risk levels). 相似文献
948.
José Luiz Ernandes Dias Filho Paulo Cesar de Almeida Maia Gustavo de Castro Xavier 《Geotextiles and Geomembranes》2019,47(6):792-797
This study reports results for creep deformation with data acquired in 72 h of testing. A system capable of performing 8 simultaneous tests was used to test four woven geotextiles of different weights, following all of the recommendations outlined in the standards related to equipment setup. A mathematical model was used to generate time-dependent creep curves for four different load levels up to 40% for each sample and using a database which presented stage II creep conditions (i.e. without rupture) through the end of the tests, up to 10,000 h. The coefficients of variation for the conventional creep tests were below 10%. The compatibility between the experimental data and the model indicates that short-term (72 h) loading tests may be used to extrapolate long-term creep deformation in woven geotextiles. 相似文献
949.
Dynamic interactions between lipid metabolism, gut permeability, and systemic inflammation remain unclear in the context of obesity. Milk polar lipids, lipids derived from the milk fat globule membrane, could positively affect the aforementioned obesity-related endpoints. This study aimed to test the hypotheses that milk polar lipids will reduce gut permeability, systemic inflammation, and liver lipid levels, and differentially affect the hepatic expression of genes associated with fatty acid synthesis and cholesterol regulation in preexisting obesity. We fed 3 groups of C57BL/6J ob/ob mice (n = 6 per group) for 2 wk: (1) a modified AIN-93G diet (CO) with 34% fat by energy; (2) CO with milk gangliosides (GG) at 0.2 g/kg of diet; and (3) CO with milk phospholipids (PL) at 10 g/kg of diet. The GG and PL were provided as semi-purified concentrates and replaced 2.0% and 7.2% of dietary fat by energy. The GG and PL did not affect total food intake, weight gain, fasting glucose, or gut permeability. The PL decreased liver mass and the mesenteric fat depot compared with the CO. The GG increased tight junction protein occludin in colon mucosa compared with the CO. The GG and PL decreased tight junction protein zonula occludens-1 in jejunum mucosa compared with the CO. Plasma endotoxin increased during the study but was unaffected by the treatments. Compared with the CO and GG, the PL increased plasma sphingomyelin and plasma IL-6. The GG and PL differentially regulated genes associated with lipid metabolism in the liver compared with the CO. Regarding general effects on lipid metabolism, the GG and PL decreased lipid levels in the liver and the mesenteric depot, and increased lipid levels in the plasma. Diet consumption decreased significantly when the ob/ob mice were kept in metabolic cages, which were not big enough and resulted in unwanted animal deaths. Future studies may keep this in mind and use better metabolic equipment for ob/ob mice. In conclusion, dietary milk polar lipids may have limited beneficial effects on gut barrier integrity, systemic inflammation, and lipid metabolism in the context of severe obesity. 相似文献
950.
Luiz G. Siqueira Eduardo K. Arashiro Alberto M. Ghetti Eliza D. Souza Luiz F. Feres Luiz F. Pfeifer Jeferson F. Fonseca João H. Viana 《Journal of dairy science》2019,102(6):5612-5622
Our objective was to retrospectively compare pregnant versus nonpregnant cattle in terms of vascular and morphometric changes in corpora lutea between d 12 and 20 following timed artificial insemination (TAI). Crossbred (Gir × Holstein) lactating dairy cows (n = 136) and heifers (n = 111) were bred after synchronizing ovulations using an estradiol plus progesterone (P4)-based protocol. Corpus luteum (CL) characteristics (area, echotexture, blood flow) were recorded at 48-h intervals from d 12 to 20 following TAI using an ultrasound equipped with color Doppler. Blood samples were collected to determine CL function (plasma P4). Pregnancy diagnosis was performed at d 30. Quantitative assessment of colored pixels within the CL was performed using ImageJ software (National Institutes of Health, Bethesda, MD) and echotexture was quantified using custom software. Continuous variables such as luteal tissue area (LTA), CL blood flow (CLBF), adjusted CLBF (ratio LTA:CLBF), mean pixel value (MPV), pixel heterogeneity (HETER), and plasma P4 were analyzed retrospectively as repeated measures (d 12 to 20) in pregnant versus nonpregnant females using PROC MIXED (SAS Institute Inc., Cary, NC). Main effects were pregnancy status, day of cycle, and their interaction. Further analyses used only data from d 16, because this was the earliest time point of deviation between CLBF of pregnant and nonpregnant animals. We created quartiles for each variable and calculated the risk of pregnancy within quartile. Differences were determined using the chi-squared test. Plasma P4 was significantly higher in prospective pregnant versus nonpregnant cattle on d 18 and 20, whereas LTA differed only on d 20. On d 16, CLBF and adjusted CLBF diverged between pregnant and nonpregnant, followed by a progressive reduction in the latter until d 20. Mean pixel value was not affected by pregnancy status, but HETER was lower on d 20 in pregnant than in nonpregnant cattle. Likelihood of pregnancy increased from quartile (Q)1 (lowest values) to Q4 (highest) of CLBF (Q4 vs. Q1, odds ratio = 32.8, 95% confidence interval: 9.6 to 112.1) and adjusted CLBF [Q4 vs. Q1, odds ratio = 25.4, 95% confidence interval: 8.1 to 80.4), whereas a lower risk of pregnancy was observed only for animals within Q1 of plasma P4 [Q4 vs. Q1, odds ratio = 3.1, 95% confidence interval: 1.3 to 7.2). Day 16 quartiles of LTA, MPV, and HETER did not affect odds of pregnancy. In conclusion, we identified distinct CLBF patterns as early as 16 d after TAI and confirmed that CL function is lost by a reduction in blood flow, which precedes physical regression. 相似文献