Passive Picoinjection Enables Controlled Crystallization in a Droplet Microfluidic Device

Segmented flow microfluidic devices offer an attractive means of studying crystallization processes. However, while they are widely employed for protein crystallization, there are few examples of their use for sparingly soluble compounds due to problems with rapid device fouling and irreproducibility over longer run‐times. This article presents a microfluidic device which overcomes these issues, as this is constructed around a novel design of “picoinjector” that facilitates direct injection into flowing droplets. Exploiting a Venturi junction to reduce the pressure within the droplet, it is shown that passive injection of solution from a side‐capillary can be achieved in the absence of an applied electric field. The operation of this device is demonstrated for calcium carbonate, where highly reproducible results are obtained over long run‐times at high supersaturations. This compares with conventional devices that use a Y‐junction to achieve solution loading, where in‐channel precipitation of calcium carbonate occurs even at low supersaturations. This work not only opens the door to the use of microfluidics to study the crystallization of low solubility compounds, but the simple design of a passive picoinjector will find wide utility in areas including multistep reactions and investigation of reaction dynamics.     

Compact,ultra-low vibration,closed-cycle helium recycler for uninterrupted operation of MEG with SQUID magnetometers

A closed-cycle helium recycler was developed for continuous uninterrupted operation for magnetometer-based whole-head magnetoencephalography (MEG) systems. The recycler consists of a two stage 4 K pulse-tube cryocooler and is mounted on the roof of a magnetically shielded room (MSR). A flexible liquid helium (LHe) return line on the recycler is inserted into the fill port of the MEG system in the MSR through a slotted opening in the ceiling. The helium vapor is captured through a line that returns the gas to the top of the recycler assembly. A high-purity helium gas cylinder connected to the recycler assembly supplies the gas, which, after it is liquefied, increases the level of LHe in the MEG system during the start-up phase. No storage tank for evaporated helium gas nor a helium gas purifier is used. The recycler is capable of liquefying helium with a rate of ∼17 L/d after precooling the MEG system. It has provided a fully maintenance-free operation under computer control for 7 months without refill of helium. Although the recycler is used for single-orientation operation at this initial testing site, it is designed to operate at ±20° orientations, allowing the MEG system to be tilted for supine and reclining positions. Vibration of the recycler is dampened to an ultra-low level by using several vibration isolation methods, which enables uninterrupted operation during MEG measurements. Recyclers similar to this system may be quite useful even for MEG systems with 100% magnetometers.     

活塞式液体流量标准装置体积校准方法的探讨

对活塞式液体流量标准装置体积校准方法进行了研究,基于理想圆柱体模型建立了活塞装置体积模型,引入修正系数对所建立的体积模型进行修正,并利用质量守恒定律提出采用质量法对活塞装置进行体积校准.对修正系数进行赋值分析和不确定度评定,结果表明5L及以上体积的扩展不确定度优于0.05％.该方法操作简便,可控性好,结果准确可靠.     

一种信息泄漏的新方式及其应对策略

文章基于验证和解决信息设备内存储器存在的信息安全泄漏隐患,提出了内存储器信息泄漏概念并对内存储器存在信息泄漏的原因做了介绍。实测发现现有内存储器存在信息泄漏状况,基于此,该文提出了基于公共信息网和文件型恶意代码窃取的内存储器信息泄漏方式并完成了实测过程,文章结论对于信息安全保密领域的内存储器信息泄漏隐患防护具有重要意义,尤其适用于安全隔离和信息交换等信息系统领域,具有较广泛的应用前景和重大的社会意义。     

煤矿电气安全关键技术研究

分析了2005—2009年全国重特大瓦斯爆炸事故的火源,得出了由电气火源引爆瓦斯事故最多且达48.1%的结论,并分析了矿用电气设备的安全性能,提出了矿用电气设备的使用场所及安全要求:(1)煤矿监控、通信、控制、信号等弱电系统和设备应优选本质安全型电气设备,设备之间传输的信号必须是本质安全型信号;(2)大功率电气设备应优选隔爆型电气设备,隔爆型电气设备宜将接线腔与主腔分腔布置;(3)当瓦斯浓度达到爆炸浓度时严禁开关特殊型矿灯;(4)低瓦斯矿井井底车场等非爆炸性环境宜选用矿用防爆型电气设备;(5)煤与瓦斯突出矿井严禁使用架线电机车和矿用一般型电气设备;(6)井下电气设备的欠压保护和失压保护应有延时措施,减少局部通风机停电次数;(7)井下排水设备宜选用大功率潜水泵;(8)开关等电气设备应设置在全风压进风处,若不能满足,必须设置甲烷传感器,并具备甲烷超限断电闭锁功能。文章对提高煤矿电气安全性、避免或减少瓦斯爆炸和淹井等事故发生具有指导作用。     

矿用变频器功率器件选型及其驱动保护设计

分析了煤矿井下设备对变频器功率器件IGBT的需求和在IGBT选型时需要考虑的电气参数,介绍了基于2SD315模块的IGBT驱动保护电路的设计。实际应用表明,采用文中介绍的方法选用的IGBT和设计的驱动保护电路后,变频器运行稳定,IGBT驱动有效,保护完善。     

基于Internet的物联网系统中设备互联和实时在线技术

针对物联网系统中信息交互的实时性和系统自治特性,提出一种基于Internet和嵌入式设备构建物联网的技术;通过基于客户/服务器的体系结构和面向连接的设备实时在线技术实现信息交互的实时性,进一步通过一种服务器地址自动迁移技术实现基于Inter-net的嵌入式设备物联网的系统自治特性;通过多台嵌入式设备组网进行实际测试验证,系统满足良好的扩展性和设备即插即用特性,设备间数据通信相应时间低于1s,具有良好的实时性,可广泛应用于嵌入式设备的互联互通。     

双自由度后坐保险机构敏感因子对比

目前国内对双自由度后坐保险机构的研究大多集中于对其动态特性的分析和仿真,对机构运动影响敏感因子的分析很少。借助计算机仿真,运用正交试验设计方法对双自由度后坐保险机构敏感因子进行分析,确定各敏感因子对机构影响程度的主次顺序以及主要敏感因子。结果表明上质量块质量对其运动特性影响最大并为主要敏感因子,然后依次是惯性簧刚度,惯性簧长度和下质量块质量的影响。     

嵌入式VxWorks系统下的CPCI设备驱动程序开发

具体分析了VxWorks下PCI总线的配置空间结构和地址映射,并采用CPCI9054芯片,结合一个信号产生、数据采集处理系统的工程实例,详细阐述了VxWorks下CPCI设备驱动程序的开发实现方法和具体步骤,并给出了部分关键代码.应用结果表明,该方法可移植性较高,可操作性强,对于了解和开发CPCI驱动程序具有一定的参考...     

Critical point analysis using domain lifting for fast geometry queries

In this paper, a general scheme for solving coherent geometric queries on freeform geometry is presented and demonstrated on a variety of problems common in geometric modeling. The underlying strategy of the approach is to lift the domain of the problem into a higher-dimensional space to enable analysis on the continuum of all possible configurations of the geometry. This higher-dimensional space supports analysis of changes to solution topology by solving for critical points using a B-spline-based constraint solver. The critical points are then used to guide fast, local methods to robustly update repeated queries. This approach effectively combines the speed of local updates with the robustness of global search solutions. The effectiveness of the domain lifting scheme (DLS) is demonstrated on several geometric computations, including accurately generating offset curves and finding minimum distances. Our approach requires a preprocessing step that computes the critical points, but once the topology is analyzed, an arbitrary number of geometry queries can be solved using fast local methods. Experimental results show that the approach solves for several hundred minimum distance computations between planar curves in one second and results in a hundredfold speedup for trimming self-intersections in offset curves.