配制BB肥用辅料的生产技术

由于以高浓度粒状基础原料生产不同配比BB肥时,需要外加低浓度填充料,介绍生产低氮(或者低氮磷)粒状肥与低钾(或低钾磷)粒状肥(称辅料)的生产技术,并可加入所需微量元素,同时介绍了利用这种辅料配制BB肥(14912,151515)的配料比。     

Quantification of the in situ DRIFT spectra of Pt/K/γ-A12O3 NOx adsorber catalysts

A method to quantify DRIFT spectral features associated with the in situ adsorption of gases on a NO_x adsorber catalyst, Pt/K/Al₂O₃, is described. To implement this method, the multicomponent catalyst is analysed with DRIFT and chemisorption to determine that under operating conditions the surface comprised a Pt phase, a pure γ-Al₂O₃ phase with associated hydroxyl groups at the surface, and an alkalized-Al₂O₃ phase where the surface –OH groups are replaced by –OK groups. Both DRIFTS and chemisorption experiments show that 93–97% of the potassium exists in this form. The phases have a fractional surface area of 1.1% for the 1.7 nm-sized Pt, 34% for pure Al₂O₃ and 65% for the alkalized-Al₂O₃. NO₂ and CO₂ chemisorption at 250 °C is implemented to determine the saturation uptake value, which is observed with DRIFTS at 250 °C. Pt/Al₂O₃ adsorbs 0.087 μmol CO₂/m²and 2.0 μmol NO₂/m², and Pt/K/Al₂O₃ adsorbs 2.0 μmol CO₂/m²and 6.4 μmol NO₂/m². This method can be implemented to quantitatively monitor the formation of carboxylates and nitrates on Pt/K/Al₂O₃ during both lean and rich periods of the NO_x adsorber catalyst cycle.     

3K行星轮系传动的齿数选择方向

本文通过对3K行星轮系的传动比计算,将该机构的运动分解为两种相串联的ZK-H运动,其中一为简单的单排2K-H(负号)机构,另一为有双联行星轮的双排ZK-H(NN型)机构.3K机构传动比大,主要取决于此双排2K-H机构.文中对其进行了运动及受力分析,计算了最大圆周力及最大圆周速度,均证明了在两个内啮合大齿轮中,以固定的内啮合大齿轮齿数大于另一内啮合大齿轮的齿数为佳,从而为设计3K轮系传动提供了齿数选择的方向.     

Kynurenic Acid and Its Analog SZR104 Exhibit Strong Antiinflammatory Effects and Alter the Intracellular Distribution and Methylation Patterns of H3 Histones in Immunochallenged Microglia-Enriched Cultures of Newborn Rat Brains

Kynurenic acid (KYNA) is implicated in antiinflammatory processes in the brain through several cellular and molecular targets, among which microglia-related mechanisms are of paramount importance. In this study, we describe the effects of KYNA and one of its analogs, the brain-penetrable SZR104 (N-(2-(dimethylamino)ethyl)-3-(morpholinomethyl)-4-hydroxyquinoline-2-carboxamide), on the intracellular distribution and methylation patterns of histone H3 in immunochallenged microglia cultures. Microglia-enriched secondary cultures made from newborn rat forebrains were immunochallenged with lipopolysaccharide (LPS). The protein levels of selected inflammatory markers C–X–C motif chemokine ligand 10 (CXCL10) and C–C motif chemokine receptor 1 (CCR1), histone H3, and posttranslational modifications of histone H3 lys methylation sites (H3K9me3 and H3K36me2, marks typically associated with opposite effects on gene expression) were analyzed using quantitative fluorescent immunocytochemistry and western blots in control or LPS-treated cultures with or without KYNA or SZR104. KYNA and SZR104 reduced levels of the inflammatory marker proteins CXCL10 and CCR1 after LPS-treatment. Moreover, KYNA and SZR104 favorably affected histone methylation patterns as H3K9me3 and H3K36me2 immunoreactivities, and histone H3 protein levels returned toward control values after LPS treatment. The cytoplasmic translocation of H3K9me3 from the nucleus indicated inflammatory distress, a process that could be inhibited by KYNA and SZR104. Thus, KYNA signaling and metabolism, and especially brain-penetrable KYNA analogs such as SZR104, could be key targets in the pathway that connects chromatin structure and epigenetic mechanisms with functional consequences that affect neuroinflammation and perhaps neurodegeneration.     

Whole Body Ip6k1 Deletion Protects Mice from Age-Induced Weight Gain,Insulin Resistance and Metabolic Dysfunction

(1) Background: We previously demonstrated that disruption of IP6K1 improves metabolism, protecting mice from high-fat diet-induced obesity, insulin resistance, and non-alcoholic fatty liver disease and steatohepatitis. Age-induced metabolic dysfunction is a major risk factor for metabolic diseases. The involvement of IP6K1 in this process is unknown. (2) Methods: Here, we compared body and fat mass, insulin sensitivity, energy expenditure and serum-, adipose tissue- and liver-metabolic parameters of chow-fed, aged, wild type (aWT) and whole body Ip6k1 knockout (aKO) mice. (3) Results: IP6K1 was upregulated in the adipose tissue and liver of aWT mice compared to young WT mice. Moreover, Ip6k1 deletion blocked age-induced increase in body- and fat-weight and insulin resistance in mice. aKO mice oxidized carbohydrates more efficiently. The knockouts displayed reduced levels of serum insulin, triglycerides, and non-esterified fatty acids. Ip6k1 deletion partly protected age-induced decline of the thermogenic uncoupling protein UCP1 in inguinal white adipose tissue. Targets inhibited by IP6K1 activity such as the insulin sensitivity- and energy expenditure-inducing protein kinases, protein kinase B (PKB/Akt) and AMP-activated protein kinase (AMPK), were activated in the adipose tissue and liver of aKO mice. (4) Conclusions: Ip6k1 deletion maintains healthy metabolism in aging and thus, targeting this kinase may delay the development of age-induced metabolic dysfunction.     

高温超导体处于4.2K温区的临界态模型

本文基于高温超导体在４．２Ｋ温区的电磁行为，通过观察高温超导体在４．２Ｋ温区的Ｊｃ－Ｂ曲线提出了一种不同于Ｂｅａｎ模型和Ｋｉｍ模型的新的临界态模型，这种模型能克服Ｂｅａｎ模型和Ｋｉｍ模型的不足之处。本文也用这种模型简要地计算了磁通在超导体内的穿透情况。     

Antiproliferative effect of aaptamine on human chronic myeloid leukemia k562 cells

We previously isolated aaptamine, a benzonaphthyridine alkaloid, from marine sponge Aaptos suberitoids. In this study, we investigated the anti-proliferative effect of aaptamine on chronic myeloid leukemia (CML) K562 cells. Aaptamine inhibited growth of K562 with a GI50 as 10 μM, and arrested cell cycle at G2/M phase. Western blot analysis indicated that aaptamine induced p21 expression in K562 cells. Moreover, p21 promoter was activated by aaptamine treatment in p21 transfected K562 cells. Since K562 is p53 negative, aaptamine was demonstrated to be a p53-independent p21 inducer in CML cells.     

K4体系KTP晶体的制备及其性能研究

本文选用K4P2O7助溶剂体系生长KTP晶体,所生长的晶体具有低吸收率和蓝、绿光波段抗灰迹性能,确定其最佳生长配比为KTP/K4 =0.8 mol/mol,测定其饱和点为850℃左右,从饱和点缓慢降温到820℃所生长晶体质量最佳,并对其进行了PCI抗灰迹吸收测试、倍频效率测试、电导率测试.结果表明:在同样原料纯度的情况下,吸收系数只有普通K6体系KTP晶体的十几分之一;1064 nm调Q到绿光的转化效率为61.8％(普通KTP转化效率为50％);在1 kV直流长时间加压条件下,Z向电导率达到10-10S/cm量级,较普通K6体系生长的KTP晶体低2～3个数量级.     

二苯胺磺酸钠指示剂终点颜色变化的探讨

以二苯胺磺酸钠作指示剂的重铬酸钾测定法是一种常用的容量分析法,主要用来测定样品中铁的含量,但在测定时,有时终点颜色得不到正常的紫色,而是出现墨黑色.文章对此现象进行了探讨并提出了一些解决方案.     

ZnO和CuO烧结助剂对KNN压电陶瓷性能的影响

以微波水热法制备的KNN粉体为原料,添加1mol%ZnO、1mol%CuO烧结助剂,采用传统电子陶瓷制备方法,研究了烧结助剂对KNN陶瓷的陶瓷体积密度、显微结构和电性能的影响,结果表明:添加烧结助剂ZnO和CuO可以降低KNN陶瓷的烧结温度,提高KNN陶瓷的体积密度;与此同时,ZnO和CuO添加后降低了KNN无铅压电陶瓷的压电常数d33、介电常数ε33T/ε0,但机械品质因数Qm得到很大的提高,介电损耗tanδ明显降低。其中CuO烧结助剂可以使KNN陶瓷的d33由142 pC/N降低至118 pC/N,Qm值由82提高至427,tanδ由2.46%降低至0.64%。