锻造工艺对TC4-DT和TC21损伤容限型钛合金疲劳裂纹扩展速率的影响

研究了不同锻造工艺（近β锻造、准β锻造、两相区锻造）对TC4-DT和TC21损伤容限型钛合金疲劳裂纹扩展速率的影响,对比分析了不同锻造工艺的微观组织和疲劳裂纹扩展路径的关系。研究结果表明,与两相区锻造和近β锻造相比,TC4-DT和TC21钛合金经准β锻造后的疲劳裂纹扩展速率最低。准β锻造的锻件疲劳裂纹扩展路径曲折程度大,断口表面粗糙度大,有效地降低了疲劳裂纹扩展速率。     

Effect of RBM10 on regulating the proliferation and metastasis activity of human hepatocellular carcinoma cells by affecting the stability of miR-21

In recent decades, RNA binding motif (RBM) proteins have been widespread concerned by researchers. Among them, RBM5 is considered as a potential tumor suppressor gene in HCC. RBM10, also belonging to the RBM family, have similar structure and high homology with RBM5, indicating its potential as potential tumor suppressor genes. However, the role of RBM10 in tumors is controversial. The purpose of this study was to analyze the expression correlation and functional relationship of miR-21 and RBM10 in human hepatocellular carcinoma (HCC) tissues and corresponding tumor cells. Bioinformatics analysis showed that miR-21 and RBM10 were both highly expressed in HCC; similarly, the expression levels of miR-21 and RBM10 in HCC cells were significantly higher than those in normal hepatocytes. There was a positive correlation between miR-21 and RBM10. Furthermore, knockdown of RBM10 inhibited the proliferation, migration and invasion of SNU-398 cells, and simultaneous overexpression of miR-21 attenuated this inhibitory effect. Meanwhile, overexpressing RBM10 could promote the proliferation, migration and invasion of Hep G2 cells; while the stability of miR-21 could be reduced by knocking down RBM10. On the whole, the findings of this study indicate that RBM10 is involved in regulating the function and activity of human HCC cells by affecting the stability of miR-21. RBM10 cannot be simply summarized as a tumor suppressor or oncogene. Further studies are needed to clarify the role of RBM10 in tumors.     

21世纪最具发展前景的近净成形技术——半固态加工

就半固态加工技术的制坯机制、半固态充填流变学、高压下结晶凝固和力学成形理论进行了讨论,在此基础上, 就目前流变成形和触变成形的工艺过程、特点以及应用前景作了分析,指出由于半固态加工与其他成形工艺相比具有许多 优势,是一种潜在的、正逐步为世人认识的最具发展前景的近净成形技术之一。     

基于MSP430的超声波热量表的设计

设计以超低功耗单片机MSP430F4371为主要控制器的小管道热量表。采用高精度时间测量芯片TDC-GP21实现温度测量并通过超声波实现管道液体流量测量;采用M-BUS和红外实现通信并数据加密,可实现现场手持仪抄表和远程抄表;采用汉显,方便居民查看。通过校表台试验,本产品功耗低、误差小于1%且稳定。     

基于HNC-21T的梯形槽加工宏程序开发

在轴类零件中,梯形槽的加工十分常见。由于HNC-21T数控车床上没有像FANUC系统的切槽循环指令,使得切槽加工编程繁琐、效率低下。针对这一情况,基于HNC-21T,通过宏程序开发出了G75切梯形槽循环指令。实践证明,对于这一类型的零件,该指令在简化编制程序、提高切削效率方面是可行的。     

新世纪的制造技术与机床

文章结合国际生产工程学会（CIRP）第50届年会的情况,指出21世纪的机械制造业的特色将是信息化、智能化、网络化、集成化和不断创新的绿色制造,而生物技术、纳米技术、微机电系统将成为机械制造业的重要发展方向。     

基于Mastercam的CK6142数控车床自动编程

文中介绍了Mastercam后置处理程序的功能、结构以及定制方法,并据此提出了生成HNC_21T华“中世纪星”数控系统的后置处理程序的策略,完美实现了CK6142数控车床在Mastercam系统中的自动编程,并为其它类型数控机床利用通用CAD/CAM软件自动编程提供了可供借鉴的思路。     

铝合金MIG+激光复合焊接工艺研究

研究轻量化轿车用3A21铝合金M IG 激光复合焊接工艺,探讨工艺参数对焊缝成型的影响规律及激光与电弧的复合作用。试验结果表明,采用M IG 激光复合焊接工艺可以显著提高熔深和焊速,达到采用小功率激光焊机实现铝合金的激光焊接。在比较宽的工艺参数范围内M IG YAG激光复合焊接铝合金具有焊缝成型美观等优点,熔深和焊速均显著提高,大大提高生产率。     

21世纪初中国建筑在多元化设计背景下的发展特点

21世纪,在各种新技术、新材料和各种各样的设计思潮的影响下,中国建筑兼容并蓄,慢慢凸显出了一些自己的发展特点。本文通过分析21世纪以来中国的典型建筑案例,对这一时期中国建筑的特点进行了总结和论述,并探析这些特点在中国建筑中的表现形式。