“Biaxiality Effect” on the Energy Dissipated by Elastoplastic Base-Isolators

A plane elastic-plastic solid body presenting kinematic hardening is used to simulate a pair of dampers at the base of a rigid structure and determine the energy dissipation under conditions of assigned, homogeneous cyclic loading. The well-known von Mises theory of plasticity is applied with the aim of obtaining analytical solutions to the problem. Such solutions are arrived at by first calculating the Odqvist parameter, which yields dimensionless relations that depend on the external loads and mechanical properties of the material. The results, in terms of dissipated energy, are given for the case of a sinusoidal process, represented with the help of dimensionless parameters useful for engineering applications.     

阿曼Daleel油田分支井钻井液技术研究

对Daleel油田作业5区三分支水平井DL-59井井下复杂情况分析,室内测定了引起复杂情况的Nahr Umr泥页岩地层的矿物组分和粘土矿物含量,优选了适应在该泥页岩地层215.9 mm造斜井段的钻井液配方中的各种处理剂,最后研制出钻井液配方,通过DL-73井应用后,取得了良好的防塌效果.     

On the Locus of Speed-Accuracy Trade-Off in Reaction Time: Inferences From the Lateralized Readiness Potential.

Lateralized readiness potentials (LRPs) were used to determine the stage(s) of reaction time (RT) responsible for speed-accuracy trade-offs (SATs). Speeded decisions based on several types of information were examined in 3 experiments, involving, respectively, a line discrimination task, lexical decisions, and an Erikson flanker task. Three levels of SAT were obtained in each experiment by adjusting response deadlines with an adaptive tracking algorithm. Speed stress affected the duration of RT stages both before and after the start of the LRP in all experiments. The latter effect cannot be explained by guessing strategies, by variations in response force, or as an indirect consequence of the pre-LRP effect. Contrary to most models, it suggests that SAT can occur at a late postdecisional stage. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Exact solution of elasto-plastic stresses in a metal-matrix composite beam of arbitrary orientation subjected to transverse loads

An analytical elasto-plastic stress analysis is presented for a metal-matrix composite beam of arbitrary orientation subjected to a single transverse force applied to the free end of the beam and a uniformly distributed load. The material is assumed to be perfectly plastic in the elasto-plastic solution. A composite consisting of stainless-steel-reinforced aluminum was produced for this work. Sample problems are given for various orientation angles. Elastic, elastoplastic and residual normal and shear stresses are calculated. The location of the elasto-plastic boundary of the beam is obtained according to the x coordinates of the beam.     

Scale Transition in Steel-Concrete Interaction. II:?Applications

The proposed mode of consideration of the steel-concrete interaction (Part I) is applied to real-life engineering structures. Two structures recently investigated numerically at Vienna University of Technology are considered: (1) the reinforced concrete (RC) cooling tower III Ptolema?s SES (Greece) and (2) a part of the shotcrete tunnel lining installed at the Lainzer tunnel (Austria). In both examples, the uniaxial fracture criterion used in Part I is replaced by the maximum stress (Rankine) criterion. Together with the Drucker-Prager criterion, which is used for the simulation of compressive failure of concrete/shotcrete, it defines the space of admissible stress states in the framework of multisurface plasticity. For the simulation of early-age fracture of shotcrete, consideration of the steel-concrete interaction presented in Part I of this paper is extended towards young shotcrete. Similar to the benchmark problem investigated in Part I of this paper, several analyses with different degrees of consideration of the steel-concrete interaction are performed. The obtained results give insight into the influence of the steel-concrete interaction on the load-carrying behavior of the investigated structures.     

等径侧向挤压应变分析

对等径侧向挤压变形的应变进行了深入的分析，应用平面纯剪切变形应变分析的结果，得到了等径侧向挤压变形真应变和等效真应变的计算公式，分析了循环等径Ｓ型侧向挤压真空应变和等效真应变的变化规律。     

基于横纵向联合控制的多目标优化车辆跟驰研究

为解决车辆在拥堵环境中因车速波动较大所带来的跟驰平稳性较差、跟踪无效或不安全等问题,提出了基于车辆模型和深度强化学习的多目标优化跟驰方案。首先基于车辆横纵向动力学建立车辆跟驰模型,然后根据车间距误差、速度误差、横向偏差及相对偏航角等,利用深度确定性策略梯度算法得到跟驰车的加速度和转向角,以更平稳安全地控制跟驰车辆。经NGSIM公开驾驶数据集进行测试与验证,该方案可有效地提升跟驰车辆的稳定、舒适与安全性,对保证交通安全和提升道路通行能力具有重要意义。     

环境荷载联合作用下海上风电结构动力响应分析

为研究海上风电结构在复杂的海洋环境中承受环境荷载(风、波、冰、流)的联合作用时,结构产生的剧烈的动力响应问题。文章以三脚架基础海上风电结构为研究对象,采用ANSYS有限元软件建立其整体模型并进行荷载(风、波、流和风、冰、流)联合作用下的静力校核,通过对环境荷载联合作用下的三脚架基础海上风电结构进行瞬态分析,掌握其动力响应的特性及规律。结果表明:三脚架基础结构的一、二阶自振频率均为0.285Hz,在所选风机允许的频率范围内,可以保证整体结构不会与风机转动发生共振;风荷载在风、波、流荷载联合作用下主导控制结构响应的稳态波动,冰荷载在风、冰、流荷载联合作用下主导控制结构的稳态振动过程;塔筒顶端呈现的位移和加速度响应均远大于三脚架基础顶端;环境荷载联合作用下结构动力响应是环境荷载单独作用下动力响应叠加的结果。     

不同变截面桩竖向承载特性的数值分析

基于现场试验,采用Abaqus有限元软件对等截面桩及变截面桩单桩竖向承载力测试实验过程进行数值模拟。结果表明:弹性变形阶段,竖向荷载-沉降曲线呈线性变化趋势,等截面桩比变截面桩桩身沉降较小;塑性屈服阶段,等截面桩与变截面桩单桩承载力几乎一致。变截面位置对桩侧摩阻力沿深度的分布有一定影响,最大侧摩阻力位置根据变截面的位置而变化。变截面桩的平均侧摩阻力较等截面桩的平均侧摩阻力大,变截面桩侧摩阻力效果较等截面桩更有优势。在相同承载力条件下,变截面桩所耗费的材料较等截面少,对于竖向承载特性,变截面桩与等截面桩表现基本一致,因此使用变截面桩能节约工程成本。     

Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases

Neurodegenerative diseases (NDs) including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease are incurable and affect millions of people worldwide. The development of treatments for this unmet clinical need is a major global research challenge. Computer-aided drug design (CADD) methods minimize the huge number of ligands that could be screened in biological assays, reducing the cost, time, and effort required to develop new drugs. In this review, we provide an introduction to CADD and examine the progress in applying CADD and other molecular docking studies to NDs. We provide an updated overview of potential therapeutic targets for various NDs and discuss some of the advantages and disadvantages of these tools.