有色噪声激发下结构随机振动离散分析方法

本文以线性结构体系在白噪声激发下随机振动离散分析方法为基础,对线性结构体系在有色噪声激发下的随机振动离散分析方法进行了研究。给出均值、均方响应的离散递推式.并为了能在计算机上进行实际运算,给出了实用化计算公式,最后用该方法对一结构进行了实际计算,分析了计算结果。     

Oxy210, a Semi-Synthetic Oxysterol,Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization

Inflammatory responses by the innate and adaptive immune systems protect against infections and are essential to health and survival. Many diseases including atherosclerosis, osteoarthritis, rheumatoid arthritis, psoriasis, and obesity involve persistent chronic inflammation. Currently available anti-inflammatory agents, including non-steroidal anti-inflammatory drugs, steroids, and biologics, are often unsafe for chronic use due to adverse effects. The development of effective non-toxic anti-inflammatory agents for chronic use remains an important research arena. We previously reported that oral administration of Oxy210, a semi-synthetic oxysterol, ameliorates non-alcoholic steatohepatitis (NASH) induced by a high-fat diet in APOE*3-Leiden.CETP humanized mouse model of NASH and inhibits expression of hepatic and circulating levels of inflammatory cytokines. Here, we show that Oxy210 also inhibits diet-induced white adipose tissue inflammation in APOE*3-Leiden.CETP mice, evidenced by the inhibition of adipose tissue expression of IL-6, MCP-1, and CD68 macrophage marker. Oxy210 and related analogs exhibit anti-inflammatory effects in macrophages treated with lipopolysaccharide in vitro, mediated through inhibition of toll-like receptor 4 (TLR4), TLR2, and AP-1 signaling, independent of cyclooxygenase enzymes or steroid receptors. The anti-inflammatory effects of Oxy210 are correlated with the inhibition of macrophage polarization. We propose that Oxy210 and its structural analogs may be attractive candidates for future therapeutic development for targeting inflammatory diseases.     

Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism

Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body’s metabolic homeostasis. Studying the signal transduction pathways of the white fat browning might provide novel ideas for the treatment of obesity and alleviation of obesity-related glucose and lipid metabolism disorders. This article aimed to provide an overview of recent advances in understanding white fat browning and the role of BAT in lipid metabolism.     

White Electroluminescence by Supramolecular Control of Energy Transfer in Blends of Organic‐Soluble Encapsulated Polyfluorenes

Here, it is demonstrated that energy transfer in a blend of semiconducting polymers can be strongly reduced by non‐covalent encapsulation of one constituent, ensured by threading of the conjugated strands into functionalized cyclodextrins. Such macrocycles control the minimum intermolecular distance of chromophores with similar alignment, at the nanoscale, and therefore the relevant energy transfer rates, thus enabling fabrication of white‐light‐emitting diodes (CIE coordinates: x = 0.282, y = 0.336). In particular, white electroluminescence in a binary blend of a blue‐emitting, organic‐soluble rotaxane based on a polyfluorene derivative and the green‐emitting poly(9,9‐dioctylfluorene‐alt‐benzothiadiazole ( F8BT ) is achieved. Morphological and structural analyses by atomic force microscopy, fluorescence mapping, µ‐Raman, and fluorescence lifetime microscopy are used to complement optical and electroluminescence characterization, and to enable a deeper insight into the properties of the novel blend.     

Hydrogen‐Bonding‐Assisted Intermolecular Charge Transfer: A New Strategy to Design Single‐Component White‐Light‐Emitting Materials

This study reveals the mechanism of the dual‐emission properties for asymmetrical diphenylsulfone and diphenylketone derivatives. A series of asymmetrical diphenylketone and diphenylsulfone derivatives with dual‐emission properties are designed and synthesized. By single crystal structure analyses, various photophysical studies, and 2D ¹H–¹H NOSEY NMR studies, the lower energy emission bands in the dual‐emission spectra are successfully assigned to hydrogen‐bonding‐assisted intermolecular charge transfer emission. The emission properties of these compounds can easily be tuned in both solid state and solution state by destroying or strengthening the intermolecular hydrogen bonding. In addition, thermally activated delayed fluorescence characteristics for the intermolecular charge transfer emissions are also observed. The control of the intermolecular and intramolecular charge transfers serves as the basis for the generation of the white‐light emission. For compound CPzPO, nearly pure white‐light emission with CIE coordinates of (0.31, 0.32) is easily achieved by precipitation from dichloromethane and hexane mixed solvent system. These results clearly give an insight into the dual‐emission properties and provide a rational strategy for the design and synthesis of single‐component white‐light‐emitting materials and mechanoresponsive light‐emitting materials.     

液晶边光式白色LED背光源的光学设计

通过理论分析与模拟验证,设计和制作了一款采用双侧边光式白光LED作为背光源的26inch(1inch=2.54cm)液晶电视。选用的白光LED结构简单,性能优良。在实际制作中利用高效的驱动电路对白光LED单元进行驱动。模拟结果表明:此结构的白光LED背光源液晶电视亮度均匀性能够达到91%,色度均匀性达到85%,完全满足设计应用要求。     

多芯片阵列组合白光LED封装研究

文章阐述了LED器件的发光原理和芯片电极结构,围绕白光HB-LED的封装工艺,设计单个大功率芯片封装结构并对整个封装工艺进行研究,提出了多芯片阵列组合封装的创新理念,将其应用于多芯片阵列封装模块中。得出HB-LED封装中关键技术问题是提高外量子效率,采用高折射率硅胶减少折射率物理屏障带来的光子损失;采用高热导率的材料,减少由于封装工艺的缺陷带来的界面热阻。     

一种白光LED用绿色荧光粉Ba3Si6O12N2:Eu2+的制备及研究

采用传统高温固相反应法,合成了Ba3－xSi 6O₁₂N₂:xEu²⁺系列荧光粉。X射线衍射(XRD)图谱 分析表明,所有的样品均生成了 Ba₃Si₆O₁₂N₂纯相。激发光谱表明,样品在紫外到蓝光(250～470nm)范围内都可以被有效激发,当激发波长为358nm 时,发射 光谱是Eu²⁺典型的宽带发射,发射峰在495nm附近,属于^4f₇→^4f₆^5d₁能级之间的跃迁,半峰宽覆盖青绿光范围(480～557nm)。 研究了Eu²⁺掺杂浓度对发光性能的影响。结果表明,随着Eu²⁺掺杂量的逐渐增 加 ,发光强度逐渐增大,当x=0.15时,发射 强度达到最大,所对应的发射光谱波峰的波长最小(492nm);当Eu ²⁺的掺杂量继续增加时,发光强度开始减弱,这是由于Eu²⁺间距逐渐减小,非 辐射跃迁几率增加而发生浓度猝灭现象;不同浓度的样品的发光强度 与波长呈相反变化趋势,这与斯托 克斯(Stokes)定律是相符合的。研究结果表明,所合成的Ba₃Si₆O₁₂N 2:Eu²⁺新型绿色荧光粉适合在白光LED中应用。     

VBR Video Source Characterization and a Practical Hierarchical Model

There are many ways to build up traffic models for VBR video sources. A frequently applied methodology is to use mathematical analysis based on realistic assumptions to set up a source model that generates traffic according to a stochastic process. In this case, the critical issue is the validation of the synthetic trace by comparing statistics to results obtained from measurements on the real source. In this paper, we choose a different and more practical approach to model the behavior of the real traffic source. Our model building philosophy is that we analyze and understand what happens with the video information on its way from the ingress to the multimedia terminal to the egress of the network card. Throughout this journey the information is processed by several mechanisms and we build an empirical model step by step based on our measurement-based observations. Besides understanding the traffic generation procedure, statistical analysis of VBR traffic traces captured from a number of video sequences was also carried out in several scenarios. Using the knowledge of encoding, encapsulation and scheduling processes and results of the trace analysis, a hierarchical source model is set up for modeling the multimedia terminal. Thereby our model imitates the generation of video frames and the inner working of each level of protocol hierarchy and tries to reproduce the complex behavior of the real source. We use the leaky bucket analysis for verification of the model in order to capture directly the behavior of the traffic in a queue.