Solid-state single-step synthesis of FeNbO4 perovskite modified nickel foam for electrochemical detection of Creatine phosphokinase in simulated human blood serum

Creatine phosphokinase (CPK-MM), is an important constituent of active muscle, acts as a vital enzyme in intracellular energy transport and is a potential biomarker for diseases like muscular dystrophy (MD), acute renal failure, and muscle damage. Herein, we report a single-step solid-state synthesis of niobium iron oxide(FeNbO₄) modified nickel foam (FeNbO₄/NF) for non-enzymatic detection of CPK-MM in simulated human blood serum. The X-ray diffraction (XRD) reveals an orthorhombic phase formation of FeNbO₄ with (111) family of planes. The FeNbO₄/NF exhibits a low limit of detection (i.e., 0.75 μg/L) and high sensitivity of 1.9 mA/x. cm⁻² (x = μg/L) with a wide linear range of detection ranging from 1 μg/L to 100 μg/mL. This performance of the sensor can be attributed to the excellent electrocatalytic activity of the FeNbO₄ nanomaterial facilitating the effective redox reaction of the CPK. In this mechanism, the presence of oxy functional groups on the surface of FeNbO₄/NF facilitates the interaction between the electrocatalytic active sites of the electrode and the CPK-MM molecules. In addition, this sensor exhibits outstanding selectivity (in presence of different interfering species like ascorbic acid, bovine serum albumin, urea, and uric acid) with good stability as well as reproducibility. The sensor is found successful in the determination of CPK-MM concentration in simulated blood serum samples with good recovery percentages. This efficacy of the as-fabricated electrode demonstrates the FeNbO₄ as a potential platform for various electrochemical-based bioanalytical applications.     

低品位铌矿硫酸焙烧——草酸浸出回收铌的研究

开展了对低品位铌精矿进行硫酸焙烧及草酸浸出研究，考察了不同因素对铌富集效果的影响。结果表明，在硫酸焙烧阶段，在矿物粒径为-150 200目、焙烧温度为200℃和硫酸浓度为80%的条件下，焙烧40min，可使铌精矿中97%以上的铌和90%以上的钙留在渣相，93%以上的铁、锰及钠进入液相；在草酸浸出阶段，在草酸浓度为85%及浸出温度为80℃的条件下，含铌滤渣浸出60min，可使铌浸出率达到98%以上，钙浸出率低于0.6%。     

Nb涂层N36锆合金退火过程中缺陷演化行为的原位透射电镜研究

福岛核事故之后,为锆合金表面涂覆涂层是一种提高核燃料包壳事故容错能力的重要方式。含Nb涂层N36合金辐照后的透射电镜样品利用聚焦离子束进行制备,并通过原位透射电子显微镜研究了氪离子注入后,Nb涂层在退火过程中的气泡生长行为。原位加热结果表明,在退火过程中,界面对气泡的生长存在影响,界面在加热过程中通过对周围气泡的捕获与输送,导致界面附近气泡的生长速度低于远离界面的气泡生长速度。退火后的元素分析表明,辐照与加热均会导致涂层-基体元素扩散距离的增加,其中辐照过程中的元素扩散由热峰混合机制主导。元素的扩散有助于提高涂层的结合性能,并为N36合金提供一定的抗腐蚀能力。