Viscosity Lowering of Difldnisal Fatty Suppository by Hydrogehated Lecithins

Abstract

Diflunisal (Dif), Salicylic Acid Derivative, Is A Nonsteroidal Anti-Inflammatory Drug (Nsaid). Preparation Of Dif Suppositories Which Have A Good Bioavailability Was Attempted. Suppositories Containing Dif (250 Mg, Oral Dose) Were Made By The Fusion Method With Pharmasol B-115 (1050 Mg). However, The Dif Suppository Melt Revealed High Viscosity, And The Finding Was Considered To Be Not Acceptable For Manufacture. Accordingly, The Investigation Was Designed To Select An Optimum Additive Which Is Effective To Lower The Viscosity Of The Suppository Melt. The Viscosity Of The Suppository Melt Was Determined By Utilizing Rotating-Cy1inder Viscometer And Then Bingham Viscosity And Yield Value Were Evaluated. As The Results, Some Lecithins And Magnesium Stearate Were Found To Be Effective To Lower The Viscosity Of Dif Suppository Melts. The Theologically Optimum Formulation Contains Lecinol S-10 (4%) And This Formulation Was Evaluated. In The Evaluation, Physical Properties Such As Melting Point, Hardness, Softening Time, Viscosity Etc., Were Measured By Common Methods. Their Properties Were Satisfactory And Were Practically Stable At 5'c. Dif Itself Was Also Stable In Suppository Melts At 60°C.     

The Decomposition Method For Solving Of A Class Of Singular Two-Point Boundary Value Problems

In this paper, a class of nonlinear singular two-point boundary value problems are solved by using Adomian's decomposition methods. The approximate solution of this problem is calculated in the form of series with easily computable components. Finally, we give a nonlinear numerical example.     

Stability Studies of Ozonized Sunflower Oil and Enriched Cosmetics with a Dedicated Peroxide Value Determination

Ozonized oils have interesting applications in the cosmetic industry and several patents on enriched products were developed in the last years. Ozonides are known for their high reactivity and stability data are required for enriched cosmetic products during storage. In this paper a dedicated determination of Peroxide Value (PV) was performed on ozonized sunflower oil (Neozone 4000) and on some enriched cosmetics, in order to control their stability during storage. The optimal conditions of the PV method were determined, following the decomposition reaction of ozonides with KI utilizing ¹H-NMR and GC/MS techniques.     

The effect of FAR (floor area ratio) regulations on land values: The case of New York

This paper explores the stringency of floor area ratio (FAR), one of the land use regulations in New York, and analyses it by boroughs of New York. Stringency is presented when the regulated height is significantly lower than the free market height and the theoretical approach shows that the elasticity of the land value with respect to FAR is used to estimate the stringency. In particular, we overcome issues in previous studies by constructing a data set using publically available data through new methods. The results show that the FAR stringency in Manhattan is the highest in New York City and the stringency is lower as the distance from the centre of the city increases.     

International Trade

Values of net oil imports(-)/exports for Austria, Belgium, Denmark, Finland, France, Germany, Italy, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland, the United Kingdom, Japan, Canada, the United States and Australia. Updated on a monthly basis. Number of imports for Belgium, France, Germany, Greece, Republic of Ireland, Italy, Netherlands, Portugal, Spain, Sweden, the United Kingdom, and Other EU-15 (EU-15), Norway, Poland, Switzerland, Turkey, and Other Europe (OECD Europe), Canada, Chile, Mexico, and the United States (OECD Western Hemisphere), and Australia, Japan, Republic of Korea, New Zealand, (OECD Asia-Pacific), and Total OECED. Current data for Austria, Belgium, Finland, France, Germany, Greece, Italy, Netherlands, Portugal, Spain, Sweden, the United Kingdom, Other EU-15 (EU-15), Czech Republic, Hungary, Poland, Slovakia, Turkey, and Other Europe (OECD Europe), Canada, Mexico, and the United States (OECD Western Hemisphere), Australia, Japan, Republic of Korea, and New Zealand (OECD Asia-Pacific). Updated on a monthly basis. Current data for principal importers of natural gas and the amount in which they import from United States, Republic of Korea, United Kingdom, France, Japan, Italy, Germany and Spain (Table 19.1). Current data for principal exporters of natural gas and the amount they export to Canada, Trinidad and Tobago, the United States, Netherlands, Norway, Russia, Turkmenistan, Qatar, Algeria, Nigeria, Indonesia, Malaysia and Australia (Table 19.2). Updated on a monthly basis.     

Consumer evaluation of palatability characteristics of a beef value-added cut compared to common retail cuts

The objectives of this study were to educate consumers about value-added beef cuts and evaluate their palatability responses of a value cut and three traditional cuts. Three hundred and twenty-two individuals participated in the beef value cut education seminar series presented by trained beef industry educators. Seminar participants evaluated tenderness, juiciness, flavor, and overall like of four samples, bottom round, top sirloin, ribeye, and a value cut (Delmonico or Denver), on a 9-point scale. The ribeye and the value cut were found to be similar in all four attributes and differed from the top sirloin and bottom round. Correlations and regression analysis found that flavor was the largest influencing factor for overall like for the ribeye, value cut, and top sirloin. The value cut is comparable to the ribeye and can be a less expensive replacement.     

Value drivers of blockchain technology: A case study of blockchain-enabled online community

There is growing recognition that blockchain technology has significant potential to alter how organizations and people work and communicate. However, theoretical guidance concerning how organizations leverage blockchain technology to enhance value creation for users is still limited. Grounded in the socio-technical perspective and leveraging the rich data obtained from case analyses of blockchain-enabled online communities, this paper develops a theoretical model to identify the core value drivers that blockchain enables for online communities. The core value drivers include: a reputation-value system, data ownership mechanisms, and verification & tracking mechanisms. Our findings suggest that these three value drivers enhance value creation of online communities by motivating participation and protecting contributions.     

Optimal design of hybrid power generation system and its integration in the distribution network

The inability of conventional energy sources to fully meet the rapidly increasing energy demands in today’s world has led to the growing importance of hybrid power generation systems that incorporate renewable energy sources. This work proposes an optimally designed multi-source standalone hybrid generation system comprising of photovoltaic panels, wind turbine generators, batteries and diesel generator. This design aims at minimizing emissions and cost, expressed in the form of the Net Present Value (NPV) of the system, while simultaneously maximizing its Energy Index of Reliability (EIR). The designed hybrid power generation system is further integrated into the distribution system as a Distributed Generation (DG); this is to optimally improve the performance of the distribution system by minimizing the total losses and the total voltage deviation of the distribution system. The combined cost and emissions incurred due to the energy purchased from the grid and the energy generated by DG are also reduced. For this purpose an improvised Multi-Objective Particle Swarm Optimization (MOPSO) algorithm is developed taking care of contradicting objectives. The proposed optimization algorithms are implemented using MATLAB for a standard IEEE 69-bus distribution system, using an hour-wise annual data of Spain. The location and size of DGs and the type and number of each generating source of the hybrid system are considered as decision variables. The effectiveness of the proposed optimal design using the improvised MOPSO algorithm is established in comparison with Improved Hybrid Optimization by Genetic Algorithm (i-HOGA) results.     

Value creation in software service platforms

In order to benefit from operating an IT service platform (e.g., SaaS platform), platform providers need to find a way to keep their existing users and application services active sources of value. However, the understanding of how to achieve that is limited due to the newness of this kind of business. This paper investigates whether all stakeholders of the platform ecosystem can generate sufficient value when participating in the platform. As stakeholders, we consider application service users, service developers, and service platform providers. We also analyse the interrelationship between these stakeholders. The analysis outcome is a value creation model that allows the calculation of the stakeholders’ values. The model also helps inferring the relative impact of different factors on the evolution of values of the software service platform stakeholders. Our simulation results confirm that all stakeholders of a service platform mainly benefit from a growing installed base of application users. However, in a mature market, a large service variety mainly benefits the service platform provider, while the other stakeholders obtain a reduced increase in their benefits. In particular, the utility growth of application users becomes constrained as the benefit from new connections with other users decreases and the number of new services used decreases. Similarly, the revenue of service developer decreases, making service development less profitable. Therefore, we can state that not only a large fraction of the value creation goes to the platform provider but also that the software service ecosystem can collapse, if no mutually beneficial pricing of services is implemented.