铁路桥梁横向振动模拟及适应快速行车结构型式的研究

针对铁路提速后出现的上承式简支钢板梁桥跨中横向振幅过大的问题,以羊楼司桥(L=32m单跨上承式简支钢板梁桥)为例进行实桥检测和数值模拟,建立车辆、线路、桥梁三者的联合模型,考虑轮轨接触力,应用MSC/DYTRAN大型结构分析程序进行车线桥动力相互作用的仿真分析。研究揭示我国用量最多的C62型货车以70∽80km/h的速度空载通过时,该跨度的钢板梁桥发生横向谐振的机理。此外,用该方法对32m跨长的组合梁结构进行桥梁动力特性及列车走行性分析,表明该结构满足提速货车和高速电动旅客列车走行的要求。研究结果对我国高速铁路桥梁建设和既有桥梁的改造具有积极意义。     

Heterogeneous chain propagation in low-pressure flames

An analysis of papers on hydrogen combustion at low pressures is performed, which refines the contribution of the catalytic reactions on the reactor wall to the gas-phase part of the process. A new model for the heterogeneous loss of active reaction centers was proposed and tested experimentally to explain inconsistencies that occur in some papers. In this model, the diffusion region of chain termination is formed under standard experimental conditions in vacuum oxyhydrogen flames at a reactor gas pressure a thousand times lower than the boundary pressure postulated by the previous models as the pressure below which the diffusion region of chain termination cannot be formed. __________ Translated from Fizika Goreniya i Vzryva, Vol. 42, No. 2, pp. 10–18, March–April, 2006.     

靶向抗癌药格列卫与其治疗白血病疗效监测

Gleevec是抑制致癌的融合蛋白BCR-ABL的一种分子靶向治疗药物,BCR-ABL是一种与慢性髓细胞性白血病(CML)有关的酪氨酸激酶抑制剂。用Gleevec选择性地抑制BCR-ABL活性在治疗CML中显示出很好的效果,特别是在CML慢性期,因此,监测疗效非常重要。现就Gleevec的研究进展及如何监测其在CML中的疗效作一简单综述。     

马尔可夫链在企业经济预测上的应用

为了科学的预测企业所关心的各项经济指标 ,以便为企业的未来做出正确的决策方案 ,需用适当的数学模型和方法对企业的经济活动进行定量的研究 .基于经济活动的复杂、多变性及带有许多随机性因素的特点 ,针对这两种常见的经济问题 ,分别建立了相应的马尔可夫链模型 .应用马尔可夫链的相关理论、巧妙的构造转移概率矩阵 ,只通过简单的矩阵运算 ,便迅速解决问题 .实例表明 ,马尔可夫链模型及方法在企业经济活动分析中是可行和适用的 ,可广泛用于解决企业中常见的预测及决策问题 .     

Frequency weighting for the evaluation of steering wheel rotational vibration

The human perception of rotational hand–arm vibration has been investigated by means of a test rig consisting of a rigid frame, an electrodynamic shaker unit, a rigid steering wheel, a shaft assembly, bearings and an automobile seat. Fifteen subjects were tested while seated in a driving posture. Four equal sensation tests and one annoyance threshold test were performed using sinusoidal excitation at 18 frequencies in the range from 3 to 315 Hz. In order to guarantee the generality of the equal sensation data, the four tests were defined to permit checks of the possible influence of three factors: reference signal amplitude, psychophysical test procedure and temporary threshold shift caused by the test exposure. All equal sensation tests used a reference sinusoid of 63 Hz at either 1.0 or 1.5 m/s² r.m.s. in amplitude. The four equal sensation curves were similar in shape and suggested a decrease in human sensitivity to hand–arm rotational vibration with increasing frequency. The slopes of the equal sensation curves changed at transition points of approximately 6.3 and 63 Hz. A frequency weighting, called W_s, was developed for the purpose of evaluating steering wheel rotational vibration. The proposed W_s has a slope of 0 dB per octave over the frequency range from 3 to 6.3 Hz, a slope of −6 dB per octave from 6.3 to 50 Hz, a slope of 0 dB per octave from 50 to 160 Hz and a slope of −10 dB per octave from 160 to 315 Hz. W_s provides a possible alternative to the existing W_h frequency weighting defined in International Standards Organisation 5349-1 (2001) and British Standards Institution BS 6842 (1987).

Relevance to industry

For the manufacturers of tyres, steering systems and other vehicular components the proposed W_s frequency weighting provides a more accurate representation of human perception of steering wheel rotational vibration than the W_h weighting of ISO 5349-1 and BS6842.     

过程链管理--用于制定和管理转型组织的工具

在当今企业环境日益复杂而活跃的背景条件下，企业需要不断进行重组和迅速转型。这要求企业要具备更强的适应性和更高的灵活性。为了确保实现这些动态的要求，企业必须制定和实施新型的组织形式。本文介绍过程链管理——一种面向过程进行转型的工具。本文首先简要说明了过程链管理应用的工具、过程链管理的任务和构造。它的出发点是由行动、结构、资源、和指挥所组成的过程链管理。在第二步骤中，重点阐述了客户取向这个过程链管理中最重要的取向量。总体来说，整个价值创造链及与此相关的内部交换关系都具有重要意义。在对过程链管理的方法进行了说明以后，提出了一个应用实例，该实例不仅描述了垂直重构，也对水平重构进行了描述。     

纳米SiO_2与有机物分子的亲和性和分散性

介绍纳米SiO2的合成和粒子表面的粗糙形貌以及纳米粒子链具有类似高分子链的弹性力学属性,研究纳米SiO2的亲合性,探讨亲合性对纳米SiO2的分散、改性、应用的影响。研究表明,在极性外加剂(如乙二胺、乙二醇、PEG、PDMS、PTHF、PMMA、PBMA等)存在的情况下,纳米SiO2的弹性粒子链和硅烷醇对SiO2的分散和改性具有显著的影响。带有大烷基侧链的高分子链与SiO2表面的亲合能较低,而带有官能团的高分子链与SiO2表面具有较高的亲合性。     

对等张力链条机构设计的再思考

为解决震源在振动器提升后链条与销轴的断裂问题,应采用等张力原理对链条提升机构进行改进设计。经野外实践证明,这种机构基本上能够满足野外工作的要求。本文对目前所采用的机构形式可能存在的改进设计进行了分析。     

APPLICATION OF THE POLYMERASE CHAIN REACTION TO THE RAPID ANALYSIS OF BREWERY YEAST STRAINS

The rapid discrimination of closely-related Saccharomyces cerevisiae strains can pose a significant problem to breweries, in particular where closely related strains are being used simultaneously to manufacture different products. In this study, two PCR approaches have been examined to assess their usefulness for the discrimination of brewery ale and lager yeast strains. PCR using arbitrary primers (RAPD PCR) was found unsuitable for such an application since the DNA profiles generated from brewery strains were generally found to be identical, due presumably to the close genetic relatedness of these yeasts. In contrast, PCR using δ sequence primers could rapidly differentiate between many ale and lager strains and characteristic profiles for these were generated. This method could also be applied directly to yeasts isolated from brewery worts or from active dried yeast preparations. Results of such analyses were available within the working day.     

基于分形理论的供应链管理模型分析

为了克服日益复杂的供应链问题,在分形理论的基础上介绍了分形供应链的概念和特点,认为分形供应链所具有的自相似、自组织、自优化等特点可以很好地提高供应链的灵活性,增强适应环境的能力.在此基础上进一步研究了分形供应链的结构模型和运作模型,探讨了其现实意义.