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排序方式: 共有3105条查询结果,搜索用时 156 毫秒
81.
Julia Welzenbach Christiane Neuhoff Hanna Heidt Mehmet Ulas Cinar Christian Looft Karl Schellander Ernst Tholen Christine Gro?e-Brinkhaus 《International journal of molecular sciences》2016,17(9)
The aim of this study was to integrate multi omics data to characterize underlying functional pathways and candidate genes for drip loss in pigs. The consideration of different omics levels allows elucidating the black box of phenotype expression. Metabolite and protein profiling was applied in Musculus longissimus dorsi samples of 97 Duroc × Pietrain pigs. In total, 126 and 35 annotated metabolites and proteins were quantified, respectively. In addition, all animals were genotyped with the porcine 60 k Illumina beadchip. An enrichment analysis resulted in 10 pathways, amongst others, sphingolipid metabolism and glycolysis/gluconeogenesis, with significant influence on drip loss. Drip loss and 22 metabolic components were analyzed as intermediate phenotypes within a genome-wide association study (GWAS). We detected significantly associated genetic markers and candidate genes for drip loss and for most of the metabolic components. On chromosome 18, a region with promising candidate genes was identified based on SNPs associated with drip loss, the protein “phosphoglycerate mutase 2” and the metabolite glycine. We hypothesize that association studies based on intermediate phenotypes are able to provide comprehensive insights in the genetic variation of genes directly involved in the metabolism of performance traits. In this way, the analyses contribute to identify reliable candidate genes. 相似文献
82.
Urban cellular automata (CA) models are broadly used in quantitative analyses and predictions of urban land-use dynamics. However, most urban CA developed with neighborhood rules consider only a small neighborhood scope under a specific spatial resolution. Here, we quantify neighborhood effects in a relatively large cellular space and analyze their role in the performance of an urban land use model. The extracted neighborhood rules were integrated into a commonly used logistic regression urban CA model (Logistic-CA), resulting in a large neighborhood urban land use model (Logistic-LNCA). Land-use simulations with both models were evaluated with urban expansion data in Xiamen City, China. Simulations with the Logistic-LNCA model raised the accuracies of built-up land by 3.0%–3.9% in two simulation periods compared with the Logistic-CA model with a 3 × 3 kernel. Parameter sensitivity analysis indicated that there was an optimal large window size in cellular space and a corresponding optimal parameter configuration. 相似文献
83.
Mariam Alhattab 《分离科学与技术》2017,52(12):2002-2016
Microalgae biomass has great potential for being used as feedstock for the sustainable production of biodiesel, as it is able to produce 7–31 times more oil than the top terrestrial crop. It is a green alternative to the currently utilized energy sources as it can reduce CO, CO2 and hydrocarbon emissions. However, downstream processing costs for the dilute biomass are a major challenge. Foam flotation has been recently investigated for the recovery of microalgae cells from dilute liquid suspensions. A number of variables on the effectiveness of foam flotation for microalgae have been investigated, which include surfactant type and concentration, cell concentration, pH, hydrophobicity, time, growth stage, flow rate, ionic strength, alkalinity, temperature, bubble size, and column size. It appears to be a promising method for the recovery of algae for biofuel production, as a result of the high removal recoveries, good enrichment ratios, ability to process large volumes of biomass, and its ease of operation. However, literature on this subject is scarce, and there are research gaps that should be investigated including characterization of microalgae cells and impact on foam separation and the effect of surfactant as a treatment prior to lipid extraction. 相似文献
84.
A new approach to obtain a volumetric discretization from a T-spline surface representation is presented. A T-spline boundary zone is created beneath the surface, while the core of the model is discretized with Lagrangian elements. T-spline enriched elements are used as an interface between isogeometric and Lagrangian finite elements. The thickness of the T-spline zone and thereby the isogeometric volume fraction can be chosen arbitrarily large such that pure Lagrangian and pure isogeometric discretizations are included. The presented approach combines the advantages of isogeometric elements (accuracy and smoothness) and classical finite elements (simplicity and efficiency).Different heat transfer problems are solved with the finite element method using the presented discretization approach with different isogeometric volume fractions. For suitable applications, the approach leads to a substantial accuracy gain. 相似文献
85.
Clment De Saint Jores Clment Brandel Najla Gharbi Morgane Sanselme Pascal Cardinael Grard Coquerel 《化学工程与技术》2019,42(7):1500-1504
Since eutomer and distomer show different biological effects, access to pure enantiomers is essential. Preferential enrichment is a relatively new process of chiral resolution developed in the 90s. Extension of its scope was attempted with tryptophan ethyl ester hydrochloride. This salt meets one of the most important requirements for preferential enrichment, namely, a larger solubility for the pure enantiomers with reference to the racemic compound. But, due to the absence of a solid solution, this salt cannot perform preferential enrichment. This impossibility was endorsed by semi‐empirical molecular modeling. 相似文献
86.
Prasanta Das Samir Charola Milan Dinda Himanshu Patel Subarna Maiti 《International Journal of Hydrogen Energy》2017,42(21):14471-14484
Hydrogen can be cited as prospective source of clean power. In this work hydrogen rich syn-gas generated from the agro-waste, empty cotton bolls was injected into an IC engine in continuous mode along with gasoline. At the air-fuel ratio of 23.40, specific fuel consumption of 0.35 kg kWh?1, the engine could be operated with higher efficiency than with gasoline alone. A distinct reduction in emission characteristics could also be seen. Empty cotton bolls derived after removal of cotton from the flower in field, was first studied for fuel properties. The reasonably high heating value (HHV) of 17.54 MJ kg?1 suggested that it could be a precursor to hydrogen via two stepped thermo-chemical process. The first step involved slow pyrolysis of the biomass at 500 °C for 60 min at a heating rate of 10 °C min?1 yielding 39.71% bio-char by weight. The C, H, N, S and O contents of the produced bio-char was 59.91, 2.91, 0.72, 0.47 and 35.99% respectively and its HHV was 26.7 MJ kg?1. Steam gasification of this bio-char, at 700 °C and water flowrate of 7 mL min?1 exhibited maximum hydrogen yield of 67.42% (v/v) in the syn-gas mixture. Subsequent enrichment of the gas using ethanolamine/ethylene diamine and KMnO4 solutions resulted in more than 90% (v/v) hydrogen in the combustible gas mixture and the test engine could be effectively operated. 相似文献
87.
渤海海域辽西构造带S型走滑转换带特征及控藏作用定量表征 总被引:1,自引:0,他引:1
S型走滑转换带是走滑环境下广泛发育的一类构造。以往的研究认识多集中在对走滑转换带类型划分的探讨上,缺乏对其控藏作用的精细研究。本次研究利用渤海海域辽东湾地区连片三维地震资料,结合油气田实例,运用统计学方法分析了辽西构造带S型走滑转换带的控藏作用。辽西带新生代构造变形总体表现为NE向伸展构造系统和NNE向右旋走滑构造系统的叠加构造变形,S型走滑转换带可分为增压段和释压段两大类。按照走滑转换带演化阶段的不同,将增压段进一步细分为压扭低凸起段、平缓增压段和强烈增压段等3个亚类。将释压段同样细分为纺锤形浅凹、平缓释压段和菱形释压段等3个亚类。将走滑断裂末端发育的转换带归纳为增压型或释压型马尾扇。应用S型走滑转换带“油气富集指数”的分析方法,论证了S型走滑转换带弯曲度与走滑调节断层活动性具有正相关性,并成功应用于辽西凹陷南次洼旅大5-2北油田成藏分析工作中,为勘探决策提供了定量化依据。 相似文献
88.
For a distributed parameter system with an input delay in the boundary, a feedback control law is presented by means of the backstepping method. The square integrability of input signal is verified based on the target system. Then, the boundedness and invertibility of the corresponding backstepping transformation are proved under the regularity of system and the admissibility of feedback operator. Thus, the resulting closed-loop system is shown to be exponentially stable. Finally, as an application, a numerical simulation of a one-dimensional Schrödinger equation with a delay input is carried out, and the simulation results demonstrate the effectiveness of the suggested control law. 相似文献
89.
根据矿井地质条件,确定了七五生建煤矿北七采区701工作面的火成岩侵入范围。通过实验室测定,分析了火成岩侵入对煤层瓦斯赋存的影响,结果表明:火成岩侵入区煤体吸附瓦斯的能力相对于未侵入区更强;通过现场实际测定,得到火成岩侵入对矿井瓦斯涌出的影响规律。掘进巷道施工时,在掘进至火成岩侵入区域前,瓦斯浓度上升趋势不明显;火成岩侵入后,瓦斯涌出呈剧增趋势;在经过火成岩侵入区域后,瓦斯浓度呈缓慢下降趋势。根据对瓦斯数据的统计、分析,通过改变通风条件、调控瓦斯涌出量,加强监测监控等措施,较好地解决了矿井瓦斯治理问题。 相似文献
90.
《Journal of Nuclear Science and Technology》2013,50(4):361-366
It is strongly demanded to control reactivity for safety and steady operation of nuclear reactor. Fissile enrichment should be, therefore, accurately managed in order to carry out it. A concept of physical accounting method for adjusting fissile enrichment is very useful to manage plutonium content and to control reactivity of nuclear reactor where plutonium is used as main fissile material. The basis of the concept is shown in this paper together with the result of the application to typical prototype fast breeder reactor (FBR). The rationality for adopting the method is also quantitatively shown in this paper. 相似文献