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11.
Number entry is a ubiquitous activity and is often performed in safety- and mission-critical procedures, such as healthcare, science, finance, aviation and in many other areas. We show that Monte Carlo methods can quickly and easily compare the reliability of different number entry systems. A surprising finding is that many common, widely used systems are defective, and induce unnecessary human error. We show that Monte Carlo methods enable designers to explore the implications of normal and unexpected operator behaviour, and to design systems to be more resilient to use error. We demonstrate novel designs with improved resilience, implying that the common problems identified and the errors they induce are avoidable. 相似文献
12.
Sundaram Vickram Karunakaran Rohini Subramanian Srinivasan David Nancy Veenakumari Kumar Archana Krishnan Anbarasu Palanivelu Jeyanthi Sundaram Thanigaivel Govindarajan Gulothungan Nanmaran Rajendiran Padmalayam Sadanandan Srikumar 《International journal of molecular sciences》2021,22(4)
Zinc (Zn), the second-most necessary trace element, is abundant in the human body. The human body lacks the capacity to store Zn; hence, the dietary intake of Zn is essential for various functions and metabolism. The uptake of Zn during its transport through the body is important for proper development of the three major accessory sex glands: the testis, epididymis, and prostate. It plays key roles in the initial stages of germ cell development and spermatogenesis, sperm cell development and maturation, ejaculation, liquefaction, the binding of spermatozoa and prostasomes, capacitation, and fertilization. The prostate releases more Zn into the seminal plasma during ejaculation, and it plays a significant role in sperm release and motility. During the maternal, labor, perinatal, and neonatal periods, the part of Zn is vital. The average dietary intake of Zn is in the range of 8–12 mg/day in developing countries during the maternal period. Globally, the dietary intake of Zn varies for pregnant and lactating mothers, but the average Zn intake is in the range of 9.6–11.2 mg/day. The absence of Zn and the consequences of this have been discussed using critical evidence. The events and functions of Zn related to successful fertilization have been summarized in detail. Briefly, our current review emphasizes the role of Zn at each stage of human reproduction, from the spermatogenesis process to childbirth. The role of Zn and its supplementation in in vitro fertilization (IVF) opens opportunities for future studies on reproductive biology. 相似文献
13.
This work is devoted to the stress–strain state of isotropic double curved shell with defect system. The construction is weakened by two non-through thickness (internal) cracks of different length and by a circular hole located between cracks. In this study we use the line-spring model. Within the framework of this model cracks are modeled as mathematical cuts of shell’s middle surface. This leads to a two-dimensional problem. The problem is reduced to a system of eight boundary integral equations. To ensure the uniqueness of solution an additional equation is added. In the numerical solution of the problem special quadrature formulas for singular integrals of Cauchy type and the finite difference method are applied. The influence of defects on each other for double curved shell has been investigated. The given theoretical results can be used for the calculation of structural elements with holes, cracks on the strength and fracture toughness in various branches of engineering. 相似文献
14.
The workforce ageing phenomenon is recently affecting most of the Organisation for Economic Co-operation and Development (OECD) member countries, due to a general ageing of their populations and a higher average retirement age of the workforce. In this paper, the topic of ageing workforce management is addressed from a production research standpoint, with the aim of understanding how older workers can be supported and involved in a manufacturing system. First, the current state of the art related to the ageing workforce in production systems is presented. This is structured according to four main topics: (1) analysis and evaluation of ageing workers’ functional capacities, (2) consideration of ageing workers’ capacities in industrial system modelling and management, (3) analysis and exploitation of ageing workers’ expertise, (4) acknowledgement, analysis, design and integration of supporting technologies. Next, the discussion on the impact of the ageing workforce on manufacturing systems’ performances leads to the comparison of some technological advances that are related to the Industry 4.0 paradigms. Finally, a future research agenda on this topic is proposed, based on the same topics classification proposed for the literature analysis. Five different research areas are derived, suggesting future directions for appropriate research concerning the employ of older workers in production environments. 相似文献
15.
Sophia X. Sui Lana J. Williams Kara L. Holloway-Kew Natalie K. Hyde Julie A. Pasco 《International journal of molecular sciences》2021,22(1)
Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and reduced neurological drive. Cognitive decline refers to diminished or impaired mental and/or intellectual functioning. Contracting skeletal muscle is a major source of neurotrophic factors, including brain-derived neurotrophic factor, which regulate synapses in the brain. Furthermore, skeletal muscle activity has important immune and redox effects that modify brain function and reduce muscle catabolism. The identification of common risk factors and underlying mechanisms for sarcopenia and cognition may allow the development of targeted interventions that slow or reverse sarcopenia and also certain forms of cognitive decline. However, the links between cognition and skeletal muscle have not been elucidated fully. This review provides a critical appraisal of the literature on the relationship between skeletal muscle health and cognition. The literature suggests that sarcopenia and cognitive decline share pathophysiological pathways. Ageing plays a role in both skeletal muscle deterioration and cognitive decline. Furthermore, lifestyle risk factors, such as physical inactivity, poor diet and smoking, are common to both disorders, so their potential role in the muscle–brain relationship warrants investigation. 相似文献
16.
Online gaming addiction has been increasingly recognized as a mental disorder. However, the predictive factors that lead to online gaming addiction are not well established. The aim of this study was to identify factors that may influence the development of online gaming addiction. A total of 263 patients with problematic online gaming addiction (255 males (97%) and 8 females (3%), age: mean = 20.4 ± 5.8 years) and153 healthy comparison subjects (118 males (77%) and 35 females (23%), age: 21.2 ± 5.5 years, range) were recruited for participation in the current study. Hierarchical logistic regression analyses among each set of variables were conducted. Individual factors (sex and age), cognitive factors (IQ and perseverative errors), psychopathological conditions (ADHD, depression, anxiety, and impulsivity), and social interaction factors (family environment, social anxiety, and self-esteem) were evaluated in a stepwise fashion. All four factors were associated with online gaming addiction, with psychopathological conditions being the strongest risk factors for the addiction. Individual factors, psychological factors, and social interactions were associated with the development of pure online gaming addiction. As before, psychological factors (attention, mood, anxiety and impulsivity) were the strongest risk factors for online gaming addiction in patients with pure online gaming addiction. Psychopathologies, including ADHD and depression, were the strongest factors associated with the development of online gaming addiction in individuals. 相似文献
17.
18.
Aircraft maintenance organisation is a complex socio-technical setup, where human factors influence the quality of aircraft maintenance service. Maintenance service quality is assessed based on the commitment of management and its ability to provide suitable facility, tools, spares and manpower supported with comfortable environment and maintenance procedures. Assessment of the service quality of the aircraft maintenance organisation is a complex process. Airlines, regulators, insurance companies and other agencies need decision support system, to assess the performance of a maintenance organisation. This paper provides criteria and scientific approach for assessing the maintenance organisation; it presents a methodology of applying Analytical Hierarchy Process to prioritise the key functions and to rank the maintenance organisations under study. The study has established that maintenance service quality in airline is directly correlated to its fleet size. 相似文献
19.
介绍了PET熔体长距离输送工艺流程,重点分析易对PET熔体输送带来不利影响的因素,如熔体压力降、停留时间、管道粗糙度、焊缝品质等,并针对熔体输送的不利因素,提出了相应的解决方案,对熔体直纺设计、实践提供必要的参考。 相似文献
20.
基于深度学习的人体姿态估计方法旨在通过构建合适的神经网络,直接从二维的图像特征中回归出人体姿态信息。主要按照2D人体姿态估计到3D人体姿态估计的顺序,并从单人检测与多人检测、稀疏的关节点检测与密集的模型构建等方面,对近年来基于深度学习的人体姿态估计方法进行系统介绍,从而初步了解如何通过深度学习的方法得到人体姿态的各个要素,包括肢体部件的相对朝向和比例尺度、骨骼关节点的位置坐标和连接关系,甚至更为复杂的人体蒙皮模型信息。最后,对当前研究面临的挑战以及未来的热点动向进行概述,清晰地呈现出该领域的发展脉络。 相似文献