A piecewise analysis method to stability analysis of linear continuous/discrete systems with time‐varying delay

The delay‐dependent stability problem of linear continuous/discrete systems with time‐varying delay is investigated based on a piecewise analysis method (PAM). In the method, the variation interval of the time delay is firstly divided into several subintervals. By checking the variation of the Lyapunov functional in every subinterval, some new delay‐dependent stability criteria are derived. Several numerical examples show that our method can lead to much less conservative results than those in the existing references. Moreover, when the number of the divided subintervals increases, the corresponding criteria can provide an improvement on the results. Copyright © 2008 John Wiley & Sons, Ltd.     

基于改进的基因表达式编程算法在作业车间调度问题中的应用

文章提出一种新颖的方法一改进的基因表达式编程算法来求解作业车间调度问题。作业车间调度问题是许多实际生产调度问题的简化模型,基因表达式编程算法结合了遗传算法和遗传编程的优点,具有更强的解决问题能力,对基因表达式编程算法进行改进使其在作业车间调度问题的应用上更加有效;最后应用一个实例来验证提出方法的有效性。     

佛手凉果加工过程中功能性成分与抗氧化性分析

佛手凉果是具有功能特性的岭南特色凉果品种,探究佛手凉果制作过程中功能性成分及其体外抗氧化活性变化规律,可为佛手凉果产业工艺优化与改良提供依据。结果表明,加工提高了佛手中总酸、多糖、黄酮和膳食纤维含量,导致多酚含量下降。制作过程中,1,1－二苯基－2－三硝基苯(DPPH)自由基、2,20 -联氮- 2 -三硝基苯肼(ABTS)自由基清除能力和铁离子还原抗氧化能力(Ferric Reducing Antioxidant Power, FRAP)呈现先下降后上升的趋势,效果分别是新鲜佛手的1.35倍、1.57倍和2.16倍。总黄酮与FRAP之间呈现极显著相关性(P＜0.01);与DPPH、ABTS呈显著相关性(P＜0.05);有机酸、总多糖分别与ABTS和FRAP之间相关性(P＜0.05)。为此,在佛手凉果的制作过程中,糖制和干燥工艺对功能性成分的转化与浓缩起关键作用,可作为工艺优化的重点。     

脱水过程中无核白葡萄转录组测序及膜脂降解代谢中关键基因的筛选

该研究以吐鲁番地区无核白葡萄为试验材料,在25 ℃常温和30 ℃热风干燥后,取失水25%、50%时褐变和未褐变的样品。利用转录组测序技术筛选出膜脂降解代谢相关的关键基因,并利用实时荧光定量PCR技术对其进行验证,研究结果显示,转录组测序共获得了11.63亿的clean data,当无核白失水50%时未褐变与褐变的相比,在快速脱水组筛选出718个差异表达基因,慢速脱水组2 259个。将上述基因进行GO功能富集和KEGG富集分析后,筛选出43个膜脂代谢相关的差异基因,归类于5种代谢途径。从已获得的差异基因中最终筛选出乙醛脱氢酶7B4（Aldehyde Dehydrogenase7B4,ALDH7B4）、双半乳糖甘油二酯合成酶1（Digalactose Diglycerol Synthetase1,DGD1）、脂氧合酶（Lipoxygenase,LOX）、磷脂磷酸水解酶2（Lipid Phosphate Phosphatase2,LPP2）、二酰基甘油激酶5（Diacylglycerol Kinase5,DGK5）、非特异性磷脂酶C4（Non-specific Phospholipase C4,NPC4）、磷脂酶Dα1（Phospholipase Dα1,PLDα1）7个膜脂代谢相关的关键基因,经qRT-PCR验证,基因表达趋势与转录组测序结果基本一致。结果表明,膜脂降解代谢相关基因表达量变化对无核白脱水褐变有一定影响。     

Peptidyl Virus-Like Nanovesicles as Reconfigurable “Trojan Horse” for Targeted siRNA Delivery and Synergistic Inhibition of Cancer Cells

The self-assembly of peptidyl virus-like nanovesicles (pVLNs) composed of highly ordered peptide bilayer membranes that encapsulate the small interfering RNA (siRNA) is reported. The targeting and enzyme-responsive sequences on the bilayer's surface allow the pVLNs to enter cancer cells with high efficiency and control the release of genetic drugs in response to the subcellular environment. By transforming its structure in response to the highly expressed enzyme matrix metalloproteinase 7 (MMP-7) in cancer cells, it helps the siRNA escape from the lysosomes, resulting in a final silencing efficiency of 92%. Moreover, the pVLNs can serve as reconfigurable “Trojan horse” by transforming into membranes triggered by the MMP-7 and disrupting the cytoplasmic structure, thereby achieving synergistic anticancer effects and 96% cancer cell mortality with little damage to normal cells. The pVLNs benefit from their biocompatibility, targeting, and enzyme responsiveness, making them a promising platform for gene therapy and anticancer therapy.     

Adaptive control for a class of nonlinear systems with time-varying delays in state and input

This paper is concerned with the adaptive stabilization problem of uncertain input delayed systems.A solution to this problem is given for a class of uncertain nonlinear systems with time-varying delays in both state and input.An adaptive asymptotically stabilizing controller,which can guarantee the stability of the closed-loop system and the convergence of the original system state,is designed by means of the Lyapunov-Krasovskii functional stability theory combined with linear matrix inequalities (LMIs) an...     

Absolute Stability of Nonlinear Systems with Two Additive Time-varying Delay Components

In this paper, we present a new sufficient condition for absolute stability of Lure system with two additive time-varying delay components. This criterion is expressed as a set of linear matrix inequalities (LMIs), which can be readily tested by using standard numerical software. We use this new criterion to stabilize a class of nonlinear time-delay systems. Some numerical examples are given to illustrate the applicability of the results using standard numerical software.     

EPA功能安全协议的研究与实现

现场总线在通信传输过程中,会受到各种通信故障的影响,而现场总线与功能安全的结合可降低这种影响。该文描述EPA功能安全通信模型,针对通信传输过程中可能出现的通信错误,采用时间戳、序列号、CRC校验等功能安全通信技术。给出EPA功能安全协议层的报文结构,阐述功能安全协议层的具体实现过程。     

论数字图书馆系统中WEB服务器性能优化的方法

由于在数字图书馆系统中流通着的大多是数字化的索引、文摘、全文、图像或音频视频等多媒体信息,对Web服务器性能有着较高的要求.结合实际工程的经验,从硬件实现手段(缓存服务器、均衡负载设备、Web双机镜像等)和软件实现手段(多层软件结构设计、应用部署等)等两个大方面论述如何提高Web服务器性能,以便使用户能够更快捷、高效、安全地使用数字图书馆应用系统.     

Exploring the potential of boron-doped nanographene as efficient charge transport and nonlinear optical material: A first-principles study

Owing to their excellent electrochemical properties, graphenes found applications in several fields ranging from semiconductors, solar cells, field effect transistors, and nanoscale electronic devices as well as in nonlinear optical (NLO) applications. The structural features, electro-optical, charge transport and nonlinear optical properties of the boron-doped graphene (BG) compound 1 were studied using density functional theory methods The BG compound comprises a central electron deficient site of boron atoms, which can serve as electron acceptor while terminal alkoxy groups as donors leading to powerful donor-π-acceptor (D-π-A) configuration. The experimental crystal structure was successfully reproduced by optimized ground state geometry at PBE0/6-311G* level of theory for isolated molecule. The experimental lattice parameters, geometries, crystal presentation and alignment of molecules in the unit cells as well as their packing orientation of BG compound 1 was also efficiently reproduced by applying periodic boundary conditions (PBC) at PBE level. The comprehensive intramolecular charge transfer (CT) was realized from terminal rings of the HOMO to the electron deficient sites of boron atoms of the LUMO. The nature of BG compound 1 might be more towards hole transport even though its hole reorganization energy is twice than that of the electron one due to the significant higher hole transfer integral values. The superior hole transfer integrals and intrinsic mobility values of the BG compound 1 might lead remarkable hole transport contender as compared to many other organic materials. The narrow band gap, density of states profile, dielectric function, uniform conductivity functions and noteworthy electronic as well as CT properties revealed that the BG compound 1 might be proficient optoelectronic contestant having intermolecular CT as well as intramolecular CT with optimal stability. A comparison of static third-order polarizability <γ> of BG compound 1, as calculated in present investigation, was also performed with some standard NLO molecules as well as graphene nanoflakes. Moreover, longitudinal component γ_zzzz of parent compound has been found 12 and 4 times larger than those of previously reported open-shell poly aromatic hydrocarbons (PAH). Interestingly, by increasing the donor ability, i.e., introduction of C₂H₂PhNH₂ groups in place of OC₄H₉ groups (BG compound 3) at terminal positions boosts the <γ> amplitude ∼ 8 times than that of its parent BG compound 1.