同心双涡旋非接触真空吸盘防旋研究

为解决传统单涡旋吸盘由于内部旋转流场的作用引起被吸工件旋转从而导致非接触吸取失效的问题,提出一种同心双涡旋非接触真空吸盘技术方案,其内、外两个涡旋气腔结构同心但气流旋向相反。内涡旋产生真空提供吸力,外涡旋用于平衡内涡旋对工件产生的摩擦转矩。研究该型吸盘工作参数对被吸工件的摩擦转矩及吸力的作用规律,仿真结果表明：同样的供气压力下,外涡旋气流对被吸工件产生的摩擦转矩略大于内涡旋气流,表明可通过适当减小外涡旋腔的供气压力以达到防旋效果;同等供气流量下,双涡旋吸盘的吸力略小于单涡旋吸盘。分析了双涡旋吸盘关键结构参数对吸力的影响规律并进行了正交实验,得到最优结构参数组。加工制作双涡旋吸盘样机并进行了试验研究,结果表明：同等试验条件下,同心双涡旋非接触真空吸盘的吸力与传统的单涡旋吸盘的吸力基本相当,被吸工件所受的摩擦转矩可减小90%左右,很好地抑制了被吸工件的旋转,提高了真空吸取搬运的稳定性和可靠性。     

可控磁路永磁悬浮带式输送机支撑系统研究

针对传统带式输送机托辊轴承产生的旋转阻力等问题,提出一种可控永磁支撑系统。首先,根据有限单元法（FEM）建立单点可控永磁支撑系统模型,通过仿真分析优化影响系统磁场分布的关键结构参数及其对系统悬浮力的影响规律。然后,采用磁路法对系统中导磁体的磁通路径进行区域划分,建立各处磁通路径模型,得出导磁体腿部磁通量解析式,利用等效磁荷法确定永磁贴片表面磁感应强度,结合永磁体间作用力关系,建立单点系统悬浮力模型。其次,利用Maxwell软件确定理论计算模型中修正系数λ1与气隙修正系数ε的数值,并搭建单点支撑系统实验平台,获取系统悬浮力特性关系,验证理论计算模型的准确性。最后,基于单点支撑系统的动力学模型,开展系统PID控制研究。结果表明：系统能较快的稳定于设定值处,为低阻力带式输送机研究提供一定理论基础。     

The utility of coal molecular models

There are a large number (> 125) of molecular representations for coals that span the rank range over seven decades. However, their utility has mostly been in representing chemical structural features, rather than in probing physical structure or exploring the structure-behavior relationship. This paper examines the utility of coal models and reviews the existing and emerging opportunities for coal models to contribute to coals effective utilization via demystification of the structure-behavior relationship. Coal models have been used to explore the coalification pathway, including contraction with water removal. Physical evaluations have probed the density of models as a check on their accuracy. Pore size distribution and sorption have been explored in simple pores and more recent work with carbon dioxide, water and methane sorption within the porous structure of large-scale (< 20,000 atoms) model. Pair distribution frequency and small angle X-ray scattering simulations have also been compared with experimental observations and offer an additional check on the constitution of the model structure. Simulated HRTEM and simulated (calculated) NMR spectra also exist. Models have been disassembled in efforts to represent the pyrolysis process, char formation, and char reactivity (including the role of ion-exchangable ions). Similar to the pyrolysis models, direct liquefaction has been explored with a pyrolysis style approach. Coal-solvent swelling, and coal-solvent solubility have also been explored. While considerable progress has accompanied improvements in computational power and software advances, it is the generation of the model that is the most significant barrier to the meaningful utility of these models. The ability to generate large-scale models (incorporation of molecular weight diversity and structural diversity) with new automation approaches, coupled with new dynamic force-fields that can simulate reactive events in complicated materials like coals, offers a new hope for the utility of coal or char molecular models to probe our understanding and aid in the scientific method rather than our current informed trial and error approach.     

Effects of different force fields and temperatures on the structural character of abeta (12-28) Peptide in aqueous solution

The aim of this work is to investigate the effects of different force fields and temperatures on the structural character of Aβ (12-28) peptide in aqueous solution. Moreover, the structural character of Aβ (12-28) peptide is compared with other amyloid peptides (such as H1 and α-syn12 peptide). The two independent temperature replica exchange molecular dynamics (T-REMD) simulations were completed by using two different models (OPLS-AA/TIP4P and GROMOS 43A1/SPC). We compared the models by analyzing the distributions of backbone dihedral angles, the secondary structure propensity, the free energy surface and the formation of β-hairpin. The results show that the mostly populated conformation state is random coil for both models. The population of β-hairpin is below 8 percent for both models. However, the peptide modeled by GROMOS 43A1 form β-hairpin with turn located at residues F19-E22, while the peptide modeled by OPLS-AA form β-hairpin with turn located at residues L17-F20.     

Electrochemical preparation and characterization of nickel and zinc-modified poly-2-aminothiazole films on mild steel surface and their corrosion inhibition performance

Poly-2-aminothiazole (pAT) was electrochemically synthesized on a mild steel (MS) specimen from 0.3 M aqueous ammonium oxalate solution containing 0.01 M 2-aminothiazole (2-AT) using cyclic voltammetry technique. The synthesized polymer film was then modified by electrodeposition of 100 μg cm⁻² Ni (MS/pAT–Ni) and Zn (MS/pAT–Zn) on top of the polymer surface. The surface morphologies of the polymer films were examined by scanning electron microscopy (SEM) and atomic force microscopy (AFM). The elemental analysis of the surface films was performed by energy dispersive X-ray spectroscopy (EDX). The effectiveness of the coatings in preventing corrosion of MS in 3.5% NaCl solution was assessed using electrochemical techniques. It was found that the obtained coatings were adherent to the steel surface. The pAT film provided a good corrosion protection against the attack of corrosive environment. Moreover, the modification of pAT film by deposition of Ni and Zn on top of the polymer surface significantly enhances the corrosion protection performance of the polymer film by exhibiting an improved barrier effect against the attack of corrosive environment. The surface morphologies and protection ability of the layers were found to be dependent on the type of deposited metal.     

马抗破伤风毒素免疫球蛋白F(ab′)_2新制备工艺的建立

目的建立马抗破伤风毒素免疫球蛋白F(ab′)2新的制备工艺。方法制备并纯化破伤风类毒素(Tetanustoxoid,TT)及重组破伤风毒素c片段(Recombinant tetanus toxin C fragment,rTT-C),将TT/rTT-C(2∶1)免疫马匹,待血清抗体效价达3 500 IU/ml时,采血,分离血清,灭活,去除外源蛋白,胃蛋白酶消化制备F(ab′)2,经DEAE柱层析纯化,并对其进行中和抗体效力、安全性和稳定性检测。结果纯化的TT和rTT-C的浓度分别为70 000 Lf/L和4～5 mg/L,纯度分别达95%以上和96%以上;纯化的TAT-F(ab′)2收率为1.4%,纯度达91%以上,中和抗体效价>15 000 IU/ml;其安全性及稳定性均符合《中国药典》三部(2005版)要求,有效期暂定为18个月。结论建立了马抗破伤风毒素免疫球蛋白F(ab′)2新的制备工艺,制备的制品达到甚至超过了国外的质量标准,为马抗血清同类制品的升级换代提供了技术支持。     

振动力场对销钉螺杆挤出机混炼过程的影响

利用流体动力学软件POLYFLOW对销钉螺杆挤出机的混炼段进行三维等温数值模拟.通过引入振动力场,采用粒子示踪分析方法对比分析不同振动力场参数对销钉螺杆挤出机混炼过程的影响.结果表明,振动力场对销钉的混炼性能有着明显的改善作用,但存在最佳的振动频率和振幅范围.该结论为寻求最优振动力场参数从而提高塑料混炼质量提供了参考.     

Cavity formation and breakup forces in conical spouted beds

A method has been developed to deduce a “breakup” force in a packed bed based on measured pressure drop and internal cavity size hysteresis data in a conical spouted bed. The pressure drop over the vertical jet is estimated by the Eulerian-Eulerian two-fluid model using the commercial Fluent software. The pressure drop over the packed bed is extracted from the measured total pressure drop following a flow rate descending process in the spouted bed, while the “breakup” force is determined from the combination of measured total pressure drop and internal jet height following the flow ascending process, the simulated pressure drop over the gas jet and the pressure drop over the loosely packed upper bed section. Such a proposed method can be applied in the future to develop a generalized expression for the “breakup” force in spouted beds and other packed bed systems where a vertical fluid jet is issued into the packed particles.