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861.
862.
In the nuclear industry, safely managing spent fuels discharged from PWRs (pressurized water reactors) is an ongoing challenge. In this paper, a synergistic coupling of innovative small long‐cycle PWRs and advanced sodium‐cooled fast reactors is considered to reduce the accumulated TRUs (transuranics) by transmuting them with electricity production. In the coupling strategy, the innovative small PWRs employing UO2–ThO2 and fully ceramic micro‐encapsulated fuels are used to deeply burn TRUs from commercial PWRs, while advanced SFRs (sodium‐cooled fast reactors) with actinide recycling are designed to further transmute the TRUs discharged from innovative small PWRs. This work focuses on the core physics analysis of new SFR burner cores using different TRU feeds discharged from small PWRs. Additionally, quasi‐static reactivity balance analyses are performed to understand the safety of the SFR burner cores. The mass flows of TRUs in the nuclear park, which is composed of PWRs, small long‐cycle PWRs, and SFR burners, are analyzed to evaluate TRU inventory reduction. The results of this study show that the advanced SFR burners with all the TRU feed types discharged from the small long‐cycle PWRs have a high TRU consumption rate. They satisfy all of the conditions for self‐controllability under unprotected accidents with a reasonable number of control rods. This coupling strategy requires ~35% less power in conjunction with the advanced SFR burners in the nuclear park and increases the support ratio of SFR burners by ~42% than does the coupling of commercial PWRs and SFR burners. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
863.
864.
为了发挥大型烧结机的效能,进一步降低铁前成本。通过采取稳定烧结用原燃料结构、改进工艺技术、改造设备、推行标准化操作等措施,促进了烧结操作水平的提高,在入烧原料较差的条件下,360m2烧结机固体燃耗大幅度降低。 相似文献
865.
《Ceramics International》2021,47(23):33047-33056
In this paper, two kinds of composites constructed by UO3 nanoflakes (which is UO3·yNH3·xH2O, precisely) and different graphene oxide (GO) nanosheets (homemade GO, GO-h, and commercial GO, GO-c) were prepared via solution chemical reaction. The two kinds of GO share similar morphology and possess the same species of functional groups. Nevertheless, GO-h possesses higher oxidization degree and thus could adsorb more uranyl ions, and the corresponding composite shows a much more regular shape: UO3 nanoflakes and GO nanosheets cross each other, which would help overcome the disadvantage of graphene aggregation. As a result, homemade reduced graphene oxide (RGO-h) sheets inside the final UO2 pellets (named as UO2/GO-h) could construct a well-bulit thermally conductive network to enhance its thermal conductivity. However, similar RGO-c network cannot be observed in the UO2/GO-c pellest originated from GO-c. Therefore, only the thermal conductivity of UO2/GO-h pellet acquires a dramatic increase, 37.30% relative to UO2 pellet at 1200 °C, showing that UO2/GO-h possesses great potential for the development of novel UO2-based ATF fuels. 相似文献
866.
Mikhail G. Akimov Alina M. Gamisonia Polina V. Dudina Natalia M. Gretskaya Anastasia A. Gaydaryova Andrey S. Kuznetsov Galina N. Zinchenko Vladimir V. Bezuglov 《International journal of molecular sciences》2021,22(2)
GPR55 is a GPCR of the non-CB1/CB2 cannabinoid receptor family, which is activated by lysophosphatidylinositol (LPI) and stimulates the proliferation of cancer cells. Anandamide, a bioactive lipid endocannabinoid, acts as a biased agonist of GPR55 and induces cancer cell death, but is unstable and psychoactive. We hypothesized that other endocannabinoids and structurally similar compounds, which are more hydrolytically stable, could also induce cancer cell death via GPR55 activation. We chemically synthesized and tested a set of fatty acid amides and esters for cell death induction via GPR55 activation. The most active compounds appeared to be N-acyl dopamines, especially N-docosahexaenoyl dopamine (DHA-DA). Using a panel of cancer cell lines and a set of receptor and intracellular signal transduction machinery inhibitors together with cell viability, Ca2+, NO, ROS (reactive oxygen species) and gene expression measurement, we showed for the first time that for these compounds, the mechanism of cell death induction differed from that published for anandamide and included neuronal nitric oxide synthase (nNOS) overstimulation with concomitant oxidative stress induction. The combination of DHA-DA with LPI, which normally stimulates cancer proliferation and is increased in cancer setting, had an increased cytotoxicity for the cancer cells indicating a therapeutic potential. 相似文献
867.
Lornella Seeneevassen Emilie Bessde Francis Mgraud Philippe Lehours Pierre Dubus Christine Varon 《International journal of molecular sciences》2021,22(7)
Gastric cancer’s bad incidence, prognosis, cellular and molecular heterogeneity amongst others make this disease a major health issue worldwide. Understanding this affliction is a priority for proper patients’ management and for the development of efficient therapeutical strategies. This review gives an overview of major scientific advances, made during the past 5-years, to improve the comprehension of gastric adenocarcinoma. A focus was made on the different actors of gastric carcinogenesis, including, Helicobacter pylori cancer stem cells, tumour microenvironment and microbiota. New and recent potential biomarkers were assessed as well as emerging therapeutical strategies involving cancer stem cells targeting as well as immunotherapy. Finally, recent experimental models to study this highly complex disease were discussed, highlighting the importance of gastric cancer understanding in the hard-fought struggle against cancer relapse, metastasis and bad prognosis. 相似文献
868.
869.
《International Journal of Hydrogen Energy》2021,46(70):34924-34957
Consumers conventionally adopt diesel generation to meet the energy needs where the grid connection is unreliable or unavailable. While electrification has provided these communities a variety of economic and social opportunities, diesel consumption has resulted in adverse costs and environmental pollution. Two technologies available to reduce the expense and emissions of diesel fuel reliance include dual fuel or hybrid diesel applications. The dual-fuel approach involves a supplementary gas fuel charge in support of reduced diesel fuel consumption. Hybrid applications involve the integration of renewable generation to displace diesel fuel consumption. This paper reviews the potential for hybrid dual-fuel applications, identifying engine flexibility as a major integration barrier. In comparing the flexibility of various dual-fuel technologies to operate dynamically, this paper presents a critical review across hydrogen, liquified petroleum gas (LPG), natural gas (NG) and blended hydrogen and NG derivatives. The results identify a range of approaches able to improve engine flexibility and thus reduce the cost and carbon intensity of diesel-fired internal combustion engines. At low load conditions, while NG and LPG exhibit similar performance, the use of hydrogen and hydrogen blends provide improved engine performance and response. Unfortunately, given the current cost of hydrogen fuel, significant commercial barriers exist to the adoption of hydrogen or hydrogen blended fuels. Despite this, this review indicates the potential of hydrogen-NG blends to offer additional flexibility in comparison to alternative dual-fuel technologies. This position is furthered considering near term cost targets associated with the development of a global green hydrogen industry, coupled with its ability to serve as a demand-side management approach within isolated power systems, one of the multiple future research themes. 相似文献
870.
Md. Jamal Uddin Yeon-Koo Jeong Wontae Lee 《International Journal of Hydrogen Energy》2021,46(20):11458-11481
The study proposes the use of microbial fuel cell (MFC) technology to reduce toxic Cr(VI) present in industrial wastewater to less toxic trivalent chromium [Cr(III)], while generating electricity through a bioelectrochemical oxidation-reduction process. Factors influencing the treatment process and electricity generation include the concentration of Cr(VI) in wastewater, substrate types used for anodes, types of microorganisms involved, types of cathode and anode, surface area of the cathode and anode, and pH and temperature of cathodic and anodic solutions. While other heavy metals in wastewater may be removed by MFC technology, Cr(VI) removal is more efficient in terms of electricity generation. Previous research indicated that the maximum electrical power generated by Cr(VI) removal through the use of MFCs is 1600 mW/m2, which is expected to increase as the factors affecting this process are optimized. Based on current data, MFC-based electricity generation along with Cr(VI) removal is a potential future source of sustainable energy. However, research priorities need to focus on reducing the cost of MFC technology by using economical and effective materials and increasing electricity production. 相似文献