提高16Mn连铸坯控轧合格率

１６Ｍｎ连涛坯进行控轧时，按铸坯碳当量的上限和下限，分别采用两种不同的控轧制度。在邯钢中板分厂试轧的结果，轧材合格率均达到９６％以上，投产后轧材合格率达到９８％以上。     

Efficient and optimal exponentiation in finite fields

Optimal sequential and parallel algorithms for exponentiation in a finite field containing F _q are presented, assuming thatqth powers can be computed for free.     

16MnR钢板超声波检测不合原因分析

为找出16MnR钢板超声波检测不合的原因,在检测缺陷部位取样,借助电子显微镜和电子探针,对钢板组织和微区成分进行了分析。结果表明,检测不合的主要原因是组织中存在的氧化物、硫化物夹杂,C、Mn等元素的成分偏析以及由夹杂物造成的疏松和微裂纹。采取提高钢质纯净度、控制浇注温度和拉速等改进措施,检测合格率由82.5%提高到92%。     

UniMAT PLC在塑料挤出机控制系统中的应用

针对塑料挤出机控制系统成本高、速度低、精度低的问题,提出采用UniMATPLC控制方式,实践证明效果良好。     

P16 and HPV Genotype Significance in HPV-Associated Cervical Cancer—A Large Cohort of Two Tertiary Referral Centers

The expression of p16 is a good surrogate of human papillomavirus (HPV) infection in HPV-associated cancers. The significance of p16 expression, HPV genotype and genera in the outcome of patients with HPV-associated cervical cancer (CC) is unclear. Our aim is to ascertain the prognostic significance of these factors. Data from 348 patients (median age: 47.5 years old) with CC, diagnosed in two referral centers, were retrospectively collected. Advanced disease (FIGO2018 IB2-IV) was present in 68% of patients. A single HPV genotype was identified in 82.8% of patients. The most common HPVs were HPV16 (69%) and HPV18 (14%). HPV genera reflected this distribution. HPV16 tumors presented at an earlier stage. P16 was negative in 18 cases (5.2%), 83.3% of which were squamous cell carcinomas. These cases occurred in older patients who tended to have advanced disease. In the univariate analysis, HPV16 (HR: 0.58; p = 0.0198), α-9 genera (HR: 0.37; p = 0.0106) and p16 overexpression (HR: 0.54; p = 0.032) were associated with better survival. HPV16 (HR: 0.63; p = 0.0174) and α-9 genera (HR: 0.57; p = 0.0286) were associated with less relapse. In the multivariate analysis, only the International Federation of Gynecology and Obstetrics (FIGO) stage retained an independent prognostic value. HPV16, α-9 genera and p16 overexpression were associated with better survival, although not as independent prognostic factors. Patients with p16-negative HPV-associated CC were older, presented with advanced disease and had worse prognosis.     

In Vitro Characterization of Neutralizing Hen Antibodies to Coxsackievirus A16

Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease (HFMD). Children aged <5 years are the most affected by CA16 HFMD globally. Although clinical symptoms of CA16 infections are usually mild, severe complications, such as aseptic meningitis or even death, have been recorded. Currently, no vaccine or antiviral therapy for CA16 infection exists. Single-chain variable fragment (scFv) antibodies significantly inhibit viral infection and could be a potential treatment for controlling the infection. In this study, scFv phage display libraries were constructed from splenocytes of a laying hen immunized with CA16-infected lysate. The pComb3X vector containing the scFv genes was introduced into ER2738 Escherichia coli and rescued by helper phages to express scFv molecules. After screening with five cycles of bio-panning, an effective scFv antibody showing favorable binding activity to proteins in CA16-infected lysate on ELISA plates was selected. Importantly, the selected scFv clone showed a neutralizing capability against the CA16 virus and cross-reacted with viral proteins in EV71-infected lysate. Intriguingly, polyclonal IgY antibody not only showed binding specificity against proteins in CA16-infected lysate but also showed significant neutralization activities. Nevertheless, IgY-binding protein did not cross-react with proteins in EV71-infected lysate. These results suggest that the IgY- and scFv-binding protein antibodies provide protection against CA16 viral infection in in vitro assays and may be potential candidates for treating CA16 infection in vulnerable young children.     

Dynamics of Bacterial Community Structure in the Rhizosphere and Root Nodule of Soybean: Impacts of Growth Stages and Varieties

Bacterial communities in rhizosphere and root nodules have significant contributions to the growth and productivity of the soybean (Glycine max (L.) Merr.). In this report, we analyzed the physiological properties and dynamics of bacterial community structure in rhizosphere and root nodules at different growth stages using BioLog EcoPlate and high-throughput sequencing technology, respectively. The BioLog assay found that the metabolic capability of rhizosphere is in increasing trend in the growth of soybeans as compared to the bulk soil. As a result of the Illumina sequencing analysis, the microbial community structure of rhizosphere and root nodules was found to be influenced by the variety and growth stage of the soybean. At the phylum level, Actinobacteria were the most abundant in rhizosphere at all growth stages, followed by Alphaproteobacteria and Acidobacteria, and the phylum Bacteroidetes showed the greatest change. But, in the root nodules Alphaproteobacteria were dominant. The results of the OTU analysis exhibited the dominance of Bradyrhizobium during the entire stage of growth, but the ratio of non-rhizobial bacteria showed an increasing trend as the soybean growth progressed. These findings revealed that bacterial community in the rhizosphere and root nodules changed according to both the variety and growth stages of soybean in the field.     

Johnson-Cook dynamic constitutive relationship for TC 16 titanium alloy

The true stress--strain curves of TC16 alloy with a wide range of strain rates were investigated under uniaxial quasi-static tension and uniaxial dynamic compression with the lnstron 8032 test machine and the split Hopkinson bar respectively. The results indicate that the true stress increases with increasing strain rate, while decreases with increasing temperature. Under the 105 s^-1 high strain rate and temperature higher than 673 K, the true stress would even be less than that under quasi-static condition. A new method incorporating TCl6＇s stress strain curve developing item was proposed to determine the coefficients in J-C model easily and to avoid the estimation of the adiabatic temperature rising. The Johnson-Cook dynamic constitutive relationship for TC16 was obtained for the first time. Good agreement was obtained between the model prediction and the experimental stress--strain curves for TC16 under both quasi-static and dynamic loadings.     

16MnR 容器板性能不合格的原因

运用扫描电镜、金相检验和力学检验对不合格的16MnR容器板进行了检验分析。结果表明，材料中的条状MnS夹杂物和少量的马氏体、贝氏体组织是导致钢板延伸、冲击性能不合格的主要原因。     

Monel400与16MnR异种金属的焊接

通过对Mone1400与16MnR的性能分析和试验。确定了焊接方法和焊接工艺参数。获得了优质的焊接接头，解决了Mone1400与16MnR异种金属焊接的技术难题，并成功地应用于化工设备的制造。