Protein interaction networks: centrality,modularity, dynamics,and applications

In the post-genomic era, proteomics has achieved significant theoretical and practical advances with the development of high-throughput technologies. Especially the rapid accumulation of protein-protein interactions (PPIs) provides a foundation for constructing protein interaction networks (PINs), which can furnish a new perspective for understanding cellular organizations, processes, and functions at network level. In this paper, we present a comprehensive survey on three main characteristics of PINs: centrality, modularity, and dynamics. 1) Different centrality measures, which are used to calculate the importance of proteins, are summarized based on the structural characteristics of PINs or on the basis of its integrated biological information; 2) Different modularity definitions and various clustering algorithms for predicting protein complexes or identifying functional modules are introduced; 3) The dynamics of proteins, PPIs and sub-networks are discussed, respectively. Finally, the main applications of PINs in the complex diseases are reviewed, and the challenges and future research directions are also discussed.     

复杂系统平均寿命的估计和性质

根据已知的基于最小路径或最小割集复杂系统可靠度函数的解析表达式,给出当子系统寿命分布服从指数分布时,系统平均寿命的表达式.利用这一表达形式,在子系统寿命变量服从指数分布条件下,分别就完全数据和截尾数据两种情况,给出了系统平均寿命的估计,并对估计性质进行了研究.并在完全数据下,给出了估计的渐近分布.     

利用金属络合物的电火花加工研究

在电火花加工的工作液中添加络合剂，使之与被蚀除的金属颗粒产生络合化学反应，生成可溶于工作液中的络合物。利用这种原理，可提高电火花加工性能，在小孔、深槽等加工应用中起到促进排屑的作用。     

Synchronization for linear singularly perturbed complex networks with coupling delays

This paper is concerned with the synchronization problem about linear singularly perturbed complex network system with coupling delay. The sufficient delay-dependent conditions for the synchronization of the network are established by introducing an equivalent network system with the Lyapunov stability theory. These conditions, which are formulated in terms of linear matrix inequalities, can be solved efficiently by the LMI toolbox of MATLAB. A simulation example is provided to show the validity of the proposed the synchronization conditions of the whole network.     

基于聚类和动态LOD的三维地形建模方法

为提高基于DEM高程数据的三维大地形绘制效率,提出基于K-means聚类和动态LOD的三维地形建模方法。对高程数据集使用K-means聚类分析方法,发现地形数据的自相似性,建立数据采样点与地貌特征分类的自动关联;依据采样点的地貌属性值完成粗化处理,构建不规则三角网模型;采用局部优化算法进行有限域内的三角形分裂以实现三角网的动态更新,结合克里金插值法实现插入点的精确计算,形成LOD层次细节多分辨率模型。实验结果表明,该方法对不同类型地形都获得了较高的数据简化率,提高了三维模型的绘制效率,具有较好的地形特征保持性。     

制造物联网中高吞吐率复杂事件检测技术研究

复杂事件处理能非常有效地检测到事件流中有价值的模式,高吞吐率意味着单位时间内获取更多有价值的信息.为复杂事件处理提出一种提高吞吐率的查询技术,通过聚集活动实例栈中的连接,并批量执行序列构造,减少了相同连接的遍历,降低了序列构造处理的运行频率,从而提高了复杂事件处理的吞吐率.仿真实验表明:提出的方案相比于SASE提出的传统方案,吞吐率有数倍的提升.     

复形态双向联想记忆网络及其性能分析

基于复数环(C,∨,∧,+)提出了复形态双向联想记忆网络模型,给出了神经网络实现双向完全联想记忆的条件,并分析了自联想的存储能力、稳定性和收敛性及神经网络的抗噪声能力.当复数虚部取零时即为实数,实数域形态双向联想记忆网络就是复数域形态双向联想记忆网络的特例.最后通过仿真实验验证复形态双向联想记忆网络的有效性.     

MotionView及HyperStudy在全地形车前悬架设计中的应用

为解决全地形车大行程前悬架的悬架跳动与前束角变化的协调问题,研究一款全地形车前悬架的运动学模型.在MotionView中建立该全地形车前悬架的运动学模型,借助HyperStudy对悬架跳动与前束角变化关系曲线进行优化,获得与理想曲线较接近的结果.     

Toward a Conceptual Emulation Framework for the Preservation of Archaeological 3D Visualizations

Through the Preservation of Complex Objects Symposia (POCOS), leading researchers and practitioners have managed to propose strategies for preserving digital art and computer games. The same is not true for the preservation of archaeological visualizations. This article therefore discusses the following question: “Can emulation be employed to effectively preserve obsolete computer visualizations from the Archaeology domain?” Guidelines and test results coming from this work would be of great benefit to the archaeological community, and would contribute knowledge to other research communities, specifically those interested in similar data types/3D visualizations.     

噪声信道下输出耦合复杂动态网络的状态估计

文中研究了一类带有噪声的复杂动态网络的状态估计问题,不同于现有的根据节点的状态变量构造观测器的方法,文中利用节点的输出变量构造观测器,并基于积分控制的思想提出了一种估计网络状态的新方案。根据李雅普诺夫稳定性判据,所提出的构思的可行性得到了论证,并且以线性矩阵不等式的形式给出了状态估计的充分条件。分别以无标度网络和小世界网络为模型,以Lorenz混沌映射作为复杂网络的节点进行数值化仿真。研究表明,这种方法能够使系统状态的估计误差收敛于0,仿真的结果进一步证明了文中所提方案的有效性。