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41.
针对国内漂浮式风电全生命周期成本研究尚不足的问题,提出一种评估漂浮式海上风电机组全生命周期成本细分的方法。该方法将漂浮式海上风电机组全生命周期划分为前期调研、设计、制造、安装、运行维护和拆解等6个阶段,涉及每个阶段的阶段成本,并将各阶段成本细分为不同的子成本,得到全生命周期多层次成本构成,并据此分析获得影响全生命周期总成本的关键变量。以某半潜式浮式风机为例,分析其全生命周期每个阶段的成本构成,从而获得最重要的成本,并将其最小化以提高浮式风机经济效应。研究结果表明,控制制造成本和安装成本是提高浮式风机经济性的关键。 相似文献
42.
GENG Jun-bao JIN Jia-shan ZHANG Jun College of Naval Architecture Power Naval University of Engineering Wuhan P.R. China 《国际设备工程与管理》2010,(1)
Reliability, maintainability, supportability (RMS) are the important performance indexes of equipment, which affect not only the availability, but also the life cycle cost (LCC) of the equipment. First discussed is the qualitative relation between reliability and LCC and the costs which may be used to enhance the reliability. Secondly, the factors that affect the maintainability are summarized, and if maintainability is advanced, the trend of the LCC is depicted. Thirdly, the qualitative relation between th... 相似文献
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Philipp Kasper Jaco Selle Christina Vohlen Rebecca Wilke Celien Kuiper-Makris Oleksiy Klymenko Inga Bae-Gartz Charlotte Schmig Alexander Quaas Bjrn Schumacher Münevver Demir Martin Bürger Sonja Lang Anna Martin Hans-Michael Steffen Tobias Goeser Jrg Dtsch Miguel A. Alejandre Alcazar 《International journal of molecular sciences》2022,23(10)
Maternal obesity predisposes for hepato-metabolic disorders early in life. However, the underlying mechanisms causing early onset dysfunction of the liver and metabolism remain elusive. Since obesity is associated with subacute chronic inflammation and accelerated aging, we test the hypothesis whether maternal obesity induces aging processes in the developing liver and determines thereby hepatic growth. To this end, maternal obesity was induced with high-fat diet (HFD) in C57BL/6N mice and male offspring were studied at the end of the lactation [postnatal day 21 (P21)]. Maternal obesity induced an obese body composition with metabolic inflammation and a marked hepatic growth restriction in the male offspring at P21. Proteomic and molecular analyses revealed three interrelated mechanisms that might account for the impaired hepatic growth pattern, indicating prematurely induced aging processes: (1) Increased DNA damage response (γH2AX), (2) significant upregulation of hepatocellular senescence markers (Cdnk1a, Cdkn2a); and (3) inhibition of hepatic insulin/insulin-like growth factor (IGF)-1-AKT-p38-FoxO1 signaling with an insufficient proliferative growth response. In conclusion, our murine data demonstrate that perinatal obesity induces an obese body composition in male offspring with hepatic growth restriction through a possible premature hepatic aging that is indicated by a pathologic sequence of inflammation, DNA damage, senescence, and signs of a possibly insufficient regenerative capacity. 相似文献
45.
LCA数据清单分析研究 总被引:6,自引:4,他引:6
在分析生命周期评价的技术框架基础上,探讨了LCA中数据收集及编制数据清单分析中若干问题。 相似文献
46.
With the development of MEMS and the electronic devices's miniaturization and integration, a new kind of power sources that can satisfy the need for high energy density is required. Microbatteries are being researched abroad for their advantages of extreme thinness and long-term power supply. The development of MEMS microbatteries are reviewed and suggestedmagnetron sputtering in fabricating a high-performance microbattery. The technics as annealing are analyzed. The microbattery with a LiNi1-x Cox O2 cathode exhibited stable cycle ability and a high specific discharge capacity, which was attributed to the alloying effect of the LiNiO2and LiCoO2. 相似文献
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根据等效焓降法在热力系统计算时的特点,推导了循环函数法在回热系统中的局部定量计算方法,导出了回热系统局部定量计算的几个重要结论.最后,通过实例计算对所得结论进行了验证.验证结果表明,该方法在回热系统局部定量计算过程中具有简洁、准确、概念清晰等特点,适合推广. 相似文献
50.
Giacomo Lazzarino Valentina Di Pietro Marco Rinaudo Zsuzsanna Nagy Nicholas M. Barnes Lars Bruce Stefano Signoretti Renata Mangione Miriam Wissam Saab Barbara Tavazzi Antonio Belli Giuseppe Lazzarino Angela Maria Amorini Ann Logan 《International journal of molecular sciences》2022,23(15)
In a previous study, we found that administration of ILB®, a new low molecular weight dextran sulphate, significantly improved mitochondrial functions and energy metabolism, as well as decreased oxidative/nitrosative stress, of brain tissue of rats exposed to severe traumatic brain injury (sTBI), induced by the closed-head weight-drop model of diffused TBI. Using aliquots of deproteinized brain tissue of the same animals of this former study, we here determined the concentrations of 24 amino acids of control rats, untreated sTBI rats (sacrificed at 2 and 7 days post-injury) and sTBI rats receiving a subcutaneous ILB® administration (at the dose levels of 1, 5 and 15 mg/kg b.w.) 30 min post-impact (sacrificed at 2 and 7 days post-injury). Additionally, in a different set of experiments, new groups of control rats, untreated sTBI rats and ILB®-treated rats (administered 30 min after sTBI at the dose levels of 1 or 5 mg/kg b.w.) were studied for their neurocognitive functions (anxiety, locomotor capacities, short- and long-term memory) at 7 days after the induction of sTBI. Compared to untreated sTBI animals, ILB® significantly decreased whole brain glutamate (normalizing the glutamate/glutamine ratio), glycine, serine and γ-aminobutyric acid. Furthermore, ILB® administration restored arginine metabolism (preventing nitrosative stress), levels of amino acids involved in methylation reactions (methionine, L-cystathionine, S-adenosylhomocysteine), and N-acetylaspartate homeostasis. The macroscopic evidences of the beneficial effects on brain metabolism induced by ILB® were the relevant improvement in neurocognitive functions of the group of animals treated with ILB® 5 mg/kg b.w., compared to the marked cognitive decline measured in untreated sTBI animals. These results demonstrate that ILB® administration 30 min after sTBI prevents glutamate excitotoxicity and normalizes levels of amino acids involved in crucial brain metabolic functions. The ameliorations of amino acid metabolism, mitochondrial functions and energy metabolism in ILB®-treated rats exposed to sTBI produced significant improvement in neurocognitive functions, reinforcing the concept that ILB® is a new effective therapeutic tool for the treatment of sTBI, worth being tested in the clinical setting. 相似文献