基于MQTT的智能宠物追踪系统

针对当前宠物频繁丢失的问题,本文设计并实现了基于MQTT协议的智能宠物追踪系统.系统的功能实现主要依托于MQTT服务器、Web服务器和基于Android平台开发的应用程序.嵌入式设备采用集成MTK2503芯片组的WZ-203CS开发板,依靠开发板内嵌的物联网卡,通过MQTT消息传输协议,将位置信息传送至Android应用程序.应用程序通过集成高德地图导航功能,利用已接收的位置信息,提供语音导航、路径规划等功能.基于该架构设计的追踪系统,并不局限于宠物追踪,通过系统预留的接口可扩展其他相关功能,实现可用性的同时具有较强的可扩展性.     

云联智慧电梯控制系统设计

随着社会经济的不断发展,高层建筑也在不断增加,电梯成为人们日常出行的一个重要运载工具。然而电梯的大规模使用,电梯安全问题也逐渐成为人们关注的焦点,有关电梯困人、电梯门异常打开导致乘客坠亡的新闻时有报道,引发了人们对电梯安全问题的深入思考[1]。为确保电梯运行安全,国家有关部门会对使用中的电梯进行必要的安全检测。但目前国内的电梯安全检测主要还是以人工检测为主,依据经验对电梯的安全状态进行判断,效率低下且结果容易受人为因素影响,因此获取电梯传感器信息和电梯监控视频进行远程自动化诊断就显得尤为重要[2]。     

基于视频发送端速率控制的QoS技术研究

基于尽力而为的网络模式不能提供QoS保证,网络拥塞和分组丢失不可避免。在端到端视频单播结构下,论文提出了一个发送端速率控制框架SRCF,在此框架下首先利用RTCP报文中的字段提出了一种网络参数测量方法,然后设计了一个自适应速率算法SRCA,SRCA利用已得到的网络传输延迟和分组丢失率参数作为初始参数,来调整编码速率,达到充分利用带宽的目的,避免了视频质量由于调整参数带来的剧烈抖动。仿真结果表明,该算法在网络出现一定拥塞的条件下,能跟踪带宽的变化,网络和媒体QoS能保证视频质量较好。     

ABS树脂的无卤膨胀阻燃研究

以聚酰胺6(PA6)为协效成炭剂,将膨胀型阻燃剂聚磷酸铵(APP)应用于ABS树脂,通过氧指数(OI)测定及UL94测定,探讨了PA6、APP含量对阻燃体系阻燃性能的影响;同时,对复合体系进行了热失重分析,并采用扫描电镜(SEM)观察了复合物燃烧后炭层结构。结果表明:PA6的加入明显提升了体系成炭率,降低了最大热失重速率,ABS/PA6/APP体系燃烧表面形成了膨胀、均匀、致密的炭层结构。当PA6/ABS=20/80时,阻燃性能最佳,当APP含量为25%时,OI可以达到30%,UL94测定达V—1级;当APP含量为35%时,UL94测定达V—0级。     

APP对木粉-HDPE复合材料阻燃和力学性能的影响

以聚磷酸铵(APP)对木粉-HDPE复合材料(WF-HDPE)进行阻燃处理,用锥形量热仪系统评价复合材料的阻燃性能,并进行等温燃烧反应动力学分析,用万能力学试验机进行静态力学试验。结果表明,在35 kW/m2热辐射流量下,APP添加量达到15%时,WF-HDPE燃烧热释放速率(RHR)峰值和总热释放量(THR)均降低约50%、成炭率提高150%,表现出显著的阻燃作用;可用动力学模型ln(1-α)=-kt+C描述WF-HDPE的等温燃烧反应,APP的加入使反应速率常数k降低、半衰期延长。APP对WF-HDPE的冲击性能有显著的不利影响,但能改善刚性,对弯曲强度和拉伸强度影响不大。综合阻燃性能与力学实验结果,APP的适宜添加量为15%左右。     

基于多Agent技术的分布式电压无功优化控制系统

全网电压无功控制是一个复杂的、分布式的优化控制问题,为了更好地解决这个问题,文章提出了基于多Agent技术的分布式电压无功优化控制系统,该系统符合电压无功控制装置分散配置的特点,Agent之间相互协调,根据辅助问题原理进行全网并行无功优化计算,数据通信量少,收敛速度快.Agent根据优化计算结果自动调整电压无功模糊判据的控制范围,进行电压无功实时控制,自学习能力强.该系统功能强大,具有较高的适应性、灵活性、智能性和可扩展性.     

聚合物改性沥青微观结构与性能关系的研究

本文用扫描电子显微镜（ＳＥＭ）研究了ＡＰＰ与ＳＢＳ改性沥青的微观形态结构．测定了这两种改性沥青的物理性能（软化点，延伸度）随改性材料用量的变化规律，着重讨论了形态结构与这些性能变化之间的关系。研究结果表明：ＡＰＰ改性沥青形成了均相结构，ＳＢＳ改性沥青形成了非均相结构，ＡＰＰ和ＳＢＳ对沥青物理性能的改善与改性沥青的微观结构密切相关。     

Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model,and the Effects of P33, a Putative Neuroprotective Agent Thereon

Neurogenesis plays a crucial role in cognitive processes. During aging and in Alzheimer’s disease (AD), altered neurogenesis and neuroinflammation are evident both in C57BL/6J, APP_Swe/PS1_dE9 (Tg) mice and humans. AD pathology may slow down upon drug treatment, for example, in a previous study of our group P33, a putative neuroprotective agent was found to exert advantageous effects on the elevated levels of APP, Aβ, and neuroinflammation. In the present study, we aimed to examine longitudinal alterations in neurogenesis, neuroinflammation and AD pathology in a transgenic (Tg) mouse model, and assessed the putative beneficial effects of long-term P33 treatment on AD-specific neurological alterations. Hippocampal cell proliferation and differentiation were significantly reduced between 8 and 12 months of age. Regarding neuroinflammation, significantly elevated astrogliosis and microglial activation were observed in 6- to 7-month-old Tg animals. The amounts of the molecules involved in the amyloidogenic pathway were altered from 4 months of age in Tg animals. P33-treatment led to significantly increased neurogenesis in 9-month-old animals. Our data support the hypothesis that altered neurogenesis may be a consequence of AD pathology. Based on our findings in the transgenic animal model, early pharmacological treatment before the manifestation of AD symptoms might ameliorate neurological decline.     

SPIN90 Deficiency Ameliorates Amyloid β Accumulation by Regulating APP Trafficking in AD Model Mice

Alzheimer’s disease (AD), a common form of dementia, is caused in part by the aggregation and accumulation in the brain of amyloid β (Aβ), a product of the proteolytic cleavage of amyloid precursor protein (APP) in endosomes. Trafficking of APP, such as surface-intracellular recycling, is an early critical step required for Aβ generation. Less is known, however, about the molecular mechanism regulating APP trafficking. This study investigated the mechanism by which SPIN90, along with Rab11, modulates APP trafficking, Aβ motility and accumulation, and synaptic functionality. Brain Aβ deposition was lower in the progeny of 5xFAD-SPIN90KO mice than in 5xFAD-SPIN90WT mice. Analysis of APP distribution and trafficking showed that the surface fraction of APP was locally distinct in axons and dendrites, with these distributions differing significantly in 5xFAD-SPIN90WT and 5xFAD-SPIN90KO mice, and that neural activity-driven APP trafficking to the surface and intracellular recycling were more actively mobilized in 5xFAD-SPIN90KO neurons. In addition, SPIN90 was found to be cotrafficked with APP via axons, with ablation of SPIN90 reducing the intracellular accumulation of APP in axons. Finally, synaptic transmission was restored over time in 5xFAD-SPIN90KO but not in 5xFAD-SPIN90WT neurons, suggesting SPIN90 is implicated in Aβ production through the regulation of APP trafficking.     

中国互联网细分领域评价研究

基于相关企业自主报送的数据和第三方专业机构的数据,科学选取指标体系和评价方法,对国内主流视频网站、软件应用商店、电子商务网站和搜索引擎服务的发展情况进行综合评价。以帮助公众了解互联网应用发展情况,鼓励和推动互联网创新,进一步刺激互联网信息消费需求,促进互联网行业和互联网信息消费健康、持续发展。