Repeatedly foldable AMOLED display

In this study, a 5.9‐inch foldable active‐matrix organic light emitting diode (AMOLED) display was developed. A folding test was performed repeatedly. The display survived the folding test (100,000 folds) with a curvature radius of 2 mm. To protect an organic light emitting diode (OLED) against moisture, inorganic passivation layers are provided on the upper and lower sides of the flexible display. Using our transfer technology, high density passivation layers can be obtained. The measured water vapor transmission rate of the layer is 7 × 10^?6 g/m²?day or less, which improves OLED reliability. With these techniques, we have developed a book‐type display, which is repeatedly foldable like a book, and a tri‐fold display including a display area, which is foldable in three.     

基于并行群体模拟退火算法的蛋白质折叠研究

蛋白质折叠研究对于揭示蛋白结构和功能关系,进而了解相关疾病的致病机理意义重大。蛋白质折叠已被证明是 NP-完全问题。本文针对蛋白质折叠研究中的能量最小化问题,提出了一种新的并行群体模拟退火算法（Parallel Group Simulated Annealing,PGSA）及其改进型算法（PGSA_1/K)。该算法使用了降温因子加速收敛精度,并采用 MPI 消息传递并行编程技术加快蛋白质结构空间搜索以及能量最小化寻找速度。以 Met_Enkephalin 蛋白为对象的计算机模拟仿真结果表明,我们提出的算法及其改进型有很好的扩展性,可以高效搜索蛋白结构空间,从而找到相关蛋白的最小能量结构。     

以太网中双绞线超长布线的论证和实践

在IEEE802．3系列标准以太网的布线中,五类双绞线的长度限制在100米内,当距离超长时,会造成网络故障。为了解决这个问题,本文主要分析CSMA／CD和双绞线的性能,对超出传输长度的限制进行分析。最后还通过实测证明在一定环境距离内,超长使用廉价双绞线替代高成本光缆设备的可行性。     

弱信号锁相放大CD552-R3电路

锁相放大电路是微弱信号检测的重要方法.基于CD552-R3相敏检波芯片设计了一种锁相放大电路,应用于大背景噪声下微弱信号的检测.采用信号发生器产生的标准信号和染噪信号,对该锁相放大电路进行了鉴幅和鉴相性能测试,并在不同强度噪声下对弱信号进行检测.测试结果表明:研制的锁相放大电路输出线性度高于0.9999,具有良好的鉴幅和鉴相特性,能将信噪比为-36 dB的毫伏级信号提取出来,可用于大背景噪声下微弱信号的检测.     

基于OPNET的CSMA/CD改进与仿真

以太网中采用CSMA/CD使得网络时延不确定和时变与时延的随机性导致控制品质的下降,为了改善以太网的延迟抖动性能,对以太网采用的TBEB算法进行改进,提出自适应退避算法,并用OPNET对改进的算法进行仿真分析.     

基于DEVS/CD++的抢险救灾物资保障仿真建模研究

突发自然灾害条件下的抢险救灾行动是典型的离散事件系统,在分析离散事件系统规范(DEVS)模型描述的基础上,构建了抢险救灾物资保障DEVS仿真模型,分析了仿真实体,设计了仿真流程,给出了耦合模型和主要原子模型结构。并在CD++中对该模型进行了仿真试验,得到了较为合理的仿真结果,为开展抢险救灾应急保障模拟训练奠定了基础。     

基于Toy模型蛋白质折叠预测的多种群微粒群优化算法研究

基于Toy模型的蛋白质折叠结构预测问题是一个典型的NP问题.提出了多种群微粒群优化算法用于计算蛋白质能量最小值.该算法采用了一种新的算法结构,在该结构中,每一代的种群被分为精英子种群、开采子种群和勘探子种群三部分,通过改善种群的局部开采能力和全局勘探能力来提高算法的性能.分别采用Fibonacci蛋白质测试序列和真实蛋白质序列进行了折叠结构预测的仿真实验.实验结果表明该算法能够更精确地进行蛋白质折叠结构预测,为生物科学研究提供了一条有效途径.     

Impact of asphalt concrete fatigue endurance limit definition on pavement performance prediction

Many well-constructed Hot Mix Asphalt pavements have been in service for 40 or more years without any evidence of fatigue cracking. This field experience suggests that there exists a strain level, known as the fatigue endurance limit (FEL), below which an asphalt concrete pavement will not exhibit fatigue cracks. Several studies have been conducted to define and verify this limit. Each of these methods is associated with certain assumptions regarding the nature of the FEL and heretofore a comprehensive comparison of each has not been made using a consistent set of mixtures. Likewise, the impact of any observed differences in FEL on the predicted pavement performance has not been made. This paper investigates and compares six different methods for identifying the FEL: NCHRP 9–44A approach, simplified viscoelastic continuum damage model, smeared-healing with continuum damage model, plateau value approach, pseudo-strain analysis method, and reduced cycles method. Each method is found to yield different values ranges from approximately 30–170 microstrains at 21.1 °C. The predicted FEL from each of the six methods are then used with the mechanistic empirical design algorithm to evaluate their effects on predicted pavement performance. Simulation outputs show different pavement performance and perpetual pavement structural design thicknesses from each of the methods. The study outcomes are expected to benefit future field verification research of FEL as it provides comprehensive analyses using six different methods. This future verification research may indicate the method that best represents actual perpetual pavement design and performance.     

Drug self-assembly: A phenomenon at the nanometer scale with major impact in the structure–biological properties relationship and the treatment of disease

Under water-rich conditions, small amphiphilic and hydrophobic drug molecules self-assemble into supramolecular nanostructures. Thus, substantial modifications in their interaction with cellular structures and the ability to reach intracellular targets could happen. Additionally, drug aggregates could be more toxic than the non-aggregated counterparts, or vice versa. Moreover, since self-aggregation reduces the number of effective “monomeric” molecules that interact with the target, the drug potency could be underestimated. In other cases, the activity could be ascribed to the non-aggregated molecule while it stems from its aggregates. Thus, drug self-assembly could mislead from drug throughput screening assays to advanced preclinical and clinical trials. Finally, aggregates could serve as crystallization nuclei. The impact that this phenomenon has on the biological performance of active compounds, the inconsistent and often controversial nature of the published data and the need for recommendations/guidelines as preamble of more harmonized research protocols to characterize drug self-aggregation were main motivations for this review. First, the key molecular and environmental parameters governing drug self-aggregation, the main drug families for which this phenomenon and the methods used for its characterization are described. Then, promising nanotechnology platforms investigated to prevent/control it towards a more efficient drug development process are briefly discussed.     

非线性规划在工业产品设计中的应用

目的判断非线性规划方法能否在满足用户使用要求的前提下节约生产加工成本。方法以平板折叠桌作为研究对象,以加工方便作为目标函数,以桌面和桌腿之间的几何关系作为约束条件,建立非线性规划模型,通过MATLAB软件求解得到最优加工方案。结论在给定高为70 cm和圆形桌面直径为80 cm时,平板折叠桌最优加工方案为平板长度158 cm,宽度79.9 cm,厚度3 cm,木条宽度4.7 cm,单侧木条数为17条。