自动控制折页机的折页单元优化组配方法研究

对折页单元结构、折痕的形成以及折页机的类型进行了分析,根据折痕的相对位置与变向性分析研究了折页模式的分解,将复杂折页模式分解为一系列平行折的顺次组合;分析了折页模式与折页路径的映射关系,给出了提高前端折页单元利用率的路径选取原则;在此基础上结合折页单元的组配规则提出一种优化折页机配置的折页单元组配方法,并以一个示例阐述了折页单元优化组配方法的实施步骤与过程.     

蛋白质体外折叠技术研究现状与展望

蛋白质折叠技术是生物工程的新“单元操作”。本文阐述了蛋白质体外折叠研究的重要理论意义和应用价值，综述了目前蛋白质体外折叠技术研究进展，最后对蛋白质折叠技术的研究进行了展望。     

Effect of secondary structure on the conformations and folding behaviors of protein-like chains

We present a new model considering the effects of secondary structure on the conformations and folding process of protein-like chains in three-dimensional simple cubic lattice in this paper. The properties such as chain dimensions, shape, average contacts and chain average energy with different helical energy of a helix (ε_hel=0, −0.75, −1.5, and −3 in the unit of kT) are discussed here. Unlike conventional polymers, protein-like chains are much compact. We also find that the ability to form helix of residue is different under the condition of different helical energy of a helix. The energy distribution for protein-like chains with different length and the conformation changes in the process of folding of proteins are discussed. Comparisons with real protein chains are also made.     

Parameter optimization for the Gaussian model of protein folding

Computational models of protein folding and ligand docking are large and complex. Few systematic methods have yet been developed to optimize the parameters in such models. We describe here an iterative parameter optimization strategy that is based on minimizing a structural error measure by descent in parameter space. At the start, we know the ‘correct’ native structure that we want the model to produce, and an initial set of parameters representing the relative strengths of interactions between the amino acids. The parameters are changed systematically until the model native structure converges as closely as possible to the correct native structure. As a test, we apply this parameter optimization method to the recently developed Gaussian model of protein folding: each amino acid is represented as a bead and all bonds, covalent and noncovalent, are represented by Hooke's law springs. We show that even though the Gaussian model has continuous degrees of freedom, parameters can be chosen to cause its ground state to be identical to that of Go-type lattice models, for which the global ground states are known. Parameters for a more realistic protein model can also be obtained to produce structures close to the real native structures in the protein database.     

Nonlocalized fatigue damage of metals and alloys. Part 3. Strain and energy criteria

The paper considers methods of accelerated determination of endurance limits of metals and alloys based on the analysis of regularities in their inelastic deformation, strain and energy criteria of fatigue fracture, and methods for life prediction with the use of those criteria. __________ Translated from Problemy Prochnosti, No. 1, pp. 5–31, January–February, 2006.     

GPS中新的P码直接捕获算法的提出与分析

目前P码的捕获通常是利用C/A码来完成.为保证扩频信号具有更高的扩频增益、更强的抗模仿和抗欺骗能力,必须实现P码的直接捕获,而不依赖于其他短码来捕获.本文从研究信号直接捕获算法角度出发,提出了一种新的P码快速直接捕获算法.仿真结果表明:该算法能够达到有效的P码捕获.     

便携式瓦斯报警仪充电控制电路的研究与设计

针对目前便携式瓦斯报警仪在使用中存在放电时间短的问题,从软件上提出了一种针对镍氢电池充电的新方法。该方法提高了检测镍氢电池充电曲线下降沿的可靠性,延长了便携式瓦斯报警仪的单次放电时间。     

电磁式继电器超程时间减少对电寿命的影响

提出一种对电磁式继电器可靠性电寿命进行预测的方法,即根据继电器工作中超程时间的减少,通过时间序列回归分析和概率统计分析,对继电器电寿命的预测建立数学模型.预测和实测结果表明该方法的有效性.     

Optical Disks as a Basis of Modern Paperless Data Processing

Potentialities of the methods of information processing, distribution, and storage are analyzed. Directions are defined in which optical information media characteristics can be improved. Possibility of using optical media for a long-term storage of digital information is considered.     

配电网载波通信与链路接入技术

配电网载波通信 ,充分利用电力线自身资源 ,应用简单、方便 ,然而由于配电网自身的复杂性 ,仅依靠单一的调制解调技术———这一物理层功能 ,很难满足配电自动化系统的需要 ,从局域网的角度看配电载波通信 ,分析链路接入技术 ,指出令牌接入技术是适应配电载波通信的接入技术。