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991.
The aim was to investigate the association between building-related symptoms (BRS) in office buildings and the inflammatory potency of dust (PD). Furthermore, the association between dust potency and various building characteristics was investigated. Occupants of 22 office buildings received a retrospective questionnaire about BRS (2301 respondents). Dust was collected from groups of offices and building characteristics were recorded. The potency of a dust sample to induce interleukin-8 (IL-8) secretion from the lung epithelial cell line A549 was measured as the slope of the initial linear part of the concentration-response curve. Symptoms of the central nervous system (CNS) were associated with the potency of surface dust (OR = 1.4). This association may be due to an association between an index of CNS symptoms and dust potency in offices of 1-6 occupants (OR = 1.5). No single symptoms correlated with the potency of surface dust. The PD was not related to single building factors. The inflammatory PD may be used as an integrated proxy measure of biologically active compounds in dust, reflecting health relevant properties of the dust. PRACTICAL IMPLICATIONS: The potency of surface dust may be used as a crude measurement of the chemical and biological exposures present in the building, and being associated with the development of central nervous system symptoms. However, additional research is needed to establish the predictive value of the potency of surface dust. 相似文献
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R.M.L.D. Rathnayake Y. Song A. Tumendelger M. Oshiki S. Ishii H. Satoh S. Toyoda N. Yoshida S. Okabe 《Water research》2013
Emission of nitrous oxide (N2O) during biological wastewater treatment is of growing concern since N2O is a major stratospheric ozone-depleting substance and an important greenhouse gas. The emission of N2O from a lab-scale granular sequencing batch reactor (SBR) for partial nitrification (PN) treating synthetic wastewater without organic carbon was therefore determined in this study, because PN process is known to produce more N2O than conventional nitrification processes. The average N2O emission rate from the SBR was 0.32 ± 0.17 mg-N L−1 h−1, corresponding to the average emission of N2O of 0.8 ± 0.4% of the incoming nitrogen load (1.5 ± 0.8% of the converted NH4+). Analysis of dynamic concentration profiles during one cycle of the SBR operation demonstrated that N2O concentration in off-gas was the highest just after starting aeration whereas N2O concentration in effluent was gradually increased in the initial 40 min of the aeration period and was decreased thereafter. Isotopomer analysis was conducted to identify the main N2O production pathway in the reactor during one cycle. The hydroxylamine (NH2OH) oxidation pathway accounted for 65% of the total N2O production in the initial phase during one cycle, whereas contribution of the NO2− reduction pathway to N2O production was comparable with that of the NH2OH oxidation pathway in the latter phase. In addition, spatial distributions of bacteria and their activities in single microbial granules taken from the reactor were determined with microsensors and by in situ hybridization. Partial nitrification occurred mainly in the oxic surface layer of the granules and ammonia-oxidizing bacteria were abundant in this layer. N2O production was also found mainly in the oxic surface layer. Based on these results, although N2O was produced mainly via NH2OH oxidation pathway in the autotrophic partial nitrification reactor, N2O production mechanisms were complex and could involve multiple N2O production pathways. 相似文献
996.
本文旨在探讨空间构形的内在可读性与在寻路之间的关系。在对常州某区域进行虚拟寻路实验后发现.空间构形的内在可读性在很大程度上影响主体在寻路过程中的表现。笔者相信研究结果对城市设计特别是寻路设计将会有很大帮助。 相似文献
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传统村落有着丰富的自然及历史人文景观,其中蕴藏的生态智慧正是传统村落价值的体现,是村落文化价值认同的根基,也是传统村落保护与传承下去的内在驱动力。以河北省井陉于家石头村为例,分析研究冀南山区传统村落的生态智慧及其价值意义。 相似文献
999.
村落中民居类型文物建筑保护与利用的状况复杂,缓解文物保护与居住使用之间的矛盾,居住者自觉意识的提高等,均需要有大量深入的工作。本文以黄田村古建筑群做为研究对象,基于古民居建筑的历史特色与保护困境,探究民居类文物建筑保护利用导则的方法与思路。 相似文献
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城市化发展及新农村建设对江南传统水乡村落的更新改造产生了严重的冲击,越来越多富有特色的村落在现代化发展中失去它们的历史底蕴与建筑地域文化。本文以文昌村村庄整治规划设计为例,在对该村落历史文化深度挖掘的基础上,利用高铁站“三个圈层”理论确定其功能结构规划及土地利用规划;从自然格局、空间形态、建筑特色等方面探讨保护并重塑村落特色空间的设计手法,为村落改造项目如何合理处理发展与保护的关系提供借鉴。 相似文献