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11.
Alvin W. Nienow 《化学,工程师,技术》2021,93(1-2):17-30
From the start of industrial biotechnology, there has been a perception that biological entities are damaged by stirring, so-called ‘shear damage'. Often, it was the soft option to explain a loss of performance when it was due to other factors, such as bubble ingestion with proteins or on scale-up, where tip speed increased when it was due to decreased homogeneity, especially in pH. For many years, poor control and the range of analytical tools available made a more in-depth explanation difficult; and the concepts of ‘high' and ‘low shear' impellers, now largely disproven, increased it. Here, the size of the biological entity is compared to the Kolmogorov microscale of turbulence leading to a reasonably clear picture emerging. The article starts with the author's introduction to the issue approximately 42 year ago with enzymes, conveniently also the smallest entity; and finishes with the largest, filamentous fungi. 相似文献
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江西省宜春中心城区人口增长速度加快,而现状供水规模偏小,且水源单一,一旦遭遇特枯水年份、连续干旱年或袁河发生重大污染事故,中心城区将面临严重的供水危机,急需寻找第二水源点,加快备用水源的建设. 相似文献
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对于医学图像滤波来说,很重要的一点就是滤波后的图像应该尽可能地保留图像中的边缘和细节特征.但通常在滤波过程中,在消除噪声的同时会模糊图像中一些重要的结构信息.在最近几年中,基于尺度的滤波方法已经有效地应用在灰度图像的滤波中.现把基于尺度的方法推广到矢量(彩色)图像的滤波中.在传统滤波方法(矢量中值滤波、基本矢量方向滤波和方向距离滤波)基础上,相应地提出了3种基于球尺度的矢量滤波器.新的滤波方法能根据图像中像素的尺度信息,在图像边缘和细节附近,即区域边界执行较小的平滑,而在区域内部进行较大的平滑,从而能够自适应地控制滤波过程.实验结果表明,所提出的滤波方法与传统滤波方法相比,在消除噪声的同时更能够保留图像中的边缘和细节特征. 相似文献
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The purpose of this study was to examine individual differences in the effectiveness of learning objects in secondary school classrooms. Specifically, gender, age, grade, subject area, and computer comfort (self-efficacy) were examined in 850 students. Effectiveness was measured in terms of student attitude (learning, quality, and engagement) and student performance. No gender differences were observed between males and females with respect to student attitudes or performance. Age was significantly correlated with student attitudes and performance, however correlation coefficients were small. Grade 12 students were more positive about learning objects and performed better than grade 9 and 10 students. Science students had significantly more positive attitudes and performed better than mathematics students. Finally, students who were more comfortable about computers, appreciated learning objects more than their less confident peers, however performance was unaffected. 相似文献
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Related problems of scaled matching and indexing, which aim to determine all positions in a text T that a pattern P occurs in its scaled form, are considered important because of their applications to computer vision. However, previous results only focus on enlarged patterns, and do not allow shrunk patterns since they may disappear. In this paper, we give the definition and an efficient indexing algorithm for proportionally-scaled patterns that can be visually enlarged or shrunk. The proposed indexing algorithm takes O(|T|) time in its preprocessing phase, and achieves time in its answering phase, where |T|, |P|, Up, and m denote the length of T, the length of P, the number of reported positions, and the length of T under run-length representation, respectively. 相似文献
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We propose a robust Poisson geometric process model with heavy-tailed distributions to cope with the problem of outliers as it may lead to an overestimation of mean and variance resulting in inaccurate interpretations of the situations. Two heavy-tailed distributions namely Student’s t and exponential power distributions with different tailednesses and kurtoses are used and they are represented in scale mixture of normal and scale mixture of uniform respectively. The proposed model is capable of describing the trend and meanwhile the mixing parameters in the scale mixture representations can detect the outlying observations. Simulations and real data analysis are performed to investigate the properties of the models. 相似文献
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基于SIFT特征点匹配的水印图像几何校正算法* 总被引:6,自引:0,他引:6
为了有效实现水印图像的水印检测与水印嵌入之间的同步,提出一种应用SIFT(scale invariant feature transform)特征点匹配估计水印图像几何变换参数的校正算法.用两个稳定而又相距最远的图像SIFT特征点的变化估计图像所经历的旋转和缩放参数,校正之后,再用一个稳定的SIFT特征点的变化校正图像... 相似文献