xOpat: eXplainable Open Pathology Analysis Tool

Histopathology research quickly evolves thanks to advances in whole slide imaging (WSI) and artificial intelligence (AI). However, existing WSI viewers are tailored either for clinical or research environments, but none suits both. This hinders the adoption of new methods and communication between the researchers and clinicians. The paper presents xOpat, an open-source, browser-based WSI viewer that addresses these problems. xOpat supports various data sources, such as tissue images, pathologists' annotations, or additional data produced by AI models. Furthermore, it provides efficient rendering of multiple data layers, their visual representations, and tools for annotating and presenting findings. Thanks to its modular, protocol-agnostic, and extensible architecture, xOpat can be easily integrated into different environments and thus helps to bridge the gap between research and clinical practice. To demonstrate the utility of xOpat, we present three case studies, one conducted with a developer of AI algorithms for image segmentation and two with a research pathologist.     

三维医学可视化分析平台的研究

本文介绍西北大学可视化研究所研制的三维医学可视化分析系统。该系统可用于医学影像数据库、手术计划系统、远程会诊系统和计算机医学辅助教学系统的开发平台,为医学图像可视化提供了有力的工具。     

基于小波的多分辨率贴面算法及实现

贴面是指在两个平行截面的轮廓线间用面片（通常是三角面片）贴补侧面,从而得到一个三维实体的过程,贴面是三维重建的一项内容,有重要的应用价值,例如医学领域由人体器官切片图来重建器官三维模型,地形方面由等高线得到地形等。本文介绍多分辨率贴面算法及其实现技术,并给出了运行实例。     

基于WWW的虚拟并行程序环境的设计与实现

该文提出了一个基于ＷＷＷ的虚拟并行程序环境框架,并且对实现该环境的关键技术如消息传送接口、基于Ｊａｖａ图形用户接口、可视化子系统应用等进行了研究。该环境在大型复杂工程研究开发、远程教育等领域有着重要的应用。     

虚拟现实语言VRML与仿真结果可视化

介绍了虚拟现实语言ＶＲＭＬ的功能及在计算机仿真结果可视化中的应用。讨论了在动态系统仿真软件Ｓｉｍｕｌｉｎｋ中生成的三维仿真结果到ＶＲＭＬ２．０场景数据的转换,及场景文件的自动生成问题,实现了在浏览器中对三维仿真数据的直观显示、观察和理解。     

推理过程的可视化研究

文章利用可视化技术,选择L系统为规则库的形式描述,实现推理的可视化。在知识表示方面,采用图形化的方法—逻辑演绎图,并将可视化因子加入规则。而在反向推理中,采用了模糊推理路径。最后用面向对象的方法实现。     

基于相密度的混沌吸引子可视化方法研究

针对以往混沌子可视化方法法存在的某些局限,提出了相密度定义从而对吸引子在相空间中的分布情况进行了全局性的定量描述,并为混沌吸引子可视化提供了有效的参考与控制,另外,基于相密度实现的混沌吸引子体绘制可视化方法与Lyapunov谱特征可视化方法,还从不同角度揭示了混沌行为的整体变化情况以及局部相空间中混系统的基本特征,并在丰富混沌吸引子可视化内容与形式的同时,降低了可视化过程的复杂性。     

基于OpenGL实现真实感地形表现的研究

三维真实感图形是科学可视化、计算机动画、虚拟现实的技术核心,也是时空一体化地理信息系统的关键技术,而OpenGL又是目前最新的三维图形国际标准,为了实现地形的真实感显示,讨论了三维真实感地形表现在OpenGL支持下的地形模型映、遥感影象与地形的融合、专题信息与地形的融合、以及动画与虚拟现实等技术实现方法,并在荆江分洪区洪水演进模拟系统等开发中得到应用。     

Browsing functions in three-dimensional space for digital libraries

In order to get useful information from various kinds of information sources, we first apply a searching process with query statements to retrieve candidate data objects (called a hunting process in this paper) and then apply a browsing process to check the properties of each object in detail by visualizing candidates. In traditional information retrieval systems, the hunting process determines the quality of the result, since there are only a few candidates left for the browsing process. In order to retrieve data from widely distributed digital libraries, the browsing process becomes very important, since the properties of data sources are not known in advance. After getting data from various information sources, a user checks the properties of data in detail using the browsing process. The result can be used to improve the hunting process or for selecting more appropriate visualization parameters. Visualization relationships among data are very important, but will become too time-consuming if the amount of data in the candidate set is large, for example, over one hundred objects. One of the important problems in handling information retrieval from a digital library is to create efficient and powerful visualization mechanisms for the browsing process. One promising way to solve the visualization problem is to map each candidate data object into a location in three-dimensional (3D) space using a proper distance definition. In this paper, we will introduce the functions and organization of a system having a browsing navigator to achieve an efficient browsing process in 3D information search space. This browsing navigator has the following major functions: ?1. Selection of features which determine the distance for visualization, in order to generate a uniform distribution of candidate data objects in the resulting space. ?2. Calculation of the location of the data objects in 2D space using the selected features. ?3. Construction of 3D browsing space by combining 2D spaces, in order to find the required data objects easily. ?4. Generation of the oblique views of 3D browsing space and data objects by reducing the overlap of data objects in order to make navigation easy for the user in 3D space. ?Examples of this browsing navigator applied to book data are shown. Received: 15 December 1997 / Revised: June 1999     

RectEuler: Visualizing Intersecting Sets using Rectangles

Euler diagrams are a popular technique to visualize set-typed data. However, creating diagrams using simple shapes remains a challenging problem for many complex, real-life datasets. To solve this, we propose RectEuler: a flexible, fully-automatic method using rectangles to create Euler-like diagrams. We use an efficient mixed-integer optimization scheme to place set labels and element representatives (e.g., text or images) in conjunction with rectangles describing the sets. By defining appropriate constraints, we adhere to well-formedness properties and aesthetic considerations. If a dataset cannot be created within a reasonable time or at all, we iteratively split the diagram into multiple components until a drawable solution is found. Redundant encoding of the set membership using dots and set lines improves the readability of the diagram. Our web tool lets users see how the layout changes throughout the optimization process and provides interactive explanations. For evaluation, we perform quantitative and qualitative analysis across different datasets and compare our method to state-of-the-art Euler diagram generation methods.