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61.
通过对饶阳凹陷留107区块断层-岩性油藏的解剖,明确了该类型油气藏的成藏主控因素。留107区块位于饶阳凹陷中部富油气的肃宁构造与大王庄构造的结合部,为东西两侧受断层夹持的NE向单斜构造,储油层为古近系沙河街组一段上亚段-东营组三段三角洲前缘河口坝、分流河道及河流相砂体。留107区块断层-岩性油藏富集程度高,开发效果好,其成藏与富集的关键因素是:①区块西北侧低部位断层在主生排烃期(馆陶组-明化镇组沉积期)持续性活动,沟通了油气源,区块东、西两侧高部位断层在主生排烃期前就停止了活动,起到封挡作用;②小于35%的中低砂/地比和断层与砂体的走向斜交,有利于断层-岩性油藏的形成和富集,并形成平面上多个油藏、纵向上多套层系的成藏特征;③区域性稳定的盖层控制了油气的主要聚集层位。 相似文献
62.
随着集成电路工艺技术的飞速发展,单芯片多处理器(Single-chip Multiprocessor,CMP)结构将是一种有效利用片上晶体管资源、提高系统性能的有效途径.CMP中各个内核通过共享同级存储装置共享数据,如共享一级Cache,共享二级Cache等.可交换数据Cache结构的CMP(Exchangeable Data Cache Architecture,EDCA-CMP)通过交换一级数据Cache的内容共享数据Cache,降低对下级存储的访问延迟,提高数据Cache的命中率,获得较高的性能. 相似文献
63.
在普通ZL107合金中添加0.15%Mg、0.15%Ti、0.15%Cd和1.0%Zn并通过适当热处理后合金的综合力学性能得到显著改善。实验结果表明,舍金成分经优化设计后,力学性能指标为:抗拉强度达361MPa,伸长率达3.65%。采用的515℃固溶处理加150℃时效处理,可使合金的组织细化,得到较好的强韧性配合。在合金中添加0.5%Ag可显著提高伸长率。 相似文献
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Osteoclasts (OCs), which are responsible for bone resorption, play a critical role in cholesterol-induced bone loss and recent studies have suggested that various micro-RNAs (miRs) contribute to modulating OCs. We hypothesized that 7-ketocholesterol (7-KC), a metabolite responsible for cholesterol-induced bone loss, induces miR-107-5p, which affects OCs. Overexpression and knock-down of miR-107-5p were performed using miR-107-5p mimic and anti-miR-107-5p, respectively. The effects of miR-107-5p on OCs were analyzed by tartrate-resistant alkaline phosphatase staining, qPCR, and Western blot. MiR-107-5p was upregulated after 7-KC exposure in receptor activator of nuclear factor kappa-Β ligand-stimulated OCs. Furthermore, miR-107-5p upregulation was also observed in tibiae from an atherogenic diet-fed mice compared with mice fed with a normal diet. MiR-107-5p overexpression enhanced the area and number of OCs, whereas inhibiting the endogenous expression of miR-107-5p generated by 7-KC had the opposite effect. Among the possible candidates, mitogen-activated protein kinase phosphatase-1, a stress-responsive dual-specificity phosphatase that inactivates mitogen-activated protein kinase (MKP1), has been proven to be a target gene of miR-107-5p, as demonstrated by the direct interaction between miR-107-5p and the 3′-untranslated region of MKP1. Collectively, our findings demonstrate that 7-KC-induced miR-107-5p promotes differentiation and function of OCs by downregulating MKP1. 相似文献
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Dietary lipids modulate the expression of miR‐107, a miRNA that regulates the circadian system
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69.
Escherichia coli has been the most popular cellular biofactory for the production of many biomolecules including recombinant proteins whose bioactivities are not dependent on complicated post-translational modifications such as glycosylation. Despite many advantages of protein production using E. coli, the formation of insoluble inclusion bodies (IBs) poses a major challenge to harnessing E. coli as a host of choice. Furthermore, the complicated processing steps associated with IB extraction, solubilisation of IBs and refolding of the solubilised-denatured IB proteins, which are typically encountered in the traditional IB processing flowsheet, significantly compromise process economics of IB-route protein production using E. coli. In this paper, many recent advances in innovative IB processing technologies are reviewed with a special emphasis on their potential to contribute to process intensification, which is critical to achieve better process economics in the IB-route recombinant protein production using E. coli. 相似文献
70.
万迪庆 《中国有色金属学会会刊》2012,22(5):1051-1054
研究ZL107铝合金经过固溶和时效处理后的Si相形态演化及其对力学性能的影响。结果表明,当合金在560°C固溶处理6h后,有部分Si相固溶进入基体,但在随后的时效过程中Si相会重新析出。比较了变质和未变质ZL107合金的固溶时效过程。通过La变质处理再固溶时效,ZL107合金中的Si相形态明显细化,合金的力学性能提高幅度更大。 相似文献