引领潮流的抗衰老化妆品市场

对亚洲及中国的抗衰老化妆品市场进行了论述,并对我国的抗衰老化妆品市场增长的因素进行了分析。介绍了几种抗衰老产品中的新原料以及几种新的抗衰老化妆品品牌。     

高效液相色谱法测定化妆品中苯氧乙醇含量的不确定度评定

目的评定《化妆品中防腐剂的检测方法(征求意见稿)》中高效液相色谱法测定化妆品中苯氧乙醇含量的不确定度。方法依据国家计量技术规范JJF 1059.1-2012《测量不确定度评定与表示》对苯氧乙醇测定中的不确定度来源进行分析。通过建立数学模型量化不确定度分量,计算合成不确定度和扩展不确定度。结果当样品中苯氧乙醇的含量为0.439%时,扩展不确定度为0.016%,苯氧乙醇含量表示为0.439%±0.016%。结论该方法测量化妆品中苯氧乙醇含量的不确定度总体较小,方法相对准确可靠。此次评定的不确定度主要来源为重复性测量、标准曲线配制和样品定容3个方面。     

Advances of Research on Glycinin and β-Conglycinin: A Review of Two Major Soybean Allergenic Proteins

Being an important crop, soybean is widely used in the world and plays a vital role in human and animal nutrition. However, it contains several antinutritional factors (ANFs) including soybean agglutinin, soybean protease inhibitors, soybean allergenic proteins, etc., that may result in poor food utilization, decreased growth performance, and even disease. Among these ANFs, soybean allergenic proteins can lead to allergic reactions in human and animals, which has become a public problem all over the world, but our knowledge on it is still inadequate. This paper aims to provide an update on the characteristics, detection or exploration methods, and in vivo research models of soybean allergenic proteins; especially glycinin and β-conglycinin are deeply discussed. Through this review, we may have a better understanding on the advances of research on these two soybean allergenic proteins. Besides, the ingredient processing used to reduce the allergenicity of soybean is also reviewed.     

毛细管气相色谱法测定植物油脂肪酸组成初探

本研究通过参考文献,直接使用常见油料植物种子制备纯油甲酯进行分析,探讨了快速制备甲酯的试剂选择及用量,强极性和弱极性的两种不同类型毛细管柱的最佳色谱分析条件,并将测定的主要脂肪酸含量与国家标准进行比较,结果较为一致,而且平行测定的相对标准偏差表明方法有较好的精密度和重复性.本论文所测ECL值与文献标准值对照,差别很小,说明本实验操作系统是稳定和可靠的,本研究试图得到一种能够检测大批量样品的简单、快速、准确的植物油脂肪酸组成分析方法.     

Screening commercial available resins for simultaneous removal of two potential genotoxins from API methanolic streams

ABSTRACT

This paper explores potential API loss mitigation during purification in recrystallization mother liquors, by including a resin adsorption step, to remove potential genotoxin impurities (PGTIs). Mometasone furoate (Meta) is used as model active pharmaceutical ingredient (API) in the presence of 4-dimethylaminopyridine (DMAP) and methyl p-toluenesulfonate (MPTS) as two model PGTIs. AG 50W-X2 and IRA68 resins efficiently removed DMAP and MPTS from methanol solutions, respectively, with adsorptions higher than 93% and Meta binding below 2%. Removal of GTIs using these resins sequentially, or combining them in a single step, was also assessed, with superior results for the later approach.

Abbreviations: API, active pharmaceutical ingredient; DMAP, 4-dimethylaminopyridine; DMAP-Me, methylated DMAP; GTI, potential genotoxin impurity; Meta, Mometasone furoate; MPTS, methyl p-toluenesulfonate; PTSA, p-toluenesulfonic acid; TTC, threshold of toxicological concern.     

走出化妆品误区

目前我国化妆品的广告宣传时有制造噱头,夸大其词,致使消费者对化妆品产生不信任。一些对化妆品安全、功效的误解和不科学的简易检验方法应运而生,这极大影响了化妆品行业的健康发展。通过对消费者调查及网上搜索,收集了常见的问题,将其归类,并针对各个常见的错误逐个进行分析,还原化妆品的真相。     

2011年度英国化妆品及个人护理品市场

介绍了英国日化行业的发展状况,对香水,彩妆和护肤品的市场进行了详细的介绍。最后,提出了零售商所面临的问题。     

甘氨酸过氧化钼配合物的合成与表征

以三氧化钼和甘氨酸为原料,采用固液相法制得了甘氨酸过氧化钼(Ⅵ)配合物,并用元素分析、紫外光谱、红外光谱、X射线粉末衍射和热重分析等方法对产物组成和结构进行了表征。结果表明,所合成配合物的组成为[MoO(O2)2(C2H5NO2)].H2O,中心原子钼(Ⅵ)与1个桥氧基氧原子、两个双齿配位的过氧根的4个氧原子、1个甘氨酸中的羧基氧原子形成了六配位的化合物,X射线粉末衍射数据指标化计算证实其晶体结构属于单斜晶系,晶胞参数为:a=1.776 3 nm,b=1.597 2 nm,c=1.967 0 nm,β=89.15°。     

制油工艺对油茶籽油生物活性成分含量和抗氧化活性的影响

为了了解不同制油工艺对油茶籽油生物活性成分含量和抗氧化活性的影响,以油茶果为原料,采取鲜榨法、浸提法、新水法、冷榨法和热榨法5种制油工艺分别制取油茶籽油,研究对比了5种制油工艺的提油率,所制取的油茶籽油的脂肪酸组成、生物活性成分(生育酚、角鲨烯及多酚)含量及其对DPPH自由基和ABTS自由基的清除能力。结果表明,5种制油工艺的提油率均在73%以上,其中浸提法（（96.45±3.02）%）最高,冷榨法（（73.72±2.76）%）最低,鲜榨法（（82.36±224）%）、新水法（（81.91±3.21）%）和热榨法（（80.34±2.09）%）没有显著差异;5种工艺所制取的油茶籽油具有相似的脂肪酸组成;在α-生育酚和总生育酚含量方面,新水法制取的油茶籽油含量最高（α-生育酚含量（263.77±1.58）mg/kg,总生育酚含量（280.55±1.64）mg/kg）,鲜榨法、冷榨法和热榨法制取的油茶籽油中总生育酚含量接近,在233~244 mg/kg之间,浸提法制取的油茶籽油中总生育酚含量只有（17.10±0.76）mg/kg;在角鲨烯和多酚含量方面,鲜榨法制取的油茶籽油明显高于其他工艺的,分别为（350.56±7.60）mg/kg和（45.04±4.50）mg/kg,新水法制取的油茶籽油角鲨烯含量最低,为（249.99±3.73）mg/kg,浸提法制取的油茶籽油多酚含量最低,为（706±003）mg/kg ;在清除DPPH 自由基和ABTS自由基方面,鲜榨法制取的油茶籽油的清除能力最强,浸提法的最弱。