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101.
Ling Yin Eric Y. J. Vancoille Kuppuswamy Ramesh Han Huang 《International Journal of Machine Tools and Manufacture》2004,44(6):607-615
Surface characterization of 6H-SiC (0001) substrates in indentation and abrasive machining was carried out to investigate microfracture, residual damage, and surface roughness associated with material removal and surface generation. Brittle versus plastic deformation was studied using Vickers indention and nano-indentation. To characterize the abrasive machining response, the 6H-SiC (0001) substrates were ground using diamond wheels with grit sizes of 25, 15 and 7 μm, and then polished with diamond suspensions of 3 and 0.05 μm. It is found that in indentation, there was a scale effect for brittle versus plastic deformation in 6H-SiC substrates. Also, in grinding, the scales of fracture and surface roughness of the substrates decreased with a decrease in diamond grit size. However, in polishing, a reduction in grit size of diamond suspensions gave no significant improvement in surface roughness. Furthermore, the results showed that fracture-free 6H-SiC (0001) surfaces were generated in polishing with the existence of the residual crystal defects, which were associated with the origin of defects in single crystal growth. 相似文献
102.
矿岩粉碎全过程能耗-粒度关系的连续损伤理论研究SCIEI 总被引:1,自引:0,他引:1
本文从连续损伤理论的观点出发,将矿岩粉碎过程描述为在外部荷载作用下矿岩颗粒内部微缺陷(损伤)演化和繁衍的过程。导出了粉碎能耗与产品粒度分布的理论表达式。该式包含了所有传统的理论,同时较传统的能量分配观点前进了一步。 相似文献
103.
Miaomiao Shen Yanshen Nie Yueyue Chen Xiufeng Zhang Jie Zhao 《International journal of molecular sciences》2021,22(1)
Meiotic recombination 11 (Mre11) is a relatively conserved nuclease in various species. Mre11 plays important roles in meiosis and DNA damage repair in yeast, humans and Arabidopsis, but little research has been done on mitotic DNA replication and repair in rice. Here, it was found that Mre11 was an extensively expressed gene among the various tissues and organs of rice, and loss-of-function of Mre11 resulted in severe defects of vegetative and reproductive growth, including dwarf plants, abnormally developed male and female gametes, and completely abortive seeds. The decreased number of cells in the apical meristem and the appearance of chromosomal fragments and bridges during the mitotic cell cycle in rice mre11 mutant roots revealed an essential role of OsMre11. Further research showed that DNA replication was suppressed, and a large number of DNA strand breaks occurred during the mitotic cell cycle of rice mre11 mutants. The expression of OsMre11 was up-regulated with the treatment of hydroxyurea and methyl methanesulfonate. Moreover, OsMre11 could form a complex with OsRad50 and OsNbs1, and they might function together in non-homologous end joining and homologous recombination repair pathways. These results indicated that OsMre11 plays vital roles in DNA replication and damage repair of the mitotic cell cycle, which ensure the development and fertility of rice by maintaining genome stability. 相似文献
104.
Mohd N. Mat Nor Ilva D. Rupenthal Colin R. Green Monica L. Acosta 《International journal of molecular sciences》2021,22(4)
Dysregulation of retinal function in the early stages of light-induced retinal degeneration involves pannexins and connexins. These two types of proteins may contribute to channels that release ATP, leading to activation of the inflammasome pathway, spread of inflammation and retinal dysfunction. However, the effect of pannexin channel block alone or block of both pannexin channels and connexin hemichannels in parallel on retinal activity in vivo is unknown. In this study, the pannexin channel blocker probenecid and the connexin hemichannel blocker tonabersat were used in the light-damaged rat retina. Retinal function was evaluated using electroretinography (ERG), retinal structure was analyzed using optical coherence tomography (OCT) imaging and the tissue response to light-induced injury was assessed immunohistochemically with antibodies against glial fibrillary acidic protein (GFAP), Ionized calcium binding adaptor molecule 1 (Iba-1) and Connexin43 (Cx43). Probenecid did not further enhance the therapeutic effect of connexin hemichannel block in this model, but on its own improved activity of certain inner retina neurons. The therapeutic benefit of blocking connexin hemichannels was further evaluated by comparing these data against results from our previously published studies that also used the light-damaged rat retina model. The analysis showed that treatment with tonabersat alone was better than probenecid alone at restoring retinal function in the light-damaged retina model. The results assist in the interpretation of the differential action of connexin hemichannel and pannexin channel therapeutics for potential treatment of retinal diseases. 相似文献
105.
X. W. Zhao J. H. Luo M. Zheng M. X. Lu H. L. Li 《Metals and Materials International》2002,8(5):479-485
Considering such practical pipeline service conditions in the petroleum transportation field as corrosion from harmful media
(H2S, CO2 etc.) and load from the pressure of flowing petroleum as key factors, the degradation of the mechanical properties of pipeline
steels and the corresponding variations in stress states are studied. A damage variable is introduced to reflect the degradation
in the mechanical properties of the pipeline due to corrosion. A diluted solution approach is proposed to model the corrosion
process of harmful media within the pipeline and the distribution of the damage variable along the radial direction of the
pipeline is derived. An approach to the safety evaluation of damaged pipeline is proposed by comparing the instant properties
of pipeline steels with servicing conditions. 相似文献
106.
X2 0CrMoV12 1耐热合金钢广泛应用于热电厂主蒸汽管线等主要部件。经长期高温负荷运行后 ,材料性能明显退化。观察显微组织发现 ,材料性能下降是和晶界碳化物的粗化密切相关的。文章着重研究了损伤材料重新热处理后的性能和组织结构的变化 ,初步探讨了材料长期服役后通过热处理恢复其原始性能的可能性 相似文献
107.
讨论用数值模拟预测板材成形中发生拉深损伤破坏的两种不同的求解方法。第一种是采用完全耦合的弹塑性破坯模型的动力显式数值方法。基于状态参量的不可逆热力学过程 ,完全耦合的本构方程考虑各向同性强化和拉深。这些已引入有限元软件ABAQUS/E用于对金属成形的模拟。在数值技术方面 ,隐式积分方法被用来对本构方程的局部时间积分 ,动力显式技术用于求解总体平衡方程。第二种方案是采用简化的损伤模型的方法 ,被称为逆法 (InveseApprch)。I.A被限定在考虑各向同性强化和损伤的塑性全量理论基础上的简单的本构关系。做比例加载和临界损伤达到以后的损伤饱和假定 ,可以得到损伤演化方程的封闭解。这两种损伤模型在编程中的实施采用两种方式 :计算中考虑或不考虑损伤作用 ,也就是耦合的或非耦合的计算。文中给出一些算例来说明每种损伤模型的优点 相似文献
108.
高水头泄水建筑物侧墙掺气减蚀特性研究 总被引:9,自引:1,他引:8
工程中通常采用强迫掺气减蚀措施,防止泄水建筑物在高速水流作用下发生空蚀破坏,但在保护过流面底板的同时,忽视了对其侧墙的保护。为了减免位于高流速区域和低压区域侧墙发生空化空蚀,消除侧墙清水区,采用理论分析和物理模型试验研究方法,对龙抬头明流泄洪洞下游边墙掺气减蚀进行了研究,提出了在反弧末端加折流器(突扩)和突跌掺气方式。结果表明,采用突扩和突跌的掺气方式后,侧墙水流的出射角增大,侧空腔畅通,并直接和底空腔相连,有助于掺气坎后水舌的全断面的掺气,对侧墙和底板皆起到了很好的保护作用。 相似文献
109.
桥梁健康监测中损伤特征提取的小波包方法 总被引:2,自引:0,他引:2
针对桥梁健康监测中结构损伤识别的特点,从模式识别的角度提出和分析了损伤特征提取问题.阐述了基于小波包分析的两种节点能量特征提取的方法.为了研究小波包系数节点能量和小波包信号成分节点能量对损伤信息进行特征提取的差异,通过对随机荷载激励下的连续梁进行数值模拟,得到了结构未损和损伤状态下的加速度时程信号.应用小波包变换,对不同结构状态下的加速度信号分别提取了两种小波包节点能量特征,并对它们作为结构损伤特征指标的敏感性进行了比较.认为两种特征指标的敏感性相差很小,而小波包系数节点能量特征指标的计算效率更高,更适合桥梁健康监测中损伤特征提取的要求. 相似文献
110.
超高性能混凝土(UHPC)与正交异性钢桥面板的组合是近年来桥梁工程中新材料、新构造研究的典型范例。UHPC桥面板的刚度较大,可以有效减小桥面板中的局部变形,从而明显降低正交异性钢桥面板中的疲劳应力幅,改善其抗疲劳性能。从新构造、剪力连接件性能、组合桥面板基本力学性能、组合桥面板疲劳性能及UHPC材料与构件力学性能等几个方面对UHPC-正交异性钢桥面板组合体系的研究进展进行综述,其内容主要为2020年以来发表的工作,部分兼及更早的研究成果。 相似文献