均匀设计在遗传算法中的应用研究

通过分析均匀设计和遗传算法的内在关系，指出从某个角度上可以把均匀设计看作是遗传算法的一种特例，并针对遗传算法初始参数众多、难配置的问题，提出了利用均匀设计优化配置选择参数的方法，在一定程度上可以避免遗传算法参数配置的盲目性．仿真试验结果证明了该方法是合理、可行的。     

基于遗传算法的图像边缘信息链表匹配技术

提出了一种基于遗传算法的图像边缘信息链表匹配方法。首先,采用CANNY算子的方法提取图像边缘;然后,将图像边缘信息链表化;最后,基于链表化结果利用遗传算法进行链表匹配。该方法能够减少匹配过程中的计算量,且能实现高效匹配。通过仿真实验,验证了该方法的性能。     

基于混合遗传算法的树状注水管网拓扑优化

以投资最小为目标函数,以井间隶属关系的惟一性、连接注水井数量等限制为约束条件,建立了树状注水管网拓扑优化数学模型.根据模型特点,将优化问题分为分配层和几何层,分别采用遗传算法和非线性优化方法进行求解.并对遗传算法的操作过程进行了改进,调整了适应函数,采用随机多父辈适应函数值加权交叉和多种变异操作,结合了模拟退火算法,并给出了初温的确定方法,改进了选择复制操作,从而形成了混合遗传算法.该算法能够有效地提高收敛速度,避免早熟收敛.利用算例说明了该方法的有效性.     

Design optimization of 3D steel structures: Genetic algorithms vs. classical techniques

In this paper an elitist genetic algorithm (GA) developed by the authors is compared with common commercial solutions for complex structural optimization. After its prior validation on two-dimensional (2D) structures, the GA was tuned and improved in order to obtain structural elements with minimum weights that satisfy the ultimate limit states of the applicable building code. Subsequently, the same spatial structures were optimized using a commercial structural analysis program. Finally, the cost and weight improvements obtained using the GA, although at a higher computational cost, are discussed.     

基于Petri网的供需链设计优化研究

供需链设计优化问题由于其自身的复杂性而成为一个极具挑战性的研究课题。本文把Petri网与遗传算法结合起来，用于研究供需链设计优化，构建一个供需链原型测试系统，并对小汽车制造供需链系统进行了实例分析。     

小生境遗传算法AVOA反演

采用具有水平对称轴的横向各向同性(HTI)模型研究裂缝性油气藏,P波振幅随炮检距和方位角变化(AVOA),表现出较强的方位各向异性特征。本文基于Ruger提出的HTI介质模型的P波反射系数公式,利用由基准测线和另外两条与之呈45°、90°测线的P波反射系数的相对差异估算裂缝方位;同时引入小生境遗传算法,对基准测线和与之呈90°测线的P波反射系数差进行反演,得到了较高精度的纵、横波波速比和Thomsen各向异性参数。     

Genetic algorithms for optimal logical database design

The focus of this paper is database design using automated database design tools or more general CASE tools. We present a genetic algorithm for the optimization of (internal) database structures, using a multi-criterion objective function. This function expresses conflicting objectives, reflecting the well-known time/space trade-off. This paper shows how the solution space of the algorithm can be set up in the form of tree structures (forests), and how these are encoded by a simple integer assignation. Genetic operators (database transformations) defined in terms of this encoding behave as if they manipulate tree structures. Some basic experimental results produced by a research prototype are presented.     

聚乙二醇修饰的蓖麻毒蛋白A链的免疫原性和在小鼠体内急性毒性研究

目的研究单甲氧聚乙二醇(mPEG)与蓖麻毒蛋白A链(RA)偶联后RA免疫原性和毒性的改变。方法从天然蓖麻籽中提取纯化的RA,经与含活性马来酰亚胺基团的mPEG反应偶联,得到纯化的mPEG偶联RA。用蛋白质印迹方法比较RA修饰前后的免疫原性,通过测定半数致死量(LD50)比较RA修饰前后的毒性。结果mPEG偶联RA后免疫原性和毒性均明显下降。偶联前RA链的LD50为2.37 mg.kg-1,经mPEG修饰后RA的LD50为6.15mg.kg-1。结论聚乙二醇能遮蔽RA,降低其免疫原性和毒性。     

MALTING AND BREWING SCIENCE: CHALLENGES AND OPPORTUNITIES*,†

Molecular technologies have been developed for the transformation of barley. These technologies complement current methods of barley breeding. In addition, they offer the potential of altering specific components in barley that affect malting quality and of introducing foreign genes, controlling desirable traits, into barley. Application of genetic engineering to improving malt quality factors such as cell wall degradation, protein modification, starch hydrolysis and flavour stability, is discussed. Limitations to the use of this technology for improving malt-related functional properties of barley components such as cell walls and starch granules are also evaluated. Some possible constraints to the utilization of genetic engineering for malt quality improvements are identified.     

The biodegradability of two primary alcohol ethoxylate nonionic surfactants under practical conditions,and the toxicity of the biodegradation products to rainbow trout

A field trial has been performed to measure the biodegradability of two typical alcohol ethoxylate nonionic surfactants, “Dobanol” 45-7 and “Dobanol” 45-11, by dosing them to biological filters in a mixture with domestic sewage. Influent levels were 10 and 25 mg l^?1 of each surfactant and 96–98% degradation was achieved within a temperature range of 5–10°C. The surfactants had no adverse effects on the filters in terms of the usual sanitary parameters (BOD, COD, TOC and ammoniacal nitrogen). Tests on the effluents indicated no residual acute lethal toxicity to rainbow trout Salmo gairdneri).