基于交流比例积分控制器的单相逆变器

提出一种电感电流、输出电压瞬时值反馈控制和负载电流前馈控制相结合的复合控制策略。在此基础上,研制了一台800W的单相逆变器。实验结果表明,提出的控制策略改善了逆变器输出电压的波形,提高了系统的暂态特性。     

基于Java点对点通信技术的DES密钥交换

介绍了使用Java的点对点通信技术,基于Diffie-Hellman规则,给出了IBM DES密钥交换的总体方案、算法和应用程序,详细说明了其中涉及的主要技术和方法,同时给出了在PC机上用二进制指数分解法实现大数模运算的算法分析和实现方案。     

Beller-Yacobi协议的研究与模拟实现

本文着重分析了Beller-Yacobi协议及以其中用到的RSA加解密及签名算法,并以RSA加解密算法为例在.NET环境下使用C#语言模拟实现了其详细过程,最终实现了整个Beller-Yacobi密钥传输协议的过程。     

车载自组网中一种支持群签名认证的分布式密钥管理方案

群签名具备良好的匿名认证特性,满足车载自组网信息安全和隐私保护需求。但是,其作废开销较大,不适于在大规模网络环境中应用。为此,本文提出了一种支持群签名认证的分布式密钥管理方案DKM,将车载自组网的覆盖区域划分为若干子区域,车辆周期性地从所在子区域的群管理机构更新群密钥。这样,作废某个成员只需要在其拥有合法密钥的子区域内通告,而不是整个网络,有利于降低作废开销。同时,DKM中的密钥更新机制能够保证车辆的群密钥的私密性,从而避免了车辆与区域群管理机构的授权争议,保持了数字签名的不可否认性。性能分析表明DKM能够显著缩短作废列表长度,同时没有增加认证开销。     

Identification of Cyclophilin A as a Potential Anticancer Target of Novel Nargenicin A1 Analog in AGS Gastric Cancer Cells

We recently discovered a novel nargenicin A1 analog, 23-demethyl 8,13-deoxynargenicin (compound 9), with potential anti-cancer and anti-angiogenic activities against human gastric adenocarcinoma (AGS) cells. To identify the key molecular targets of compound 9, that are responsible for its biological activities, the changes in proteome expression in AGS cells following compound 9 treatment were analyzed using two-dimensional gel electrophoresis (2-DE), followed by MALDI/TOF/MS. Analyses using chemical proteomics and western blotting revealed that compound 9 treatment significantly suppressed the expression of cyclophilin A (CypA), a member of the immunophilin family. Furthermore, compound 9 downregulated CD147-mediated mitogen-activated protein kinase (MAPK) signaling pathway, including c-Jun N-terminal kinase (JNK) and extracellular signal-regulated protein kinase 1/2 (ERK1/2) by inhibiting the expression of CD147, the cellular receptor of CypA. Notably, the responses of AGS cells to CypA knockdown were significantly correlated with the anticancer and antiangiogenic effects of compound 9. CypA siRNAs reduced the expression of CD147 and phosphorylation of JNK and ERK1/2. In addition, the suppressive effects of CypA siRNAs on proliferation, migration, invasion, and angiogenesis induction of AGS cells were associated with G2/M cell cycle arrest, caspase-mediated apoptosis, inhibition of MMP-9 and MMP-2 expression, inactivation of PI3K/AKT/mTOR pathway, and inhibition of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) expression. The specific interaction between compound 9 and CypA was also confirmed using the drug affinity responsive target stability (DARTS) and cellular thermal shift assay (CETSA) approaches. Moreover, in silico docking analysis revealed that the structure of compound 9 was a good fit for the cyclosporin A binding cavity of CypA. Collectively, these findings provide a novel molecular basis for compound 9-mediated suppression of gastric cancer progression through the targeting of CypA.     

面向工业平稳/非平稳复杂系统的在线故障监测技术

针对复杂系统中关键性能指标（KPI）相关故障检测方法检测精度低的问题,提出基于双层改进潜结构投影（DL-IPLS）的KPI相关故障检测方法. 利用协整分析和主元分析建立底层模型,对非平稳和平稳变量进行特征提取. 将提取的信息进行融合,建立改进潜结构投影的上层模型,根据融合信息对KPI的贡献进行空间分解. 在2个正交子空间中设计统计量,实现KPI相关故障的在线监测. 田纳西-伊斯曼过程和青霉素发酵过程的仿真结果表明,在面向工业平稳和非平稳复杂工业系统检测时,所提方法有效提高了KPI相关故障的检测率,降低了KPI无关故障的误报率.     

WAVE FIELD EXTRAPOLATION IN VISCOELASTIC MEDIUM AND VARIABLE FOCUS METHOD TO SEPARATE SEISMIC COMPOUND WAVE

ＷＡＶＥＦＩＥＬＤＥＸＴＲＡＰＯＬＡＴＩＯＮＩＮＶＩＳＣＯＥＬＡＳＴＩＣＭＥＤＩＵＭＡＮＤＶＡＲＩＡＢＬＥＦＯＣＵＳＭＥＴＨＯＤＴＯＳＥＰＡＲＡＴＥＳＥＩＳＭＩＣＣＯＭＰＯＵＮＤＷＡＶＥ￥ＳｏｎｇＳｈｏｕｇｅｎ；ＹｕａｎＸｉｕｇｕｉ；ＨｅＪｉｓｈａｎ...     

化工过程熵增指数及其在磷复肥清洁生产评价中的应用

从热力学第二定律出发, 指出清洁生产的热力学本质是控制物质由有序结构向无序转化并从中获取最大效益, 其优劣可由过程熵增反映。 引用复杂体系非平衡定态过程最小熵产生原理,推导出依据与外界交换的物流和热流信息定量计算化工复杂系统过程熵增的方法, 并定义过程熵增指数ζ 。 评价了化工过程对环境热力学状态的综合影响。选择以硫和以氨为载能原料的磷复肥工艺为例进行了计算和对比,其过程熵增指数分别为6.753和4.571,反映出载能原料硫作为废物排放对环境热力学状态产生更大的影响。     

30%三唑锡悬浮剂的研制及作用机理分析

[目的]解决30%三唑锡悬浮剂分散稳定性的问题。[方法]为提高30%三唑锡悬浮剂分散稳定性,采用流点法对不同类型的分散剂进行初步筛选并测试表面张力,通过测试SC粒径、Zeta电势、悬浮率、流变性能确定分散剂配比与用量并对分散稳定机理进行分析。[结果]与单一分散剂制备SC相比,聚羧酸盐分散剂SD-816和聚氧乙烯醚磷酸酯分散剂SD-208复配体系制备的SC性能较优,其表观黏度、Zeta电势、粒径和悬浮率分别为386 mPa·s、-37.2 mV、2.58μm及98.4%。并且提出了聚羧酸盐分散剂和聚氧乙烯醚磷酸酯分散剂对农药三唑锡可能的分散机理。[结论]聚羧酸盐SD-816和聚氧乙烯醚磷酸酯SD-208的复配体系可同时提供静电排斥作用和空间位阻,明显改善SC体系的悬浮稳定性。     

大型非周期相控阵天线协同设计

针对大型非周期相控阵天线的特点,提出一种多学科、多领域协同设计的方法。然后运用该方法指导两个产品天线设计,围绕协同设计的典型流程和几个关键控制点展开论述。在测试阶段实测天线的主要指标,天线1辐射端面平面度≤1.4 mm,栅瓣电平≤-20 dB,天线2辐射端面平面度≤1.1 mm,栅瓣电平≤-18 dB,实测数据与仿真结果吻合,各项指标优于设计输入要求,使用性能良好,验证协同设计方法的有效性。最后指明大型非周期相控阵天线协同设计的进一步研究方向。