A NEW BATO COMPLEX^99mTcCl（4—MCDO）3MeB FOR MYOCARDIAL IMAGING

A new nertral complex,^99mTcCl(4-MCDO)3MEB,((Bis[4-methyl-1,2-cyclohex-anedionedioximato(1-)-O]-[4-methyl-1,2-cyclohexanedione-dioximato(2-)-O] methyl-borato(2-)-N,N‘,N″,N‘‘‘,N‘‘‘‘0-chlorotechnetium,generally called BATO(Boronic acid adducts of technitium dioximes),has been synthesized and evaluated for potential use in myocardial perfusion imaging,It has intrinsic affinity for the blood clearance.The uptake of heart.lung and blood in mice at 2min separately are 1.12,2.48 and 6.66%ID.The complex formation is rapid,simple and highly yielded(≥93%).This process is easy to kit formation.     

脱水过程中无核白葡萄转录组测序及膜脂降解代谢中关键基因的筛选

该研究以吐鲁番地区无核白葡萄为试验材料,在25 ℃常温和30 ℃热风干燥后,取失水25%、50%时褐变和未褐变的样品。利用转录组测序技术筛选出膜脂降解代谢相关的关键基因,并利用实时荧光定量PCR技术对其进行验证,研究结果显示,转录组测序共获得了11.63亿的clean data,当无核白失水50%时未褐变与褐变的相比,在快速脱水组筛选出718个差异表达基因,慢速脱水组2 259个。将上述基因进行GO功能富集和KEGG富集分析后,筛选出43个膜脂代谢相关的差异基因,归类于5种代谢途径。从已获得的差异基因中最终筛选出乙醛脱氢酶7B4（Aldehyde Dehydrogenase7B4,ALDH7B4）、双半乳糖甘油二酯合成酶1（Digalactose Diglycerol Synthetase1,DGD1）、脂氧合酶（Lipoxygenase,LOX）、磷脂磷酸水解酶2（Lipid Phosphate Phosphatase2,LPP2）、二酰基甘油激酶5（Diacylglycerol Kinase5,DGK5）、非特异性磷脂酶C4（Non-specific Phospholipase C4,NPC4）、磷脂酶Dα1（Phospholipase Dα1,PLDα1）7个膜脂代谢相关的关键基因,经qRT-PCR验证,基因表达趋势与转录组测序结果基本一致。结果表明,膜脂降解代谢相关基因表达量变化对无核白脱水褐变有一定影响。     

A primary influence vertex approach to identify driving factors in complex integrated agri-industrial systems – an example from sugarcane supply and processing systems

Integrated agri-industrial systems (IAISs), such as sugarcane supply and processing systems, are complex systems and hence generally difficult to understand and manage. The large number factors in IAISs coupled with the complex interrelationships among the factors make it challenging to identify the points of intervention for improving their overall performance. Several approaches, such as the network theory and the Theory of Constraints have been used to identify important factors in systems with variations in success. This paper demonstrates a primary influence vertex approach for identifying and ranking the factors that drive the performance of IAISs. The approach is based on comprehensive causal network analyses and was tested in four relatively diverse large-scale sugarcane milling operations in South Africa. Results from the analyses were found to be consistent with the literature and external knowledge of the milling areas as at the time of the study. It is concluded that the approach can proffer a sound basis from which deeper rooted problems in systems can be identified on an ongoing basis. It is, however, recommended that the approach should be systematically compared with other relevant methods that are used to analyse complex systems.     

Seismic response and stability of underground rock caverns: a case study of Baihetan underground cavern complex

The seismic stability of the underground cavern complex, which houses the Baihetan hydropower plant in Yunnan Province, China, currently the world’s 2nd largest underground rock cavern group, is studied in this article. A preliminary performance-based seismic assessment approach specified for underground rock caverns is firstly proposed. The seismic performance objectives are classified. Reference earthquake motions are specified with the determination of the seismic variables. Detailed dynamic response analyses (Method 2B) are conducted based on the parameters given by the cyclic dynamic loading tests with medium strain rate. The seismic response of acceleration, stress, displacement and failure zones are studied. In addition, the seismic spectrum characteristics are analysed with a newly introduced wavelet packet technique. The mechanism of the support measures for seismic stability is also discussed. The assessment for seismic performance of the underground cavern complex is obtained by integrating these results. Serviceability objective of the underground cavern complex under operating basis earthquake may be satisfied, and the safety objective be feasible but with the presence of the proposed reinforcement system. The seismic isolation design is preferred, yet not necessary. And if any seismic isolation design is to be adopted, the frequency absorption range of the isolation material is expected to be 1–4 Hz.     

Development of a water-in-oil-in-water multiple emulsion system integrating biomimetic aqueous-core lipid nanodroplets for protein entity stabilization. Part II: process and product characterization

The aqueous-core enclosed in lipid nanoballoons integrating multiple emulsions of the type water-in-oil-in-water mimic, at least in theory, the environment within viable cells, thus being suitable for housing hydrophilic protein entities such as bioactive proteins, peptides and bacteriophage particles. This study reports a complete physicochemical characterization of optimized biomimetic aqueous-core lipid nanoballoons housing hydrophilic (BSA) protein entities, evolved from a statistical 2³×3¹ factorial design study (three variables at two levels and one variable at three levels) that was the subject of the first paper of a series of three, aiming at complete stabilization of the three-dimensional structure of protein entities attempted via housing the said molecular entities within biomimetic aqueous-core lipid nanoballoons integrating a multiple (W/O/W) emulsion. The statistical factorial design followed led to the production of an optimum W/O/W multiple emulsion possessing quite homogeneous particles with an average hydrodynamic size of (186.2?±?2.6) nm and average Zeta potential of (?36.5?±?0.9) mV, and exhibiting a polydispersity index of 0.206?±?0.014. Additionally, the results obtained for the diffusion coefficient of the lipid nanoballoons integrating the optimized W/O/W multiple emulsion were comparable and of the same order of magnitude (10^?12 m² s^?1) as those published by other authors since, typically, diffusion coefficients for molecules range from 10^?10 to 10^?7 m² s^?1, but diffusion coefficients for nanoparticles are typically of the order of magnitude of 10^?12 m² s^?1.     

石墨烯改性双噻唑聚合物及其配合物的合成与性能

合成了一种含功能化石墨烯的双噻唑聚合物(SDS-GNS)及其配合物SDS-GNS-Cu2+,利用红外光谱、X射线衍射分析等对其结构进行了表征;通过综合热分析得出SDS-GNS和SDS-GNS-Cu2+的失重速率分别为4.8%/℃和5.7%/℃,说明聚合物SDS-GNS和配合物SDS-GNS-Cu2+具有较好的热稳定性;通过常温测定聚合物SDS-GNS和配合物SDS-GNSCu2+的电化学特性,采用交流阻抗拟合方法,获得SDS-GNS和SDS-GNS-Cu2+的电导率分别为2.03×10-6S/cm和2.32×10-6S/cm。     

复杂环境下高危双曲线冷却塔爆破拆除

针对在复杂环境下一座高86 m的冷却塔,其部分塔壁、圈梁和人字柱已被机械拆除损毁的特殊结构特点,运用定向爆破技术拆除高危冷却塔。在确保结构稳定和不造成二次破坏的情况下,利用机械开设高减荷槽、定位窗和泄压窗等措施,以损毁部分塔壁作为爆破切口为基础,对爆破切口内的人字柱、圈梁进行爆破;运用ANSYS/LS-DYNA建立分离式共节点模型,对其倒塌过程进行数值模拟,进而对爆破方案进行验证并为其优化提供参考。     

微镁处理对铸态低碳钢中夹杂物和组织的影响

在实验室条件下,对低碳钢进行微镁处理,以SEM-EDS和金相显微镜为表征手段,通过与空白样的对比,研究钢中夹杂物、组织的演变过程。结果表明:微镁处理使得夹杂物从Al_2O_3转变为Mg-Al-O复合夹杂物,并且其尺寸明显细化,密度显著增加。组织分析表明:Mg-Al复合夹杂物能够诱导晶内针状铁素体形核,并且在这些夹杂物附近的铁基体中存在贫锰区。理论分析认为这促进了晶内针状铁素体的形核,结晶核心起源于复合夹杂物中镁铝尖晶石的镁空位。     

浅析小麦种植标准综合体构建

本文采用综合标准化的原理和方法,对标准化对象和目标进行了分析,阐述了影响小麦产量和质量的因素,确定了相关要素图,构建了小麦种植标准综合体结构框架.本研究可以为推进综合标准化方法的应用提供参考,有助于发挥标准化对小麦高产优质的技术支撑作用.     

Light‐Activated,Multi‐Semiconductor Hybrid Microswimmers

Using a dynamic fabrication process, hybrid, photoactivated microswimmers made from two different semiconductors, titanium dioxide (TiO₂) and cuprous oxide (Cu₂O) are developed, where each material occupies a distinct portion of the multiconstituent particles. Structured light‐activated microswimmers made from only TiO₂ or Cu₂O are observed to be driven in hydrogen peroxide and water most vigorously under UV or blue light, respectively, whereas hybrid structures made from both of these materials exhibit wavelength‐dependent modes of motion due to the disparate responses of each photocatalyst. It is also found that the hybrid particles are activated in water alone, a behavior which is not observed in those made from a single semiconductor, and thus, the system may open up a new class of fuel‐free photoactive colloids that take advantage of semiconductor heterojunctions. The TiO₂/Cu₂O hybrid microswimmer presented here is but an example of a broader method for inducing different modes of motion in a single light‐activated particle, which is not limited to the specific geometries and materials presented in this study.