标杆管理的精髓及其应用的探讨

本文从理论的视角对标杆管理的精髓进行了探讨,从实践的结果对标杆管理在电力勘察设计行业及其企业中的应用进行了分析,对应用中出现的主要问题提出了建议。     

配电网可靠性评估方法的研究

将树的操作方法融入到馈线分区和网络等值的思想中,提出一种能快速实现复杂配电网可靠性评估的分区等值法.首先运用改进的后序遍历法快速形成最小故障区,在故障解析时以最小故障区为单位进行向上和向下等效.在等效过程中利用最小故障区中根节点承上启下的作用,将各区之间的故障影响关系用根节点的等效参数来表示,从而解决了馈线分区,等效节...     

基于POE研究的城市公园规划设计——以橘子洲公园为例

国内传统城市公园规划设计多从景观美学以及游憩的角度作为规划与经营的方向,大都以决策者为导向的方式进行,而对于是否符合使用者的需求以及发展的原则并没有太多的着墨。本文以长沙橘子洲公园为例,从景观设计维护、人际关系、休憩设施、厕所满意度、自然生态水池满意度五个方面对公园进行POE研究,并在此基础上提出规划改造策略与建议,为创造生态活力、“以人为本”的城市公园提供依据。     

后压浆方案的技术可行性论证

从地层选择、效果预测、经济分析和施工应用４个方面对钻孔灌注桩后压浆方案进行可行性论证，并对承载力增幅进行了分析。     

Post mortemRelease of Fish White Muscle α-Actinin as a Marker of Disorganisation

α-Actinin release and its degradation from myofibrils Z-line were studied in post mortem white dorsal muscle from bass and sea trout stored at 4°C and 10°C. Using α-actinin specific antibodies, we show that this protein is rapidly released within the first 24 h for the two species, and reaches a plateau within 4 days. Proteolysis take place very rapidly in bass muscle yielding 80 and 40 kDa fragments from α-actinin as major bands of proteolysis. Sea trout muscle is more resistant, and muscle stored at 4°C is not significantly α-actinin degraded even 10 days after death. In the case of sea trout muscle stored at 10°C, an increasing quantity of 80 and 40 kDa fragment can be observed after the third day. These results show that release and proteolysis of α-actinin are time- and temperature-dependent processes that take place at the early stages of fish storage. Furthermore, we observed that proteolysis of α-actinin seems to be dependent on fish species. In both species studied, the early release of α-actinin comes before the degradation of released molecules, and appears as a biphasic process throughout the disorganisation of post mortem muscle in fish cold-stored above 0°C.     

Fundamental Clock of Biological Aging: Convergence of Molecular,Neurodegenerative, Cognitive and Psychiatric Pathways: Non-Equilibrium Thermodynamics Meet Psychology

In humans, age-associated degrading changes, widely observed in molecular and cellular processes underly the time-dependent decline in spatial navigation, time perception, cognitive and psychological abilities, and memory. Cross-talk of biological, cognitive, and psychological clocks provides an integrative contribution to healthy and advanced aging. At the molecular level, genome, proteome, and lipidome instability are widely recognized as the primary causal factors in aging. We narrow attention to the roles of protein aging linked to prevalent amino acids chirality, enzymatic and spontaneous (non-enzymatic) post-translational modifications (PTMs ^SP), and non-equilibrium phase transitions. The homochirality of protein synthesis, resulting in the steady-state non-equilibrium condition of protein structure, makes them prone to multiple types of enzymatic and spontaneous PTMs, including racemization and isomerization. Spontaneous racemization leads to the loss of the balanced prevalent chirality. Advanced biological aging related to irreversible PTMs ^SP has been associated with the nontrivial interplay between somatic (molecular aging) and mental (psychological aging) health conditions. Through stress response systems (SRS), the environmental and psychological stressors contribute to the age-associated “collapse” of protein homochirality. The role of prevalent protein chirality and entropy of protein folding in biological aging is mainly overlooked. In a more generalized context, the time-dependent shift from enzymatic to the non-enzymatic transformation of biochirality might represent an important and yet underappreciated hallmark of aging. We provide the experimental arguments in support of the racemization theory of aging.     

配置受压钢筋满足柱轴压比要求的探讨

针对设计中常遇到的柱轴压比不足的问题进行了分析,提出并阐述了一种在柱中配置受压钢筋是解决柱轴压比不足的有效方法.     

氧气顶吹转炉冶炼初期二次燃烧流场速度分布规律

采用先进的速度测试手段(PIV)测量了氧气顶吹转炉初期冷态二次燃烧二维流场,发现了在氧射流两侧形成两个强回流区.分析了不同截面上二次氧射流速度的分布特点及射流两侧回流区的速度分布规律.     

Impact of dietary fibers on the properties and proteolytic digestibility of lactoferrin nano-particles

The application and development of biopolymer-based particulate delivery systems is receiving considerable attention from scientists and manufacturers seeking to engineer healthier and safer foods. Present work focused on the fabrication and proteolysis of bovine lactoferrin nano-particles onto which pectins, alginate and carrageenan were electrostatically deposited. DLS, CD and AFM were used to ascertain the formation of spherical structures with varying zeta potentials and modified protein folding. SDS-PAGE analyses of samples collected during simulated human gastro-duodenal digestion revealed that in the case of high and low methoxy pectin particle zeta potential values (−35.4 mV and −50.3 mV respectively) were found to be inversely linked to lactoferrin digestion rate. Moreover, the electrostatic binding of food grade iota-carrageenan onto lactoferrin nano-particles was found to yield highly charged particles (zeta = −69.2 mV) with low surface roughness and to enable a proportion of the lactoferrin to resist 1 h of simulated gastric digestion. Overall, these findings suggest that electrostatic biopolymer interactions may modulate protein digestion and possibly facilitate controlled protein delivery to the upper gastrointestinal tract or have implications to protein nutritional value.     

支撑L吊墙大横梁立柱的设计计算

以某大型浮法玻璃熔窑支撑L形吊墙大横梁的立柱为例,介绍了偏心受压立柱的设计计算方法。