THz-TDS signal analysis and substance identification via the conformal split

A terahertz time-domain spectroscopy(THz-TDS)imaging system can obtain high-dimensional signals with substance fingerprint information.By introducing geometric algebra,a novel signal analysis approach to THz-TDS signals is developed based on an optical physical mechanism.Using this approach,signals are represented with vectors in the high-dimensional real vector space.Geometric distribution properties and algebraic relationships of THz-TDS signals are deduced.It is proved that every complex refractive index of substances relates to a unique 2-blade,the vectors corresponding to the samples of the same substance are collinear and belong to the intrinsic 2-blade of the substance.When decomposed through the conformal split with respect to a 2-blade,THz-TDS signals of high dimensionality can be related to vectors in a 2-dimensional subspace.Based on the conformal split properties we deduced,two criteria for substance identification on the basis of THz-TDS signals are proposed.Accordingly,a novel substance identification method via the conformal split is presented.In the method,the 2-blade related to each "known" substance is calculated with two vectors corresponding to THz-TDS signals measured from samples of the substance but with dierent thicknesses.Using the conformal split with respect to those 2-blades,an identified vector corresponding to a THz-TDS signal is linearly related to the vector in a 2-dimensional subspace.The substance of a sample can be identified using criteria on the projected vectors in the subspaces.This method can contribute to accurate classification and identification.Finally,two experiments are presented that show the feasibility and accuracy of this method.     

Poly(chitosan-ester-ether-urethane) Hydrogels as Highly Controlled Genistein Release Systems

Polymeric hydrogels play an increasingly important role in medicine, pharmacy and cosmetology. They appear to be one of the most promising groups of biomaterials due to their favorable physicochemical properties and biocompatibility. The objective of the presented study was to synthesize new poly(chitosan-ester-ether-urethane) hydrogels and to study the kinetic release of genistein (GEN) from these biomaterials. In view of the above, six non-toxic hydrogels were synthesized via the Ring-Opening Polymerization (ROP) and polyaddition processes. The poly(ester-ether) components of the hydrogels have been produced in the presence of the enzyme as a biocatalyst. In some cases, the in vitro release rate of GEN from the obtained hydrogels was characterized by near-zero-order kinetics, without “burst release” and with non-Fickian transport. It is important to note that developed hydrogels have been shown to possess the desired safety profile due to lack of cytotoxicity to skin cells (keratinocytes and fibroblasts). Taking into account the non-toxicity of hydrogels and the relatively highly controlled release profile of GEN, these results may provide fresh insight into polymeric hydrogels as an effective dermatological and/or cosmetological tool.     

磷酸西格列汀制剂中有关物质的合成

摘要：以西格列汀为原料依次富马酸二甲酯和马来酸酐分别经氮杂迈克尔加成和胺化反应制备相应西格列汀有关物质：①以西格列汀和富马酸二甲酯为原料，在DBU催化剂作用下，在N2保护下25℃搅拌6小时，经氢氧化锂，用乙酸乙酯-盐酸调节pH后，水相析晶体系分离提纯，得到西格列汀加合物有关物质I，HPLC纯度大于99%，收率76%；②以马来酸酐为原料，在K2CO3催化作用下，室温搅拌2小时，经一步法胺解开环反应制备西格列汀有关物质II，收率97%。本方法路线短，能耗低，生产成本低，操作简单，两种西格列汀有关物质收率好纯度高，适合工业化生产。     

湖北省高技术产业发展与产业升级的关联分析

从规模、利润、行业构成和技术创新能力4个方面,分析了湖北省高技术产业的现状,运用灰色关联模型,计算出湖北省高技术产业发展与产业升级之间的灰色关联系数,在系统分析湖北省高技术产业发展与产业升级之间的关联效应的基础上,提出了湖北省产业升级的相关建议。     

基于混合模型的舰船腐蚀相关静态电、磁场

为研究舰船水下腐蚀相关静态电场、磁场的分布特征,提出了以舰船水下标量电位为线索,对舰船进行混合建模,即将舰船等效为水平电流线和离散三分量电偶极子的组合,通过测量舰船下方某平面上的标量电位分布,对混合模型中的未知结构参量进行拟合,以建好的混合模型为基础对舰船水下腐蚀相关静态电、磁场进行研究.在实验室中模拟海洋环境,利用1∶100船模对建模方法进行了验证,并以建好的混合模型为基础,计算了船模水下腐蚀相关静态电、磁场的分布特征.实验结果表明混合模型结构简洁、实测数据量小、建模计算量小、模型稳定,比较适合用于舰船腐蚀相关静态电、磁场分布特点的研究.     

多次采样m序列法辨识LTI脉冲响应计算方法

研究一个时钟周期内多次采样条件下m序列法辨识线性时不变系统脉冲响应的计算方法,推导出脉冲响应序列与m序列周期、幅度及采样率之间的关系表达式。将双极性m序列信号的自相关特性进行均匀抽样,写成全周期内的统一表达式,代入维纳-何甫方程,再利用循环右移矩阵将脉冲响应用输入、输出采样序列表达出来。在matlab平台上对算法进行仿真实验,结果证明这种算法是正确的。     

Support principles of NPR bolt/cable and control techniques of large-deformation disasters

Deep mining has been paid much more attention because of the depletion of shallow mining resources.Traditional bolts could be invalid to accommodate large displacement and deformation in geomaterials.Consequently, alternative support and reinforcement bolts need to be studied and their constitutive models also need to be developed to help understanding for the complex stress-strain responses of rock masses under loadings. The effect of Negative Poisson's Ratio(NPR) that is attributed to the swelling phenomenon along the lateral direction may appear in metal materials under tensional loadings. Thence NPR materials often have an advantage over NPR ones in mechanical behavior such as impact resistance, antishearing, and energy absorbed. From the characteristics of NPR materials, a series of bolt and cable supports with the effect of NPR and constant-resistance have been recently developed. We here firstly introduce the structural features of NPR support. Then the constitutive model of NPR support is presented and its corresponding equation of energy equilibrium. Its basic principle interacted on rock masses is further discussed. Finally, NPR cables are employed to support the slope of an open-pit mine. The applications show that NPR cables can ease failure within the slope and play an important role in predicting and providing early warning of slope failure, together with a monitoring system of slope stability.     

市场机制下建筑节能相关利益主体博弈研究

充分发挥市场机制对节能产品的调控作用是市场经济的基本内容。通过对建筑节能市场发展中存在的相关问题研究,发现我国建筑节能市场的外部性和信息不对称性是产生问题的根源。全面分析建筑节能市场中政府、开发商、消费者以及其他服务组织等利益主体对市场培育的核心作用,通过构建政府与开发商、开发商与消费者之间的动态博弈模型,研究相关利益主体进一步完善建筑节能市场应采取的对策。     

中国古代几种含氮物质的热处理渗入效果初探

根据文献记载，我国古代有采用含氮物质进行热处理事实，分析了古代渗氮处理的可能性和前提条件，具体实践了几种文献记载含氮物质的渗氮处理。试验结果表明，Lu硝容易升华，基本没有渗氮效果，但可能起到一定催渗作用；硝单独使用渗氮效果也不明显；牛角灰、毛发灰、箬皮灰都有明显的渗氮作用；加硝有促进作用，硝与毛发灰共同作用有显著渗氮效果，并获得了较好的含氮化合物渗层。     

浅议网络体系结构与相关技术研究

随着高新科学技术的发展,互联网的规模也不断扩大.人们对互联网需求也越来越多,而现有的网络体系结构开始难以满足人们的需求.本文主要通过讨论现今网络体系结构存在的问题,对相关技术进行研究.