高效辐射换热器的研制

本文所介绍的高效辐射换热器是指在其环缝通道中安装有网状二次传热面的辐射换热器，用对比实验方法研究了它们在空气预热温度、给热系数和阻力系数上的差别．实验表明：高效辐射换热器可强化空气侧的传热，其综合传热系数达５９Ｗ／（ｍ２·℃），而阻力系数可控制在３０００Ｐａ以内．     

基于全信息新陈代谢的GM（1，1）电力预测

传统的灰色预测模型所需的样本容量较少,仅4个数据就可以建立灰色预测模型。虽然传统的灰预测建模较为简单,但是忽略了对预测较为确利的新信息,容易产生预测模型老化的现象,预测精度不高。全信息新陈代谢的GM（1,1）灰色预测模型更为合理、科学,全信息建模避免了局部信息建模的局限性,每预测一个结果去除原始数列的最老数据的新陈代谢处理保证了预测数列的实效性,并用Matlab实现改进GM（1,1）模型的编程计算,应用于双流县电力需求量的预测,预测精度好。     

Mine,ours, and yours: Whose engagement and prior knowledge affects individual achievement from online collaborative learning?

In computer-supported collaborative learning research, studies examining the combined effects of individual level, group level and within-group differences level measures on individual achievement are scarce. The current study addressed this by examining whether individual, group and within-group differences regarding engagement and prior knowledge predict individual achievement. Engagement was operationalised as group members' exhibited activities in the task space (i.e., discussing domain-content) and social space (i.e., regulating ideas, actions and socioemotional processes). Prior knowledge and achievement were operationalised as group members' performance on a domain-related pre-test and post-test, respectively. Data was collected for 95 triads of secondary education students collaborating on a complex business-economics problem. Subsequently, three different multilevel models were tested to examine the combined effect. First a model with the individual level measures (model 1) was tested and in subsequent models the group level measures (model 2) and within-group levels measures (model 3) were added. Findings indicate model 2 showed the best fit; group members' individual engagement in the social space activities as well as the groups' average prior knowledge positively predicts individual achievement. No effects were found for either group members' or groups' engagement in the task space and for the within-group differences.     

Inquiry-based mobile learning in secondary school science education: A systematic review

Recent years have seen a growing call for inquiry-based learning in science education, and mobile technologies are perceived as increasingly valuable tools to support this approach. However, there is a lack of understanding of mobile technology-supported inquiry-based learning (mIBL) in secondary science education. More evidence-based, nuanced insights are needed into how using mobile technologies might facilitate students' engagement with various levels of inquiry and enhance their science learning. We, therefore, conducted a robust systematic literature review (SLR) of the research articles on mIBL in secondary school science education that have been published from 2000 to 2019. We reviewed and analysed 31 empirical studies (34 articles) to explore the types of mIBL, and the benefits and constraints of mIBL in secondary school science education. The findings of this SLR suggest new research areas for further exploration and provide implications for science teachers' selection, use and design of mIBL approaches in their teaching.     

合金工具钢二次硬化能力的判别

为寻求在钢的成份和二次硬化能力之间的定量关系,对国内外40多种钢按作者提出的合金化参数进行计算和整理,证明了用“平衡碳”(Cp)和“碳饱和度”(A) 两个合金化参数判别 (预报) 钢的二次硬度的可能性。     

双参数Bézier曲线的升二次扩展

本文以二次Bernstein基函数为例,首次提出了含双参数基函数的新扩展——αβQ—Bern-stein基函数,此类基函数具有新的特点,即基函数的扩展次数一次性升高两次,且包含了二次多项式和带一个参数的三次多项式基函数的所有性质。基于这组基函数定义了αβQ—Bézier曲线,该曲线也含有参数,具有形状可调性,当α与β取某些值时曲线能达到C4连续或在某个端点处C0连续。最后与含两个参数的升一次Bézier曲线进行比较,该曲线具有调节范围广、灵活性更强的优势。     

流水线上机械手克隆转换开关改性塑料的选择

转换开关是用在工业生产自动流水线机械手中一种易磨损和大量消耗的塑料制品,以前依靠外国进口,花费了大量外汇。由于转换开关的精度极高,甚至超过金属件的制造精度。故不仅要求制品在成型加工过程中不能有微小的变形,甚至需要严格控制塑料的收缩量。使得所有成型孔的精度达到IT6级以上,平面度不大于0.02 mm,圆柱度不大于0.01 mm。通过对亚光微珠增强聚碳酸脂改性材料的选择,实现控制了制品变形量和提高了耐磨性的目的,通过超高精度孔的二次限制工艺的实施,使得制品孔的精度可达到IT4级以上,圆柱度为0.002 mm以内。国产转换开关完全取代了进口产品,且其精度和寿命远高于进口产品,为超高精度注射件加工创出了一种新方法,也为有关单位节约了大量外汇。     

Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells

Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants produced by incomplete combustion of organic matter. They induce their own metabolism by upregulating xenobiotic-metabolizing enzymes such as cytochrome P450 monooxygenase 1A1 (CYP1A1) by activating the aryl hydrocarbon receptor (AHR). However, previous studies showed that individual PAHs may also interact with the constitutive androstane receptor (CAR). Here, we studied ten PAHs, different in carcinogenicity classification, for their potential to activate AHR- and CAR-dependent luciferase reporter genes in human liver cells. The majority of investigated PAHs activated AHR, while non-carcinogenic PAHs tended to activate CAR. We further characterized gene expression, protein abundancies and activities of the AHR targets CYP1A1 and 1A2, and the CAR target CYP2B6 in human HepaRG hepatoma cells. Enzyme induction patterns strongly resembled the profiles obtained at the receptor level, with AHR-activating PAHs inducing CYP1A1/1A2 and CAR-activating PAHs inducing CYP2B6. In summary, this study provides evidence that beside well-known activation of AHR, some PAHs also activate CAR, followed by subsequent expression of respective target genes. Furthermore, we found that an increased PAH ring number is associated with AHR activation as well as the induction of DNA double-strand breaks, whereas smaller PAHs activated CAR but showed no DNA-damaging potential.     

Energy Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy

With more than 25 million people affected, heart failure (HF) is a global threat. As energy production pathways are known to play a pivotal role in HF, we sought here to identify key metabolic changes in ischemic- and non-ischemic HF by using a multi-OMICS approach. Serum metabolites and mRNAseq and epigenetic DNA methylation profiles were analyzed from blood and left ventricular heart biopsy specimens of the same individuals. In total we collected serum from n = 82 patients with Dilated Cardiomyopathy (DCM) and n = 51 controls in the screening stage. We identified several metabolites involved in glycolysis and citric acid cycle to be elevated up to 5.7-fold in DCM (p = 1.7 × 10⁻⁶). Interestingly, cardiac mRNA and epigenetic changes of genes encoding rate-limiting enzymes of these pathways could also be found and validated in our second stage of metabolite assessment in n = 52 DCM, n = 39 ischemic HF and n = 57 controls. In conclusion, we identified a new set of metabolomic biomarkers for HF. We were able to identify underlying biological cascades that potentially represent suitable intervention targets.