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排序方式: 共有10000条查询结果,搜索用时 234 毫秒
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233.
XIAO Chang-jiang SUN Ming ZHOU Hong-yan LIU Sui-xin LONG Kai-chao HE Fei LI Tong 《中南工业大学学报(英文版)》2005,12(Z1)
Objective Study on the effect of NF-κB in ox-LDL injured HUVEC-304 and the intervention with the serum of Tongmai Decoction. Methods Tongmai Decoction herbage-contained serum was made by the serum pharmacology methods, then the HUVEC-304 cells were divided into 5 groups and incubated for 24 h: 1) normal group;2) fetal calf serum group; 3) ox-LDL group; 4) simvastatin group; 5) Tongmai Decoction group. RT-PCR was used to determine the mRNA of NF-κB in the cells, Western Blot Assay was used to determine the protein content of NF-κB in the cells. Results 1) Compared with the cells in normal group and serum control group , the endothelial cells in ox-LDL group are seriously injured, while those in Tongmai Decoction group grow better; 2) Compared with the cells in normal group and fetal calf serum group, the expressions of NF-κB gene and protein are up-regulated in ox-LDL group(P<0.05, P<0.01); 3) Compared with the cells in ox-LDL group, the expression of NF-κB gene and protein in Tongmai Decoction group are significantly down-regulated, there is no difference between Tongmai Decoction group and simvastatin group(P>0.05). Conclusion Tongmai Decoction can protect the injured endothelial cells, up-regulate the expressions of NF-κB gene and protein content. 相似文献
234.
林伟波 《水利水电科技进展》2006,26(2):59-61
以上海市淀北片河网闸门为例,开发了以基于Web的B/S结构为主、B/S与C/S相结合的河网闸门自动调度系统,介绍了该系统的整体框架和各子系统的功能。经实践检验,基于B/S与C/S相结合的闸门自动调度系统发挥了B/S与C/S各自的优点,提高了防洪决策的及时性和准确性。 相似文献
235.
氨氮监测采用预蒸馏处理后,比色测定结果明显偏低。在样品预蒸馏处理过程中,硼酸作为吸收液,使显色时溶液pH值偏低,导致显色不充分是其主要影响因素。通过采取增加显色剂加入量的方法,解决了显色pH值偏低的问题,得到满意的测定结果。 相似文献
236.
Yan Jianhui Zhang Houan Tang Siwen Li Yimin 《中国稀土学报(英文版)》2006,24(5):548-548
The oxidation behavior of 0. 8% La2O3- Mo5Si3/MoSi2 composites at 1200℃ in air was investigated. The results reveal that the oxidation resistance of the material with 0. 8% La2O3 and Mo5Si3 is impaired. The oxidation resistance is decreased with increasing Mo5Si3 content. The mass loss follows a linear law in the initial oxidation. With oxidation time prolonging, a continuous and dense oxidation scale prevents oxygen from diffusing increasing when and leads to mass change a Mo5Si3 content is less than 30%. However, the composite shows "PEST" with the addition of 40% Mo5Si3. With increasing Mo5Si3 content, the oxidation resistance of 0.8% La2O3- Mo5Si3/MoSi2 decreases. This attributes to the poor oxidation resistance of M05Si3 and the relative density decreasing of 0. 8% La2O3-Mo5Si3/MoSi2 composite. 相似文献
237.
Nie Xin-min Gui Rong Zhao Hong-shan Ma Da-long Li Deng-qing Yuan Hong Huang Zu-fa 《中南工业大学学报(英文版)》2005,12(1):310-312
Objective Tacrolimus is an immunosuppressive drug with narrow therapeutic range and wide interindividual variation in its pharmacokinetics.
Tacrolimus is a substrate of cytochrome P450(CYP)3A5. The aim of this study was to evaluate whether the A6986G polymorphism
is associated with tacrolimus concentration /dose ratio. Methods Fifty-two Chinese renal transplant patients were enrolled in this study. Their body weight, dosage and concentration of tacrolimus
were observed. CYP3A5 genotype was determined by polymerase chain reaction followed by restriction fragment length polymorphism
analysis. Results A significant association was found between tacrolimus levels per dose/kg/d and CYP3A5 gene A6986G polymorphism (P<0.001). The CYP3A5 * 3 * 3 patients have a significantly higher tacrolimus level/dose than CYP3A5 * 1 * 1 and CYP3A5 * 1
* 3. Conclusions CYP3A5 gene A6986G polymorphism is associated with tacrolimus pharmacokinetics and dose requirements. Pharmacogenetic methods
could be employed prospectively to help the dose selection and to individualize immunosuppressive therapy according to the
result.
Foundation item: Project (03GZ3072) supported by the Science and Technology Department of Hunan Province; project (2004035206) supported by
the China Postdoctoral Foundation and project (30300383) supported by the National Natural Sciences Foundation of China 相似文献
238.
孙耀华 《石油地球物理勘探》2003,38(1):17-21
地震勘探技术应用可以分为以二维地震研究构造为主的地震勘探初级阶段、以地震地层学为主的地震勘探中级阶段、以三维地震油藏静态描述为主的地震勘探高级阶段、以地震储层研究为主的开发地震妆级阶段和以四维地震进行油藏监测为主的开发地震高级阶段。针对5个不同阶段的地质条件和地质任务,选择使用合理的地震勘探技术是有效提高勘探开发效益的重要途径。焉耆盆地的勘探开发体现了以地震勘探为主的思路,在勘探开发过程中重视了针对不同勘探开发阶段和不同的地质 地震技术,因此,在早期勘探开发中取得了很好的经济效益。 相似文献
239.
Fabrication of multi-walled carbon nanotube reinforced polyelectrolyte hollow nanofibers by electrospinning 总被引:1,自引:0,他引:1
Hybrid hollow multi-walled carbon nanotubes (MWCNTs)/polyelectrolytes (PE) nanofibers were prepared by a combination of the electrospinning method and layer-by-layer (LbL) technique. The mixed polystyrene (PS)/MWCNTs nanofibers were obtained by electrospinning method, which were employed as templates to self-assembly multilayered polyelectrolytes by LbL technique. Hollow MWCNTs/PE nanofibers were obtained by selectively removed part of the template: PS, which is confirmed by Raman spectra, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). 相似文献
240.
用化学还原法合成了FeBP非晶态合金超细微粒,用电感耦合等离子体光谱(ICP)、X射线粉末衍射(XRD)、透射电子显微镜(TEM)和差热分析(DSC)等手段对其进行了物性表征,并用微型催化反应装置考察了其对PH3分解的催化作用,结果表明,非晶态合金FeBP对PH3的分解具有良好的催化作用,能使PH3的分解温度从800℃以上降到500℃左右。490℃时分解率超过90%,540℃时达100%。 相似文献