Augment low-field intra-operative MRI with preoperative MRI using a hybrid non-rigid registration method

Background

Preoperatively acquired diffusion tensor image (DTI) and blood oxygen level dependent (BOLD) have been proved to be effective in providing more anatomical and functional information; however, the brain deformation induced by brain shift and tumor resection severely impairs the correspondence between the image space and the patient space in image-guided neurosurgery.

Method

To address the brain deformation, we developed a hybrid non-rigid registration method to register high-field preoperative MRI with low-field intra-operative MRI in order to recover the deformation induced by brain shift and tumor resection. The registered DTI and BOLD are fused with low-field intra-operative MRI for image-guided neurosurgery.

Results

The proposed hybrid registration method was evaluated by comparing the landmarks predicted by the hybrid registration method with the landmarks identified in the low-field intra-operative MRI for 10 patients. The prediction error of the hybrid method is 1.92 ± 0.54 mm, and the compensation accuracy is 74.3 ± 5.0%. Compared to the landmarks far from the resection region, those near the resection region demonstrated a higher compensation accuracy (P-value = .003) although these landmarks had larger initial displacements.

Conclusions

The proposed hybrid registration method is able to bring preoperatively acquired BOLD and DTI into the operating room and compensate for the deformation to augment low-field intra-operative MRI with rich anatomical and functional information.     

基于Gabor多尺度空间的不变兴趣点检测

针对以往仿射不变兴趣点的特征尺度不能直接断定的问题, 提出一种基于Gabor多尺度空间的不变兴趣点检测算法。该算法主要包括三个步骤：应用Gabor滤波器组与图像卷积建立图像Gabor多尺度空间; 通过极大值准则检测兴趣点并直接断定特征尺度; 采用二阶矩矩阵描述兴趣点局部结构。实验结果表明, 相比较其他Hessian-Affine、MSER等算法, 该算法在图像模糊和JPEG压缩情况下可重复率和可匹配率均取得最好结果, 是一种能有效直接提取特征尺度的兴趣点检测算法。     

Transient and steady-state deformations and breakup of dispersed-phase droplets of immiscible polymer blends in steady shear flow

Transient and steady-state deformations and breakup of viscoelastic polystyrene droplets dispersed in viscoelastic high-density polyethylene matrices were observed in a simple steady shear flow between two transparent parallel disks. By separately varying the elasticities of the individual blend components, the matrix shear viscosity, and the viscosity ratio, their effects on the transient deformation, steady-state droplet size, and the breakup sequence were determined. After the startup of a steady shear flow, the viscoelastic droplet initially exhibits oscillations of its length in the flow direction, but eventually stretches preferentially in the vorticity direction. We find that at fixed capillary number, the oscillation amplitude decreases with increasing droplet elasticity, while the oscillation period depends primarily on, and increases with, the viscosity ratio. At steady-state, the droplet length along the vorticity direction increases with increasing capillary number, viscosity ratio, and droplet elasticity. Remarkably, at a viscosity ratio of unity, the droplets remain in a nearly undeformed state as the capillary number is varied between 2 and 8, apparently because under these conditions a tendency for the droplets to widen in the vorticity direction counteracts their tendency to stretch in the flow direction. When a critical capillary number, Ca_c, is exceeded, the droplet finally stretches in the vorticity direction and forms a string which becomes thinner and finally breaks up, provided that the droplet elasticity is sufficiently high. For a fixed matrix shear stress and droplet elasticity, the steady-state deformation along the vorticity direction and the critical capillary number for breakup both increase with increasing viscosity ratio.     

In situ visualization of drop deformation,erosion, and breakup in high viscosity ratio polymeric systems under high shearing stress conditions

In this paper, deformation and breakup under simple shear of single molten polymer drops in a polymer matrix were investigated. Flow visualization was carried out in a Couette‐Flow apparatus under relatively high shear rates and temperatures up to 230°C. Drop/Matrix combinations were composed of polystyrene drops of 0.5–0.6 mm in diameter in polyethylene matrix, and ethylene–propylene copolymer drops of approximately the same size in polypropylene matrix. The deformation and breakup processes were studied under steady state and time‐dependent shearing conditions. Either for steady state or time‐dependant shearing conditions, drop elasticity generated at relatively high shear rates helped the drops to align perpendicular to the flow direction, i.e., parallel to vorticity axis. Also, the most striking non‐Newtonian effects for the high viscosity ratio systems were the surface erosion and the drop splitting mechanisms. The particles eroded off the main droplet surface were very fine, in the range of 10–50 μm, and led to a significant reduction in main drop size before its final breakup. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 2582–2591, 2006     

基于GM（1，1）和线性回归模型在印刷包衬压缩变形中的数据预测研究

运用线性回归对预测数据进行分析,剔除异常数据,用GM（1,1）模型进行预测,有效降低了数据相对误差,提高了预测数据的精度。选用印刷包衬压缩变形的压缩变形量值,用线性回归进行数据分析并剔除异常数据后用GM（1,1）进行预测,使得预测数据具有更高的准确性和适应性。实验及仿真结果表明,经过前期数据分析整理后的灰色预测模型,其预测期望值远优于单纯的回归模型和GM（1,1）模型。     

分离机转鼓超速自增强的变形分析

本文采用弹塑性有限元法和解析法,对分离机转鼓的主要零件进行了超速自增强的变形分析。认为,用奥氏体不锈钢等低强度钢制造的转鼓零件应按塑性准则进行强度与变形分析。提出了以某特征位置处的残余变形作为超速的控制参量。理论计算与分析表明,对用本构关系符合Ramberg—Osgood关系的奥氏体不锈钢制造的转鼓零件,超速后的残余变形具有下列规律:u~r=R[Aφ~a-B],该式可以作为起速设计的计算依据,并应用于超速工艺中。     

基于重标极差法和神经网络的隧道变形趋势判断

为准确、科学及全面地对隧道变形进行趋势判断和预测分析,将隧道的变形过程划分为中期阶段和长期阶段,利用R/S分析对其位移序列和速率序列进行趋势判断研究,再利用PSO-BP神经网络对各阶段的变形进行预测,将预测结果与R/S分析结果进行对比,验证两者的一致性。利用两个工程实例进行检验,得出各序列的Hurst指数均大于0.5,说明各序列均具有持续变形的长期性,且位移序列的趋势性均大于速率序列的趋势性;同时,变形预测结果也显示隧道后期变形将持续增加,验证了R/S分析的准确性。     

地铁深基坑分区开挖监测及数值模拟

对于狭长的地铁车站深基坑,围护结构区域内岩土体在实际施工时经常采用分区的方式进行开挖。为了分析分区开挖工况下深基坑的稳定性规律,选取合肥市某地铁车站深基坑作为研究对象,运用有限差分软件对实际工程进行数值模拟。比较模型计算结果与现场实测结果,得到了基坑分区开挖过程中围护结构侧向位移、横向支撑轴力,以及地表沉降的变化规律。研究结果表明:现场实测结果与数值模拟结果较为接近且均小于规范限值,数值模型能较好地反映基坑变形特性;随着开挖的进行,围护结构变形出现明显的"鼓肚"状,最大侧向位移点向基坑中段移动;支撑轴力前期发展较快,之后趋于平稳;邻近地表沉降呈现为凹槽状,基坑开挖影响范围约在40 m内。研究结果可为其他类似工程设计或施工决策提供参考。     

陶瓷坯体增强剂聚丙烯酸钠在艺术瓷成形过程的应用

本文合成了一系列不同相对分子质量的聚丙烯酸钠,应用于艺术瓷的坯体中,研究了聚丙烯酸钠对艺术瓷坯体强度、变形率的影响,并对聚丙烯酸钠增强机理进行了探讨。结果表明:聚丙烯酸钠可有效地提高艺术瓷坯体的成形强度,减少了坯体的变形率,当增强剂c加入的质量分数为0.6%时,坯体的干燥强度增加率达167.5%,坯体的变形率从50%降低到10%。