塑料袋冲缺口装置

本文着重论述塑料袋冲缺口装置机械部分设计原理、结构、特点及安全性。     

Increased Chondrocyte Apoptosis Is Associated with Progression of Osteoarthritis in Spontaneous Guinea Pig Models of the Disease

Osteoarthritis (OA) is the most common joint disease characterised by degradation of articular cartilage and bone remodelling. For almost a decade chondrocyte apoptosis has been investigated as a possible mechanism of cartilage damage in OA, but its precise role in initiation and/or progression of OA remains to the determined. The aim of this study is to determine the role of chondrocyte apoptosis in spontaneous animal models of OA. Right tibias from six male Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs were collected at 10, 16, 24 and 30 weeks of age. Fresh-frozen sections of tibial epiphysis were microscopically scored for OA, and immunostained with caspase-3 and TUNEL for apoptotic chondrocytes. The DH strain had more pronounced cartilage damage than BS2, especially at 30 weeks. At this time point, the apoptotic chondrocytes were largely confined to the deep zone of articular cartilage (AC) with a greater percentage in the medial side of DH than BS2 (DH: 5.7%, 95% CI: 4.2–7.2), BS2: 4.8%, 95% CI: 3.8–5.8), p > 0.05). DH had a significant progression of chondrocyte death between 24 to 30 weeks during which time significant changes were observed in AC fibrillation, proteoglycan depletion and overall microscopic OA score. A strong correlation (p ≤ 0.01) was found between chondrocyte apoptosis and AC fibrillation (r = 0.3), cellularity (r = 0.4) and overall microscopic OA scores (r = 0.4). Overall, the rate of progression in OA and apoptosis over the study period was greater in the DH (versus BS2) and the medial AC (versus lateral). Chondrocyte apoptosis was higher at the later stage of OA development when the cartilage matrix was hypocellular and highly fibrillated, suggesting that chondrocyte apoptosis is a late event in OA.     

NUMERICAL SIMULATION OF LEVEE BREACH FLOWS UNDER COMPLEX BOUNDARY CONDITIONS

Levee or dam failure can cause a significant disaster in most cases. A good prediction of the flood process especially in a real complex terrain is necessary for working out emergency plans for levee or dam breaches. Numerical simulations of levee or dam breach flow were carried out often with constant flow parameters and in relatively simple channels rather than in natural rivers with complex boundaries. This article presents our dedicated studies on the 2-D numerical model of levee or dam breach hydraulics with finite difference schemes. The good performance of the model is demonstrated by comparisons with the theoretical solution of an idealized dam-break flow over a frictionless flat rectangular channel. The model is also validated through its stability and conservation properties. The model is applied to simulate the flood propagation under complex boundary conditions, and the unsteady flood process in a river and in the dry floodplain with a complex bed terrain simultaneously. Furthermore, with respect to engineering practice, the numerical solutions can give special guidance to the effects of parameters such as the flood depth at different sites and the inundated area at different time periods after the levee breach and the travel time of the flood waves, which may be very important for practicing engineers in an efficient flood management.     

Do promises matter? An exploration of the role of promises in psychological contract breach.

Promises are positioned centrally in the study of psychological contract breach and are argued to distinguish psychological contracts from related constructs, such as employee expectations. However, because the effects of promises and delivered inducements are confounded in most research, the role of promises in perceptions of, and reactions to, breach remains unclear. If promises are not an important determinant of employee perceptions, emotions, and behavioral intentions, this would suggest that the psychological contract breach construct might lack utility. To assess the unique role of promises, the authors manipulated promises and delivered inducements separately in hypothetical scenarios in Studies 1 (558 undergraduates) and 2 (441 employees), and they measured them separately (longitudinally) in Study 3 (383 employees). The authors’ results indicate that breach perceptions do not represent a discrepancy between what employees believe they were promised and were given. In fact, breach perceptions can exist in the absence of promises. Further, promises play a negligible role in predicting feelings of violation and behavioral intentions. Contrary to the extant literature, the authors’ findings suggest that promises may matter little; employees are concerned primarily with what the organization delivers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

浅析我国合同法中的预期违约制度

阐述了预期违约的含义和特征,分析比较了预期违约制度和《合同法》中相关制度的异同,阐释了在我国采用预期违约制度的作用和现实意义。     

眼震检测中眼动曲线拟合方法研究

眼震检测是判断眩晕的一种重要方法,获取瞳孔位置波动曲线是眼震检测的主要内容,为了建立眼震检测中瞳孔位置波动曲线数学模型,采用最小二乘拟合与傅立叶级数拟合两种方法进行数据处理.通过对比,用Matlab中的Cfiool工具箱对瞳孔位置曲线进行傅立叶级数拟合的效果更好.实验证明,方法对眼动曲线建立的数学模型,能准确反映出瞳孔位置的实时变化情况.拟合结果为眩晕判定提供了重要依据,对今后的眼震研究具有一定的指导意义.     

Effects of Dam Removal on Tule Fall Chinook salmon Spawning Habitat in the White Salmon River,Washington

Condit Dam is one of the largest hydroelectric dams ever removed in the USA. Breached in a single explosive event in October 2011, hundreds‐of‐thousands of cubic metres of sediment washed down the White Salmon River onto spawning grounds of a threatened species, Columbia River tule fall Chinook salmon Oncorhynchus tshawytscha. We investigated over a 3‐year period (2010–2012) how dam breaching affected channel morphology, river hydraulics, sediment composition and tule fall Chinook salmon (hereafter ‘tule salmon’) spawning habitat in the lower 1.7 km of the White Salmon River (project area). As expected, dam breaching dramatically affected channel morphology and spawning habitat due to a large load of sediment released from Northwestern Lake. Forty‐two per cent of the project area that was previously covered in water was converted into islands or new shoreline, while a large pool near the mouth filled with sediments and a delta formed at the mouth. A two‐dimensional hydrodynamic model revealed that pool area decreased 68.7% in the project area, while glides and riffles increased 659% and 530%, respectively. A spatially explicit habitat model found the mean probability of spawning habitat increased 46.2% after dam breaching due to an increase in glides and riffles. Shifting channels and bank instability continue to negatively affect some spawning habitat as sediments continue to wash downstream from former Northwestern Lake, but 300 m of new spawning habitat (river kilometre 0.6 to 0.9) that formed immediately post‐breach has persisted into 2015. Less than 10% of tule salmon have spawned upstream of the former dam site to date, but the run sizes appear healthy and stable. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.     

归责原则辨析

在论述归责原则的法律涵义的基础上 ,分析了过错责任原则及严格责任原则的利弊关系和归责原则的作用 ,以说明我国《合同法》中归责原则配置的合理性     

小型水库溃坝洪水演算探讨

本文简要介绍了现有溃坝洪水的计算方法,根据新疆奎屯河"87"溃坝性洪水演算实例.推荐了一种简单可靠的适合小型水库溃坝洪水计算的方法.     

Orthokeratology reshapes eyes to be less prolate and more symmetric

PurposeThis prospective study assessed the influence of wearing and then discontinuing orthokeratology (OK) lenses on retinal shape and peripheral refraction in myopic children.MethodsFifty-eight myopic children (age 8–12 years) were equally divided into an OK group and a single vision spectacles (SVS) group. After 12 months of OK, it was discontinued for 1 month. Peripheral eye length (PEL), relative peripheral refraction (RPR), and corneal parameters were measured in the right eye on the nasal and temporal retinal sides at baseline, 6 months, and 12 months (13 months in OK group) visits.ResultsIn the SVS group, faster elongation of the temporal side PEL made the eyes more asymmetric and prolate, developing a temporal pointed shape. In the OK group, the nasal retinal side PEL grew faster, the nasal RPR developed less hyperopic defocus, and the eye shape became more symmetric and less prolate. The central cornea became thinner and flattened, while the peripheral cornea became steeper. Changes in corneal thickness, relative peripheral corneal power, and K-values were no significant differences for the OK and SVS groups at 12 months.ConclusionsThe cornea reverted to be no difference with myopic children with SVS after 1 month discontinuation of OK. The retinal shape of SVS eyes became more asymmetric and prolate with myopia progression. OK remodelled retinal shape to be less asymmetric and less prolate.