有线无线组合通信的便携式哨兵报警对讲系统

针对哨兵离开哨位处置突发警情时哨兵与值班室的联系中断这一问题,采用以有线通信和无线通信组合的方式设计了便携式哨兵报警对讲系统,实现哨兵离开哨位时与值班室的语音对话,同时实现哨兵遇到紧急情况无法进行语音对话时的紧急报警以及当哨兵遭到袭击倒地的自动检测报警。     

Smart Injectable Hydrogels for Cancer Immunotherapy

Hydrogels, a class of materials with a 3D network structure, are widely used in various fields especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and controlled release of small molecular drugs, macromolecular therapeutics, and even cells. With the rapid development of cancer immunotherapy, such injectable hydrogels have attracted wide attention for local immunomodulation to boost systemic anticancer immune responses, realizing more effective immunotherapy at lower doses. The latest progresses in the development of various smart injectable hydrogels for cancer immunotherapy are summarized here. Although applied locally, such injectable hydrogels can activate systemic antitumor immune responses, safely and effectively inhibiting the tumor metastasis and recurrence. Moreover, it is discussed how injectable hydrogel‐based cancer immunotherapy would contribute to the development of next generation of cancer treatment together with their potential for clinical translation.     

Biodegradable Nanoscale Coordination Polymers for Targeted Tumor Combination Therapy with Oxidative Stress Amplification

Nowadays various inorganic nanoparticles that generate highly reactive hydroxyl radical ( · OH) on the basis of Fenton‐like catalytic activity of metal ions have been designed for chemodynamic therapy. However, the high level of adaptive antioxidants [glutathione (GSH)] in cancer cells could effectively consume · OH to compromise the treatment efficiency and biosafety of these inorganic nanoparticles, and this is a general concern in chemodynamic therapy. Herein, a new biodegradable nanoscale coordination polymer (NCP) is developed by integration of cisplatin prodrug (DSCP) and iron (III) ions through a reverse microemulsion method. The DSCP in the NCPs could react with GSH to release free cisplatin, while the iron (III) ions could be reduced by GSH into iron (II) to enable Fenton reaction, subsequently leading to amplified intracellular oxidative stress. After surface modification of polyethylene glycol (PEG) and cyclo[Arg‐Gly‐Asp‐D‐Phe‐Lys(mpa)] peptide (cRGD), Fe‐DSCP‐PEG‐cRGD shows an excellent targeting effect against α_vβ₃‐integrin overexpressed tumor cells. Furthermore, Fe‐DSCP‐PEG‐cRGD enables significant chemo and chemodynamic therapy with dramatically enhanced therapeutic efficiency in comparison to relative monotherapies. Importantly, Fe‐DSCP‐PEG‐cRGD could be efficiently cleared out from mice through feces and urine postinjection 7 days. The NCP presented in this work is simple and economical, which shows great biodegradability and biosafety for potential clinical translation.     

改进型粒子群算法解决多维背包问题

微粒群优化算法(PSO)是一种基于种群的随机优化技术.将EDA算法与PSO算法结合起来,形成一种新的改进的算法(EPSO).算法将全局统计信息和全局最优解运用于解空间搜索,以期能更有效解决组合优化问题,最后将EPSO算法用于解决多维背包问题并进行了对比仿真实验.实验结果表明,在解决多维背包问题上,EPSO优于传统的PSO算法以及多种启发式智能算法,与此同时,EPSO算法使用更少的参数,因此更容易实现,运行更加稳定,效果更好.     

一种全局优化的激光光斑亚像素定中算法

根据激光光斑特征提出其中心位置检测方法,该法先假定激光光斑中心位置,再利用假定激光光斑中心点的投影圆上等效光强原理对其进行重建,并将重建前后两者的光强差的绝对值之和作为评价假定点与真实光斑中心距离的指标,最后,根据所述指标最小化原则求取激光光斑中心位置。理论分析表明,对于标准高斯分布的激光光斑,所述评价指标与假定点及真实光斑中心间的距离成正比,在真实光斑中心处,其评价指标值为零。对于实际激光光斑,在其中心处所述评价指标的值接近于零,为提高其抗噪声干扰能力,采用距离加权法作为其改进的评价指标。对有噪声干扰的实例计算结果表明,该法中心定位达到亚像素精度优于0.1 pixels,不仅定中精度高,而且算法速度快、稳定性好、抗干扰能力强。     

获得一维光子晶体最大带隙的介质宽度精确组合

采用传输矩阵法对一维光子晶体的带隙结构进行了研究.当介质层的宽度发生改变时,带隙也随之相应地发生变化.数值分析结果表明:通过对介质层不同厚度的组合可获得连续且更大的带隙,运用此方法可在不改变光子晶体材料总体介质厚度的情况下获得理想的滤波效果.     

表面层型半导体陶瓷电容器

对表面层型半导体陶瓷电容器的基本结构原理、关键生产技术、关键设计参数、关键生产设备以及电容器规格和典型特性作了简要介绍。     

一种新的电子系统综合可靠性分配法

介绍了一种考虑单元任务时间差异的串联系统拓展比例组合可靠性分配法,并在此基础上,提出了一种基于AGREE法和拓展比例组合法的新的电子系统综合可靠性分配方法。该方法适用于系统研制中常见的,既包含已有研制经验的单机也包含新研单机的串联电子系统,结合了AGREE法适用性广和比例组合法参考已研设备实际可靠性特性均衡分配可靠性指标的特点。将该方法应用于某卫星电子系统,应用结果表明该方法可行、有效。     

IPTV双模机顶盒终端技术在三网合一领域的应用

IPTV双模机顶盒作为广电双向交互业务开展的用户终端设备,其同时具备DVB-C与IP两种接入系统的方式。主要由软件和硬件两部分组成,整个硬件系统以高性能专用SOC SMP8635L为核心,辅以外围辅助芯片和电路所构成;软件部分则由嵌入式浏览器构成。随着三网融合业务和微电子技术的发展,IPTV机顶盒产品会越来越成熟,功能越来越强大。     

基于PMSM调速的高精度跟踪系统设计研究

从跟踪系统定位的精确性、跟踪的平稳性需求出发,结合交流伺服电机优良的控制性能,详述了通过采用合理的ARM FPGA芯片组控制策略以及完备的伺服控制芯片IRMCK201完成PMSM调速系统精确控制的方法。该控制策略的使用,提高了系统整体运动性能,实现了硬件资源的最大化利用。同时为交流伺服电机的容量选取方法提供了具有可操作性的参考资料。