珠江三角洲典型区域土壤重金属污染探查研究

以珠江三角洲典型区域研究高强度经济开发下土壤环境中重金属污染的状况。测定了84份样品中铜、锌、镉、铬、铅的含量水平。土壤中镉、铬、铅、镍、铜、锌的含量分别在0.166～0.433mgkg-1、2.28～94.28mgkg-1、20.36～143.3mgkg-1、2.29～63.55mgkg-1、4.8～65.1mgkg-1、10.06～131mgkg-1之间。从分析结果可以看出,镍、铅等元素在有些地方普遍偏高,且有的极为明显,已高出背景值108.3mgkg-1。其他元素也存在不同水平的富集,普遍高出背景值。     

基于基频的朝鲜语方言辨识方法的研究

该文提出了一种基于基音频率特征的中国朝鲜族语言、韩国朝鲜语和朝鲜朝鲜语方言的自动辨识方法。首先,选择具有良好区分度的基频移位差分系数作为三个方言的特征参数;其次,设计和采用了分层支持向量机分类器,并进一步引入投票法确定最佳的分类结果。实验结果表明该文提取的特征参数具有良好的区分性和较强的稳定性,该文提出的方言辨识方法比传统的移位差分倒谱系数特征方法识别率高,可以有效解决朝鲜朝鲜语、韩国朝鲜语和中国朝鲜族语言的方言辨识问题。     

The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant

Recently, a recombinant SARS-CoV-2 lineage, XD, emerged that harbors a spike gene that is largely derived from the Omicron variant BA.1 in the genetic background of the Delta variant. This finding raised concerns that the recombinant virus might exhibit altered biological properties as compared to the parental viruses and might pose an elevated threat to human health. Here, using pseudotyped particles, we show that ACE2 binding and cell tropism of XD mimics that of BA.1. Further, XD and BA.1 displayed comparable sensitivity to neutralization by antibodies induced upon vaccination with BNT162b2/Comirnaty (BNT) or BNT vaccination followed by breakthrough infection. Our findings reveal important biological commonalities between XD and Omicron BA.1 host cell entry and its inhibition by antibodies.     

BIM技术在珠三角水资源配置工程中的集成应用

针对水利工程行业数字化、信息化、智慧化水平较低,生产管理手段较落后问题,基于珠江三角洲水资源配置工程探索研究施工阶段BIM技术的集成应用,以BIM技术为基础,结合其他数字化与信息技术,搭建基于BIM技术的多维度数据管理支撑平台,从态势分析与辅助决策(进度、质量、安全、资金)、基于BIM+GIS的专题应用(盾构机与TBM...     

支持What-if分析的OLAP系统研究

数据仓库和OLAP是决策支持系统的重要组成部分.What-if分析是基于历史数据,对假设场景进行分析的重要手段,它可以为决策者提供重要的预测信息,是一种非常重要的决策支持分析过程.文中分析了what-if分析的研究现状,从不同的角度对what-if分析进行了分类.将其分为基于规则的what-if分析、基于delta表的差分数据存储与合并机制的what-if分析和基于CUBE增量维护方法的what-if分析三类,分析了各种实现方法的优点以及适用范围.给出了基于内存数据库的delta表模式的what-if分析算法和一种新的CUBE维护算法.最后对基于what-if分析的OLAP系统的未来研究方向进行了展望.     

A 1.2-V, 84-dB \begin{document}$\Sigma\Delta$\end{document} ADM in 0.18-μm digital CMOS technology

A low power and low voltage \begin{document}$\Sigma\Delta$\end{document} analog-to-digital modulator is realized with digital CMOS technology, which is due to full compensated depletion mode capacitors. Compared with mixed signal technology, this type of modulator is more compatible for pure digital applications. A pseudo-two-stage class-AB OTA is used in switched-capacitor integrators for low voltage and low power. The modulator is realized in standard SMIC 0.18 μm 1P6M digital CMOS technology. Measured results show that with 1.2 V supply voltage and a 6 MHz sample clock, the dynamic range of the modulator is 84 dB and the total power dissipation is 2460 μW.     

北部湾盆地乌石凹陷东区流沙港组三段储层物性主控因素及分布规律

南海北部湾盆地乌石凹陷东区流沙港组三段扇三角洲储层砂体厚度大、岩性复杂、物性变化快、优质储层展布不清,制约了下一步的开发部署。利用分析化验、钻测井和测试资料,从沉积环境、成岩作用和构造三方面来探讨其对储层物性的控制作用。沉积环境中的泥质杂基含量和分选磨圆对物性影响较大;成岩作用中的压实作用和溶解作用决定了孔隙的后期演化;古构造和断裂系统控制了酸性流体运移方向和路径。靠近大断裂的扇三角洲外前缘近端的水下分流河道储层,由于杂基含量低,分选磨圆较好,溶解作用强,物性较好,产能较高,是研究区的优质储层。     

Pituitary Tumor-Transforming Gene 1/Delta like Non-Canonical Notch Ligand 1 Signaling in Chronic Liver Diseases

The management of chronic liver diseases (CLDs) remains a challenge, and identifying effective treatments is a major unmet medical need. In the current review we focus on the pituitary tumor transforming gene (PTTG1)/delta like non-canonical notch ligand 1 (DLK1) axis as a potential therapeutic target to attenuate the progression of these pathological conditions. PTTG1 is a proto-oncogene involved in proliferation and metabolism. PTTG1 expression has been related to inflammation, angiogenesis, and fibrogenesis in cancer and experimental fibrosis. On the other hand, DLK1 has been identified as one of the most abundantly expressed PTTG1 targets in adipose tissue and has shown to contribute to hepatic fibrosis by promoting the activation of hepatic stellate cells. Here, we extensively analyze the increasing amount of information pointing to the PTTG1/DLK1 signaling pathway as an important player in the regulation of these disturbances. These data prompted us to hypothesize that activation of the PTTG1/DLK1 axis is a key factor upregulating the tissue remodeling mechanisms characteristic of CLDs. Therefore, disruption of this signaling pathway could be useful in the therapeutic management of CLDs.     

Delta算子不确定系统的区域极点约束保性能控制

研究了Delta算子描述下的具有范数有界参数不确定线性系统的圆形区域极点配置的保性能控制问题。运用线性矩阵不等式(LMI),把Delta算子闭环极点配置在D区域内,证明了保性能控制律存在的充要条件,并通过建立和求解一个凸优化问题,给出了具有极点约束的保性能控制设计。仿真例子验证了方法的可行性。     

新型“双重Δ调制”跟踪控制方法研究

提出了一种基于幅值△调制和时间△调制相结合的"双重△调制"电流跟踪控制新方法.将单边滞环电流比较器和开关周期定时器相结合,通过设定滞环比较器的下限值决定实际输出电流的下限,由定时器的定时周期决定实际输出电流的上限,该方法只需一个无滞环单阈值比较器,因而电路简单、动态响应快,特别是时间量化的载波定时保证了开关频率固定不变.给出了避免跟踪失步的一般性条件.仿真和实验结果均证明了该方法的有效性.