基于需求响应的虚拟电厂多时间尺度优化调度

随着我国不断加快新型电力系统建设,风电、光伏等越来越多的分布式资源大规模并网,但其随机性、波动性及分散性的特点给电力系统带来了多重不确定性。提出了一种考虑价格型需求响应的虚拟电厂多时间尺度优化调度方法,在日内调度模型中引入用户价格型需求响应,对用户负荷进行精准调控;采用基于蒙特卡罗与曼哈顿概率距离的场景生成与削减法处理风光出力、电价不确定性,减少日前日内出力偏差,再结合日前调度构成了多时间尺度优化调度模型,并采用滚动优化得到日内优化调度结果。以湖南某小型虚拟电厂系统进行算例仿真,结果表明,所提多时间尺度优化调度策略能够精确预测风光出力及用户负荷,在有效抑制功率波动的同时保证了系统的经济性。     

基于矩阵束方法的传输线系统瞬态响应分析

带有频变负载的传输线系统的瞬态响应分析是电磁兼容领域的一个重要内容,特别是对于频变负载网络较为复杂或内部结构不清晰的情况,其瞬态响应的分析较为困难。本文首先在采样频率点处对频变负载端口导纳进行测量或计算得到相应的采样导纳,并采用有理函数逼近的方式对端口导纳进行等效;之后采用矩阵束(MPM)方法求解出有理逼近函数所需的极点和留数,并将其代入到分段线性递归卷积(PLRC)技术中,实现传输线和频变负载连接点处电压的分段线性递归卷积表达;最后,结合传输线方程实现带有频变负载的传输线系统的瞬态响应分析,并通过2个算例对所提方法的性能进行验证。结果表明,所提方法在计算精确度上具有明显的优势。     

基于响应曲面法的超临界CO2萃取油基钻屑油相工艺优化

目的对超临界CO₂萃取油基钻屑中油相工艺参数进行优化。 方法采用响应曲面法对影响超临界CO₂萃取工艺的重要参数进行具体实验并根据实验结果进行数值模拟,通过模拟得出萃取时间、压力、温度和超临界CO₂流量等参数的优化数据。 结果响应曲面分析了各变量之间对萃取效果的影响,基于萃取数据建立了二次多项式模型,能够较好地拟合实验结果,得出最佳萃取条件为萃取压力25 MPa、温度323.15 K、时间90 min和流量25.0 L/h。 结论通过具体实验数据结合响应曲面法得出了最佳萃取条件,在该条件下油类最大去除率为95.22%。利用气相色谱仪-质谱联用仪(GC-MS)分析萃取物前后性状未发生明显变化,该方法能够更好地实现固液分离和资源回收。      

Sogatella furcifera Saliva Mucin-like Protein Is Required for Feeding and Induces Rice Defences

The white-backed planthopper (WBPH), Sogatella furcifera, is one of the most important piercing-sucking pests of rice (Oryza sativa) in Asia. Mucin-like salivary protein (SFMLP) is highly expressed in the salivary glands of WBPH, which plays an important role in WBPH feeding. In this study, WBPH injected with dsSFMLP had difficulty in sucking phloem sap from rice plants, which significantly reduced their food intake, weight, and survival. In contrast, the knockdown of the SFMLP gene had only a marginal effect on the survival of WBPH fed an artificial diet. Further studies showed that silencing SFMLP resulted in the short and single-branched salivary sheaths secretion and less formation of salivary flanges in rice. These data suggest that SFMLP is involved in the formation of the salivary sheath and is essential for feeding in WBPH. Overexpression of the SFMLP gene in rice plants promoted the feeding of WBPH, whereas silencing the gene in rice plants significantly decreased WBPH performance. Additionally, it was found that overexpression of SFMLP in rice plants elicited the signalling pathway of SA (salicylic acid) while suppressing JA (jasmonic acid); in contrast, silencing of the SFMLP gene in rice plants showed the opposite results. This study clarified the function of SFMLP in WBPH feeding as well as mediating rice defences.     

美国城市公共安全应急体系建设方法研究

全面紧急事态管理是美国公共安全管理中最基本的原则,包括全危险方法、综合紧急事态管理系统、紧急事态管理的生命周期、对各级政府及组织紧急救援资源的统一调配.美国国土安全部确定了了解、防止、保护、应对、恢复、服务和组织品质七大安全战略目标.美国联邦紧急事务管理局除制订全国防灾计划外,还制订可持续减灾计划和应急反应计划.社区应急反应小组是美国重要的市民组织队伍.     

Development of a Multi-Epitope Vaccine for Mycoplasma hyopneumoniae and Evaluation of Its Immune Responses in Mice and Piglets

Mycoplasma hyopneumoniae (Mhp), the primary pathogen causing Mycoplasma pneumonia of swine (MPS), brings massive economic losses worldwide. Genomic variability and post-translational protein modification can enhance the immune evasion of Mhp, which makes MPS prone to recurrent outbreaks on farms, even with vaccination or other treatments. The reverse vaccinology pipeline has been developed as an attractive potential method for vaccine development due to its high efficiency and applicability. In this study, a multi-epitope vaccine for Mhp was developed, and its immune responses were evaluated in mice and piglets. Genomic core proteins of Mhp were retrieved through pan-genome analysis, and four immunodominant antigens were screened by host homologous protein removal, membrane protein screening, and virulence factor identification. One immunodominant antigen, {"type":"entrez-protein","attrs":{"text":"AAV27984.1","term_id":"53987783","term_text":"AAV27984.1"}}AAV27984.1 (membrane nuclease), was expressed by E. coli and named rMhp597. For epitope prioritization, 35 B-cell-derived epitopes were identified from the four immunodominant antigens, and 10 MHC-I and 6 MHC-II binding epitopes were further identified. The MHC-I/II binding epitopes were merged and combined to produce recombinant proteins MhpMEV and MhpMEVC6His, which were used for animal immunization and structural analysis, respectively. Immunization of mice and piglets demonstrated that MhpMEV could induce humoral and cellular immune responses. The mouse serum antibodies could detect all 11 synthetic epitopes, and the piglet antiserum suppressed the nuclease activity of rMhp597. Moreover, piglet serum antibodies could also detect cultured Mhp strain 168. In summary, this study provides immunoassay results for a multi-epitope vaccine derived from the reverse vaccinology pipeline, and offers an alternative vaccine for MPS.     

一种新的TOC含量拟合方法研究与应用

由于取样的限制,通常在烃源岩评价中往往只能获得十分有限的实测烃源岩的TOC含量数据。但随着我国多数盆地精细勘探的深入,需要更加精细的烃源岩评价,因此,人们对测井数据拟合烃源岩的TOC含量变化越来越重视。目前该技术最先进的是人工神经网络拟合方法,但多种神经网络在拟合高成熟度碳酸盐岩烃源岩地层的TOC含量时相关性均不够高。针对研究区内烃源岩的特点,尝试了一种用图版分类-模糊排队-BP神经网络联合拟合TOC含量的新方法。利用该方法对鄂尔多斯盆地马家沟组的测井资料和实测总有机碳资料进行数据处理,将结果与ΔlogR方法、模糊神经网络方法的结果相比较,证实该方法的结果与实测值有更好的相关性,为系统了解鄂尔多斯盆地下古生界烃源岩发育提供了一定的科学依据。     

Acanthopanax senticosus Polysaccharide Enhances the Pathogen Resistance of Radiation-Damaged Caenorhabditis elegans through Intestinal p38 MAPK-SKN-1/ATF-7 Pathway and Stress Response

With the advancement of science and technology, humans are chronically exposed to ionizing radiation. It is crucial to look for efficient and low-toxic anti-radiation agents. Through preliminary screening, we found that Acanthopanax senticosus polysaccharide (ASPS) played a major role in regulating immune damage caused by radiation. The objective of this study was to apply the Caenorhabditis elegans—P. aeruginosa (PA14) infection model to illuminate the mechanism of ASPS increasing the pathogen resistance of radiation-damaged nematodes. Results indicated that ASPS (1 mg/mL) significantly enhanced the pathogen resistance of radiation-damaged nematodes by directly elevating the immune response of nematodes rather than by affecting the bacterial activity. Through further research on the p38 MAPK signaling pathway and related mutants, we found that ASPS functioned by the p38 MAPK pathway in the intestine, and SKN-1, ATF-7 as the downstream targets of PMK-1 participated the regulation of ASPS. In addition, ASPS markedly alleviated the stress status of damaged nematodes by regulating oxidative stress. Collectively, our findings suggest that ASPS enhances the pathogen resistance of radiation-damaged nematodes through the intestinal p38MAPK-SKN-1/ATF-7 pathway and stress response.