Drug Onset Cues, Conditioned Withdrawal, and Drug Relapse: Comment on McDonald and Siegel (2004).

Previous research has shown that under certain conditions environmental cues associated with morphine administration induce drug-opposite conditioned effects that mimic symptoms of opiate withdrawal. R. V. McDonald and S. Siegel (see record 2004-10475-001) extend these observations by demonstrating that acute exposure to a low dose of morphine induces symptoms of opiate withdrawal in rats previously exposed to a high dose of morphine. They hypothesized that early drug onset cues, repeatedly paired with later, larger drug effects, mediate the paradoxical effect of the low drug dose on behavior. They also hypothesized that conditioned withdrawal symptoms induced by the early drug onset cues may mediate the "priming" effect of drugs on relapse and craving. The authors of this comment discuss the degree to which the literature supports this hypothesis. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

底敞口充气浮箱研究和试验

提出底敞口充气浮箱的结构和概念。经模型模拟试验研究分析，经典浮力定律可用于这种浮箱的浮力计算；其动充气状况还具有一定的允许伤损面积。它的研究将为水陆两用车辆增大浮力，缩小外形，提高水上自下而上能力和潜驶潜伏提供具有诱惑力的工程应用前景。     

尾矿堆场对地下水及其水质影响的联合模拟研究

矿产资源开发利用后的废弃物堆场常处水文地质条件复杂、区域内外边界不规整的地带。为了客观评价堆场渗漏对地下水及其水质的影响,本文提出了适宜于复杂水文地质条件、复杂内外边界条件的地下水与地下水中污染物分布规律联合模拟分析的非构造网格FVM数值模型,通过在某化工行业尾矿堆场渗漏评价的具体应用,取得了很满意的结果。     

Optimal Locations of Groundwater Extractions in Coastal Aquifers

A regional water supply management model for coastal aquifers was developed. One of its outcomes is the definition of the optimized locations for groundwater withdrawal. Such a tool permits the analysis of alternative plans for groundwater extraction and the sustainable use of water resources in a coastal aquifer subject to saltwater intrusion. The principal components are the evolutionary optimization and the analytical/numerical simulation models. The optimization technique looks for the best well locations taking into consideration the economic results and the satisfaction of the societal water demand. However these two concerns are conditioned by trying to control the saltwater intrusion, i.e., preserving the environmental equilibrium. The simulation model uses the governing mathematical equations for groundwater movement to find the interface between freshwater and saltwater. Because of the non-linearity in the system and the possibility of a jumping interface, a security distance was defined. This is a controlling variable which can be set by the decision makers. The model was applied to a typical case with interesting results. For example, diagrams showing the relationship between the location of the wells and the security distance(s) are of importance to the managers. It was also crucial to have an understanding of the tradeoffs between groundwater withdrawals, positions of the wells from the coast line, and the security distance. The model was also applied to a real case in order to relate the extractions, distances and artificial recharge (not presented in this paper).     

Disentangling the Sources of Opioid Withdrawal Responses: Comment on McDonald and Siegel (2004).

R. V. McDonald and S. Siegel (see record 2004-10475-001) present new evidence for the idea that opioid drug-opposite responses can become conditioned to cues of initial drug onset and that they could, therefore, play a role in the development of tolerance of some drug effects and a role in the elicitation of withdrawal-like symptoms in cases in which addicted individuals are exposed to small doses of the drug they normally consume. In this comment, some puzzling features of the data are discussed, and alternative explanations are suggested. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

地下水污染修复的活性渗滤墙技术

活性渗滤墙是一种现场修复受污染地下水的新型技术，具有原理简单，施工方便，运行费用低廉等特点，活性渗滤墙垂直于地下水流动方向设置，当地下水流通过活性渗滤墙时，污染物与墙体材料发生化学反应，从而达到环境修复的目的。文中综述了活性渗滤墙技术的修复机理和实际应用，大量研究表明，应用金属铁作为活性渗滤墙材料，可以去除地下水中的重金属以及有机污染物，目前活性渗滤墙已经在世界各地应用，是一种非常有发展前景的环境污染修复技术。     

山前平原地下水侧向补给潜力空间变异模拟

SWAT模型利用分辨率较高的DEM数据,可以估算山前地下水侧向补给的空间变异,并可以计算不同降水年型下补给量的差别。模拟需要对研究区进行填洼、流向确定、汇流和河网水系的提取四步运算,并对河道临界支撑面积的取值进行分析。分别模拟了平水年和丰水年两种降雨年型下研究区13个出水口的地下水侧向补给潜力。在研究区,由于地形的变化,导致山与平原交接断面上出水口的集水面积变异非常大,因此山前平原所接受的地下水侧向补给量的空间变异也非常大。不同的降雨年型下,降雨量转化为地下水侧向补给量的比例也不同。平水年的转化比例较小,丰水年的转化比例较大。应用SWAT模型时,与ArcView的拓展模块有机结合,可以更方便提取完整的大流域,划分出合理的子流域。     

钢筋混凝土结构正截面强度计算理论的应用

简述了钢筋混凝土正截面强度计算理论的发展历程，介绍了其计算理论的特点及其存在的问题，并对今后需要进一步研究的问题进行了展望，为工程设计提供参考。     

φ140mm套管拔套侧钻工艺技术在濮城油田的应用

濮城油田开发后期,因事故导致损坏的井数不断增多,不仅损失了相当一部分储量,而且严重威胁着油田的发展。针对这一问题,应用拔套侧钻工艺技术对有潜能的事故井进行侧钻更新,投产后取得了良好的效果,成为油田增储上产和挖潜剩余油的重要手段,同时也为解决困扰油田发展的难题找到了好的方法。     

Smoking Withdrawal Dynamics: III. Correlates of Withdrawal Heterogeneity.

Five parameters of postcessation smoking withdrawal variability derived from clinical data (T. M. Piasecki, D. E. Jorenby, S. S. Smith, M. C. Fiore, & T. B. Baker, 2003a, 2003b) were predicted from baseline measures and pharmacotherapy assignment. Smokers who were more dependent, older, and high in negative affect reported more severe withdrawal. Women, heavier smokers, and those with a history of depression reported more variable symptoms. Smokers treated with nicotine patch, bupropion, or both reported less severe withdrawal than did those given placebo, but medication did not affect the slope of symptoms over time, day-to-day variability of symptoms, or the size of acute changes in symptoms associated with lapses to smoking. Prior research has shown that these symptom facets predict later relapse: thus, current pharmacotherapies may aid cessation by diminishing withdrawal severity, but they do not affect all clinically important aspects of withdrawal. (PsycINFO Database Record (c) 2010 APA, all rights reserved)