半刚性钢框架实用非线性分析

介绍了在钢框架分析中考虑连接柔性的方法以及常用的连接M–θr模型,建立了能够同时考虑几何、材料和连接非线性的精细塑性铰法三维梁柱单元。单元采用稳定函数考虑二阶效应和剪切变形,采用切线模量和抛物线函数考虑沿单元长度和截面的逐渐屈服,采用Kishi-Chen幂函数模型和修正梁单元方法模拟半刚性连接的非线性行为。利用ANSYS软件的用户可编程特性(UPFs)编写了单元程序,并将用户单元添加至ANSYS软件单元库中。半刚性框架算例分析表明:用户单元分析的荷载-位移曲线与试验结果吻合较好,与采用COMBIN 39单元模拟连接所分析的结果非常接近。     

多类混凝土和各向同性岩石损伤比强度准则

针对已有损伤比变量下的损伤比强度理论仅适用于混凝土且偏平面略有内凹等不足,基于多轴应力下混凝土损伤比强度理论的一般形式,根据已有试验资料关于普通混凝土、再生骨料混凝土、轻骨料混凝土和各向同性岩石破坏包络面的特征,建议考虑Lode角和静水压力对受压损伤比影响以及考虑材料类型对受拉损伤比影响的六参数损伤比变量表达式,且损伤...     

Periodic Exposure of Plasma-Activated Medium Alters Fibroblast Cellular Homoeostasis

Excess amounts of redox stress and failure to regulate homeostatic levels of reactive species are associated with several skin pathophysiologic conditions. Nonmalignant cells are assumed to cope better with higher reactive oxygen and nitrogen species (RONS) levels. However, the effect of periodic stress on this balance has not been investigated in fibroblasts in the field of plasma medicine. In this study, we aimed to investigate intrinsic changes with respect to cellular proliferation, cell cycle, and ability to neutralize the redox stress inside fibroblast cells following periodic redox stress in vitro. Soft jet plasma with air as feeding gas was used to generate plasma-activated medium (PAM) for inducing redox stress conditions. We assessed cellular viability, energetics, and cell cycle machinery under oxidative stress conditions at weeks 3, 6, 9, and 12. Fibroblasts retained their usual physiological properties until 6 weeks. Fibroblasts failed to overcome the redox stress induced by periodic PAM exposure after 6 weeks, indicating its threshold potential. Periodic stress above the threshold level led to alterations in fibroblast cellular processes. These include consistent increases in apoptosis, while RONS accumulation and cell cycle arrest were observed at the final stages. Currently, the use of NTP in clinical settings is limited due to a lack of knowledge about fibroblasts’ behavior in wound healing, scar formation, and other fibrotic disorders. Understanding fibroblasts’ physiology could help to utilize nonthermal plasma in redox-related skin diseases. Furthermore, these results provide new information about the threshold capacity of fibroblasts and an insight into the adaptation mechanism against periodic oxidative stress conditions in fibroblasts.     

Combined Treatment with Cryptocaryone and Ultraviolet C Promotes Antiproliferation and Apoptosis of Oral Cancer Cells

Cryptocaryone (CPC) was previously reported as preferential for killing natural products in oral cancer cells. However, its radiosensitizing potential combined with ultraviolet C (UVC) cell killing of oral cancer cells remains unclear. This study evaluates the combined anti-proliferation effect and clarifies the mechanism of combined UVC/CPC effects on oral cancer cells. UVC/CPC shows higher anti-proliferation than individual and control treatments in a low cytotoxic environment on normal oral cells. Mechanistically, combined UVC/CPC generates high levels of reactive oxygen species and induces mitochondrial dysfunction by generating mitochondrial superoxide, increasing mitochondrial mass and causing the potential destruction of the mitochondrial membrane compared to individual treatments. Moreover, combined UVC/CPC causes higher G2/M arrest and triggers apoptosis, with greater evidence of cell cycle disturbance, annexin V, pancaspase, caspases 3/7 expression or activity in oral cancer cells than individual treatments. Western blotting further indicates that UVC/CPC induces overexpression for cleaved types of poly (ADP-ribose) polymerase and caspase 3 more than individual treatments. Additionally, UVC/CPC highly induces γH2AX and 8-hydroxy-2’-deoxyguanosine adducts as DNA damage in oral cancer cells. Taken together, CPC shows a radiosensitizing anti-proliferation effect on UVC irradiated oral cancer cells with combined effects through oxidative stress, apoptosis and DNA damage.     

利用粘土电解膨效应改善油藏渗透特性

为了在修复粘土伤害、改善油藏渗透特性中应用直流电场,用粘土膨胀实验及填砂岩心渗流实验研究了直流电场作用下蒙脱石、高岭石、伊利石的电解膨效应及含蒙脱石的石英砂填砂岩心的渗透率变化规律。实验结果表明,粘土的膨胀性越强,其电解膨效应越明显;粘土电解膨率随着电场强度E的增加而增加,E>2V/m后趋于稳定;外加直流电场能够提高填砂岩心的渗透率,渗透率因子随E的增加而增加,E>12V/m时其增幅较小。利用外加直流电场下粘土的电解膨效应可以修复或者防止粘土的膨胀伤害、改善油藏渗透特性,该方法对于膨胀性粘土含量高、粘土膨胀伤害严重的油藏效果更明显。     

一种基于塑料光纤的计算机网络的研制与开发

提出一种基于塑料光纤(POF)传输媒质的计算机网络.该网络由个人计算机、光发射/接收单元和650nm的POF组成,光发射/接收模块用Agilent公司生产的HFBR-1505/2505A.为满足数字光纤通信系统对线路编码的要求,采用传号反转码并由光收发单元实现码型变换.研究结果表明,该网络具有高带宽、高可靠性的特点.通过编写的Visual C 网络语音电话程序,验证了该方案的有效性和可行性.     

某机场候机楼静力弹塑性分析

对某高安全等级、大柱距机场候机楼的结构形式给予介绍。为保证结构在罕遇地震下不倒,结构设计时在常规分析的基础上采用了静力弹塑性分析方法进行罕遇地震作用下的抗震分析。     

载荷作用下聚碳酸酯试件温升的实验研究

描述了红外辐射技术和热电偶用于测量聚合物材料变形时表面和内部温度的方法,在动态压缩中,用T型微丝热电偶测得了聚碳酸酯的内部温度变化;在准静态拉伸试验中,用红外热像仪获得了聚碳酸酯拉伸过程中的表面温度变化及表面温度场。结果表明,聚合物在准静态拉伸过程中,接近材料的屈服点时温度开始上升,在屈服点处试件表面温度最高,表面温度上升23℃至26℃,达到最高温度的时间与应变率有关;动态压缩时,试件中心温度上升最高,由里向外逐渐降低,试件内部温度与应变率和离表面的距离有关,在应变率为2500 s-1时,内部温度上升约42℃,有60%的塑性功转化为热。     

Evolution of Quasicrystals and Long-Period Stacking Ordered Structures During Severe Plastic Deformation and Mixing of Dissimilar Mg Alloys Upon Friction Stir Welding

Microstructural evolution during severe plastic deformation and mixing of Mg_(95.8)Zn_(3.6)Gd_(0.6) and Mg_(97)Cu_1Y_2(at%) alloys upon friction stir welding was studied.A laminated onion-ring structure composed of alternative distribution of layers with significantly refined microstructures from diff erent alloys was formed in the stirred zone.Coarse quasicrystals were broken up and dispersed with most of them being transformed into cubic W-phase particles,and thick 18 R long-period stacking ordered plates were fractured and transformed into fine 14 H-LPSO lamellae in the stirred zone(SZ) experiencing complex material flow under high strain rate.Fine W-phase particles and 14 H-LPSO lamellae formed during dissimilar friction stir welding(FSW) usually have no specific orientation relationship with surrounding Mg matrix.Chemical measurements demonstrated occurrence of interdiff usion between dissimilar layers in the SZ.Phase transformation was observed for some particles of quasicrystals and long-period stacking ordered(LPSO) in regions slightly outside the SZ.An ultimate tensile strength of ～ 415 MPa and an elongation to failure of ～ 27.8%,both exceeding those of base materials,were obtained in the SZ,due to microstructural refinement and formation of a laminated structure.     

塑料包装材料化学物向食品迁移的模型研究进展

塑料包装材料内含化学物向食品的迁移会造成食品污染并最终危害消费者的健康,近年来受到国内外广泛关注.30多年来,美国食品与药品管理局(FDA)和欧盟委员会(EC)开展了大量包装材料化学物迁移相关的理论与实验研究.由于迁移实验复杂、费用昂贵、要求先进的分析测试仪器,在一般实验室很难开展,因此近年来各国开始关注迁移理论预测的研究.文中介绍了塑料包装材料化学物迁移数学解析模型的研究进展,应用无量纲化方法对比分析了模型参数对各模型的影响.