Advance application of Raman spectroscopy for quantitative analysis of noncrystalline components in thin films of poly(ε-caprolactone)/poly(butadiene) blends

A quantitative analysis method for the distribution of noncrystalline poly(butadiene) component in poly(ε-caprolactone)/poly(butadiene) (PCL/PB) binary blends have been analyzed by advance application of Raman spectroscopy, optical microscopy, and differential scanning calorimetry (DSC) techniques. Thin films of different compositions of PCL/PB binary blends were prepared from solution and isothermally crystallized at a certain temperature. After calibration with real data, quantitative analyses by Raman spectroscopy revealed the amorphous PB are trapped inside the PCL crystals. Polarized optical microscopy and real time atomic force microscopy were used to collect data for the crystal morphology and crystal growth rate. For pure PCL crystals, a morphology of truncated lozenge shape was observed, independent of crystallization temperature and regardless of the blends compositions. For the pure PCL and their blends, almost unique crystal growth rate was found. The miscibility behaviors using DSC were drawn through melting point depression method. The Hoffman-Weeks extrapolations of the blends were found to be linear and identical with those of the neat PCL. The interaction parameter for the blends indicating that the PCL and PB blends have no intermolecular interaction, confirming the blends are immiscible. Despite the immiscibility of the blend, the PCL crystals do not bend during the growth process and do not reduce the growth rate as they do for miscible blend systems.     

The Role of Testosterone in the Elderly: What Do We Know?

Testosterone is the most important hormone in male health. Aging is characterized by testosterone deficiency due to decreasing testosterone levels associated with low testicular production, genetic factors, adiposity, and illness. Low testosterone levels in men are associated with sexual dysfunction (low sexual desire, erectile dysfunction), reduced skeletal muscle mass and strength, decreased bone mineral density, increased cardiovascular risk and alterations of the glycometabolic profile. Testosterone replacement therapy (TRT) shows several therapeutic effects while maintaining a good safety profile in hypogonadal men. TRT restores normal levels of serum testosterone in men, increasing libido and energy level and producing beneficial effects on bone density, strength and muscle as well as yielding cardioprotective effects. Nevertheless, TRT could be contraindicated in men with untreated prostate cancer, although poor findings are reported in the literature. In addition, different potential side effects, such as polycythemia, cardiac events and obstructive sleep apnea, should be monitored. The aim of our review is to provide an updated background regarding the pros and cons of TRT, evaluating its role and its clinical applicability in different domains.     

4－氨基－3－苯基丁酸的合成方法

对已知的涉及合成4－氨基－3－苯基丁酸的方法进行了分类、总结,包括涉及硝基苯乙烯的Michael加成反应、以苯基戊二酸为中间体的反应、通过还原氰基或硝基的反应等,从反应原料、反应步骤、产率等方面分析了不同方法的利弊,其中,以糠氯酸为原料的方法最为新颖。为后续工作者在现有成果的基础上进行更深入的研究,寻求更为适用的合成方法提供方便。     

辽河西部凹陷稠油油藏特征及其成因探讨

辽河油田西部凹陷稠油资源丰富,分布广泛,类型多样,地化特征显著。根据原油的成熟度、生物降解程度及生物降解后油气的注入情况等多元因素,将该区稠油划分为原生稠油、降解型稠油及降解—混合型稠油。西部凹陷稠油成因主要为生物降解作用,水洗作用和氧化作用则促进了原油稠化,而温度、地下水、化学条件及构造条件等是控制原油降解程度的主要因素。     

心理护理临床路径对显微血管减压术后功能延迟恢复患者的影响

目的探讨心理护理临床路径对显微血管减压术后神经功能延迟恢复患者的影响。方法将40例行显微血管减压术术后发生延迟恢复的患者按随机数字表法分为2组：观察组和对照组,每组20例。2组患者均采用常规治疗及常规护理。在此基础上,观察组实施心理护理临床路径。不同入院时间（入院时、入院后3 d、入院后1周）观察组实施心理护理临床路径采用90项症状自评量表（SCL-90）进行评分,采用SCL-90对观察组、对照组入院后1周进行评分,采用Zung抑郁自评量表（SDS）、焦虑自评量表（SAS）对观察组、对照组入院时、入院后1周进行评分。结果入院后1周观察组实施心理护理临床路径SCL-90评分值显著低于入院时及入院后3 d（P〈0.01）。观察组入院后1周躯体化、强迫症状、人际关系敏感、抑郁、焦虑、偏执SCL-90评分值均明显低于对照组（P〈0.05或P〈0.01）,观察组入院后1周敌对、恐怖SCL-90评分值与对照组比较差异均无统计学意义（均P〉0.05）。观察组入院后1周SDS、SAS评分值均明显低于对照组（均P〈0.01）,观察组入院后1周SDS、SAS评分值均明显低于入院时（均P〈0.01）。结论心理护理临床路径能有效地降低显微血管减压术后功能延迟恢复患者的焦虑、抑郁程度,改善了人际关系,促进患者神经功能的恢复。     

三塘湖盆地马朗凹陷地层—岩性油气藏勘探实践与认识

通过回顾三塘湖盆地马朗凹陷侏罗系地层—岩性油气藏的勘探历程,系统总结了实践中的关键环节和获得的地质认识。在沉积体系精细研究的基础上,强化老井复查和油藏认识,发现马朗凹陷侏罗系大型地层-岩性油藏,并不断扩展勘探层系。高分辨率层序地层学等技术是勘探取得突破的根本保证,油层压裂改造技术可有效促进预探发现,超前注水增压、压裂投产技术实现有效开发。分析了该油气藏的形成条件和潜力。芦草沟组优质烃源岩控制其分布范围,勘探前景良好;北部地层抬升与南部物源砂体匹配形成岩性圈闭;晚燕山期—喜山期构造运动促成了油气的高效运聚。     

台北凹陷异常高压形成机理探讨

在系统总结沉积盆地中异常高压形成机制的基础上,以台北凹陷为实例进行研究,表明:沉积盆地中形成异常高压的机制虽多,但对盆地大规模异常地层压力形成有决定作用的地质作用主要有欠压实作用、烃类生成作用和构造作用。     

辽河东部凹陷南段沙三上亚段沉积特征与聚煤规律

根据单井岩性、沉积构造、测井以及连井剖面,对东部凹陷南段沙三上亚段进行了沉积环境和聚煤规律分析,认为：沉积环境主要为冲积扇、曲流河、辫状河、三角洲、洪泛平原、滨浅湖以及半深湖。研究发现,研究区沙三上亚段聚煤环境类型多样,目前已发现8个聚煤区：缓坡带的桃园三角洲聚煤区、黄金带辫状河聚煤区、热河台辫状河聚煤区、桃园废弃河道聚煤区、于楼废弃河道聚煤区、热河台废弃河道聚煤区,中间洼陷带的荣兴屯聚煤区、小龙湾聚煤区,聚煤区沿低洼地带呈长轴展布。煤层主要发育于辫状河泛滥平原、曲流河废弃河道、三角洲平原以及滨湖沼泽环境中,其中,辫状河泛滥平原、三角洲平原以及滨湖沼泽环境形成的煤层分布范围较广,为煤型气有利勘探区。     

浮选分级—抑制及再活化硫化矿混合精矿的分离浮选研究

对从苏州高岭土尾矿中用浮选法得到的硫化矿混合精矿进行了硫及铅锌混合精矿的分离浮选试验研究。在不磨矿的条件下,采用浮选分级-抑制及再活化浮选方法获得了铅、锌品位分别为19.95%、30.1%,回收率分别为82.00%、81.29%的铅锌混合精矿和硫品位和回收率分别为52.49%、75.5%的硫精矿。     

基于HFD和LZC特征联合的单通道静息态脑电抑郁症识别研究

目前抑郁症的临床诊断多以医生经验和患者主观感受为主,主观性强、准确率低、耗时长。随着神经电生理学和计算机技术的发展,抑郁症的客观分类与识别成为可能。但是,已有的基于静息态脑电信号的抑郁症分类识别方法较为单一,脑电特征选取的精准性、综合性和有效性有待进一步探究。本文在设计包含两种模态实验范式的基础上,提出一种基于HFD和LZC特征联合的单通道静息态脑电抑郁症分类识别方法,以期用较少的特征获得较高的分类准确率。首先采集8名抑郁患者和8名健康对照的静息态脑电信号;然后提取其非线性动力学特征参数HFD和LZC;最后将特征数据输入到非线性支持向量机模型中进行分类识别。结果表明,联合特征得到的灵敏度、特异性和分类正确率最高分别为98.12%、96.67%和95.10%,较单独HFD/LZC特征平均分别提高了23.05%、17.02%和19.29%。同时,模型主体部分仅耗时约12 s。研究结果对临床实践中抑郁症的识别和辅助诊断具有重要意义。