Antiviral activity and mechanism of action of novel thiourea containing chiral phosphonate on tobacco mosaic virus

Using half-leaf method O,O'-diisopropyl (3-(L-1-(benzylamino)-1-oxo-3- phenylpropan-2-yl)thioureido)(phenyl)methyl phosphonate (2009104) was studied for its activity on tobacco mosaic virus (TMV). It showed good curative activity in vivo and the curative activity at 500 μg/mL was found to be 53.3%. In vivo treatment with the control agent Ningnanmycin at 500 μg/mL resulted in 51.2% inhibition and curative inhibition rates respectively. Dot-ELISA test was employed to verify the efficacy of activity of compound 200910 for anti-TMV activity. The mechanism of action of compound 2009104 to resist TMV was also studied. The results showed that the resistance enzymes PAL, POD, SOD activity and chlorophyll content after TMV inoculation K(326) (Nicotiana tabacum K(326)) of tobacco plants followed by treatment with compound 2009104 were significantly enhanced. The study of the effect of compound 2009104 on TMV capsid protein (CP) showed that it inhibited the polymerization process of TMV-CP in vitro.     

Adsorption of selenite and selenate ions onto thiourea‐formaldehyde resin

In the present work, thiourea‐formaldehyde (TUF) chelating resin was synthesized and used in the adsorptions of selenite (SeO) and selenate (SeO) ions. The effects of initial acidity and initial selenium concentrations on the adsorptions were examined by batch technique. The synthesized resin was applied to the elemental analysis to determine its composition. FT‐IR spectra and SEM/EDS were also recorded before and after selenite adsorption. It was found that selenite and selenate ions were adsorbed onto TUF resin at strong acidic conditions (3–5M HCl). The adsorption capacities of the resin were calculated as 833.3 mg g^?1 TUF resin for selenite ions and 526.3 mg g^?1 TUF resin for selenate. All the adsorption data obtained for both selenite and selenate ions fitted well to the Langmuir isotherm. It was seen that the adsorption mechanisms in the both adsorptions were governed by the reduction of selenite or selenate to elemental selenium, Se⁰. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011.     

Selective separation and concentration of Pd(II) from Fe(III), Co(II), Ni(II), and Cu(II) ions using thiourea‐formaldehyde resin

Thiourea‐formaldehyde (TUF), a well‐known chelating resin, has been synthesized and it was used in the adsorption, selective separation, and concentration of Pd(II) ions from Fe(III), Co(II) Ni(II), and Cu(II) base metal ions. The composition of the synthesized resin was determined by elemental analysis. The effect of initial acidity/pH and the adsorption capacity for Pd(II) ions were studied by batch technique. The adsorption and separation of Pd(II) were then examined by column technique. FTIR spectra and SEM/EDS analysis were also recorded before and after the adsorption of Pd(II). The optimum pH was found to be 4 for the adsorption. The adsorption data fitted well to the Langmuir isotherm. The maximum adsorption capacity of the TUF resin for Pd(II) ions was found to be 31.85 mg g⁻¹ (0.300 mmol g⁻¹). Chelating mechanism was effective in the adsorption. Pd(II) ions could be separated efficiently from Fe(III), Cu(II), Ni(II), and Co(II) ions using TUF resin. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011     

添加硫脲的稀土热稳定剂性能的研究

以硫脲、稀土镧为主要原料,制备了新型的稀土复合热稳定剂,并利用稀土热稳定剂与其他热稳定剂之间的协同效应,使它们按一定比例配合使用,以达到延长稳定时间的目的。实验结果表明,添加硫脲的稀土复合热稳定剂与传统热稳定稳定剂相比可以更显著地提高PVC的热稳定性能。将其与Zn（C17 H35 COO）2和Ca（C17H35COO）2按一定比例配合后,其热稳定效果更佳。     

高效液相色谱法测定二苯硫脲含量

建立了外标法分析对称二苯硫脲含量的高效液相色谱分析方法。色谱柱为菲罗门Hydro-RP柱（250 mm×4.6 mm,4μm）;流动相为甲醇-水混合溶液;检测波长：272 nm;流速：0.8 mL/min;进样量：20μL,保留时间约8.0 min。利用该方法对二苯硫脲进行分析,线性关系良好,相关系数为0.9998,相对标准偏差为1.9%,回收率为99.58%～101.23%,最小检出限14 ng。该方法具有快速、准确、简便等特点。     

硫脲对铁矿石烧结过程中二恶英的抑制作用

为实现铁矿石烧结过程二恶英(PCDD/Fs)高效低成本的控制技术,研究了硫脲对PCDD/Fs的抑制作用。硫脲添加量分别为0.05%、0.1%、0.5%时,PCDD/Fs排放浓度及毒性当量(TEQ)比未添加硫脲时(20.70ng/kg,0.272 ng TEQ/kg)分别减少了38.84%(67.63%)、47.83%(72.61%)、77.58%(76.46%),添加量为0.5%时减排率最大。硫脲加入烧结料前后,PCDD/Fs的排放始终以PCDFs为主,硫脲的抑制作用主要体现在对"从头合成"反应的抑制。TEQ最大贡献物始终是23478-P5CDF。     

银精矿在[Bmim]HSO_4离子液体—硫脲体系中的浸出行为

用[Bmim]HSO4离子液体取代硫酸进行了硫脲浸取银精矿的浸出行为研究。考察了磨矿细度、[Bmim]HSO4浓度、硫脲浓度、Fe3+浓度、液固比、浸出时间等对银浸出率的影响。结果表明,在磨矿细度-0.043mm占80%、硫脲浓度0.18mol/L、[Bmim]HSO4浓度0.3mol/L、Fe3+浓度7.5mmol/L、液固比3∶1、浸出时间18h的最优条件下,银浸出率可达到73.96%。在[Bmim]HSO4-硫脲、H2SO4—硫脲和氰化体系中,[Bmim]HSO4—硫脲体系不但银浸出率最高,而且浸出时间最短。     

Influence of Growth Conditions on Magnetite Nanoparticles Electro-Crystallized in the Presence of Organic Molecules

Magnetite nanoparticles were synthesized by electrocrystallization in the presence of thiourea or sodium butanoate as an organic stabilizer. The synthesis was performed in a thermostatic electrochemical cell containing two iron electrodes with an aqueous solution of sodium sulfate as electrolyte. The effects of organic concentration, applied potential and growth temperature on particle size, morphology, structure and magnetic properties were investigated. The magnetite nanoparticles were characterized by X-ray diffraction, electron microscopy, magnetometry and Mössbauer spectrometry. When the synthesis is performed in the presence of sodium butanoate at 60 °C, a paramagnetic ferric salt is obtained as a second phase; it is possible to avoid formation of this phase, increase the specific magnetization and improve the structure of the oxide particles by tuning the growth conditions. Room-temperature magnetization values range from 45 to 90 Am²kg⁻¹, depending on the particle size, type of surfactant and synthesis conditions. Mössbauer spectra, which were recorded at 290 K for all the samples, are typical of nonstoichiometric Fe_3−δO₄, with a small excess of Fe³⁺, 0.05 ≤ δ ≤ 0.15.     

脒基硫脲对酸性硫酸盐溶液中铜电沉积过程影响的研究

研究添加剂对电沉积的作用机理及添加剂用量对镀层结构的影响,有利于开发一种更好效果的添加剂。为了获得良好的镀层,硫脲及其衍生物作为添加剂已经广泛应用于电镀工业中,脒基硫脲(GTU)作为电镀添加剂,采用循环伏安法(CV)和电化学石英晶体微天平(EQCM)技术,考察GTU在酸性溶液中对铜沉积机理的影响。CV结果表明,脒基硫脲对铜电沉积有抑制作用;QCM分析表明,当镀液中含有GTU时,铜阴极沉积和阳极溶出过程的M/n分别为61.50,64.12 g/mol,表明电极反应过程中,Pt/Cu电极表面的铜离子沉积从二电子过程过渡到单电子过程,添加剂的最佳浓度为10 mmol/L。