大陡山露天爆破参数及网路优化

笔者通过近几年35次爆破参数及起爆网路优化对比试验，逐步优化了适合大陡山露天采场矿岩性质的各种爆破参数及起爆网路，主要爆破技术指标和爆破器材消耗均取得了较好效果。     

传输孔射负压多级起爆技术在吉林油田的应用

详细介绍了传输射孔负压多级起爆（TCP）技术在地质，工程方面的优势，介绍了该项技术的主要特点及应用实例，负压多级压力起爆需要由开孔装置，点火装置，延时装置，减震系统，压力转换装置，P－T卡瓦式可回收封隔器等部分组成，负压开孔装置是整个技术的核心部分，起到延迟起爆器受压启动之后继续接受环空压力，完成剪断剪切销及活塞上行等工作，剪切销切值的选择及延迟起爆管的延时精确性都是该项技术应用成功与否的关键。     

氯化苯生产中氯化尾气爆鸣事故的原因和预防措施

分析了氯化苯生产过程中爆鸣事故产生的原因,提出了预防措施。     

动态光弹性应用的初步研究

爆破与高速冲去载荷所产生的应力波在弹性结构物中的传播,在理论分析上极为困难,但这类问题可以用动态光弹性法进行分析。本文仅涉及地震波传播及爆破方法选择两个课题,研究表明:在这类课题中,利用动态光弹性法有其优越性。     

柔性导爆索输出性能测试及传爆规律

为了进一步简化弹药结构,提高武器系统安全性和可靠性,对影响柔性导爆索多点同步起爆网络输出性能的主要参数——爆速和爆压进行了研究。利用探针法,采用时间间隔测试仪对柔性导爆索爆速进行测试,探讨了靶距对爆速测试结果的影响,结果发现,影响柔性导爆索爆速的主要因素是装药密度、约束强度和装药直径,在同样条件下,银导爆索比铅导爆索的爆速明显提高。研究了微型H型锰铜压力计测试导爆索爆压的方法,结果表明,只有极小尺寸下爆压变化与约束材料有关,利用这些结果,能更精确地设计柔性爆炸网络。     

油气井用导爆索收缩性测试技术

为在高温环境中安全准确地测量导爆索长度的微量变化,研制了安全防爆的导爆索收缩性测试台架.此台架由导爆索安装装置、温度控制系统、防爆壳体、位移测量系统、无震动工作台面以及数据采集与处理系统组成.其加温过程采用6点PID自动温度控制;其长度测量采用互感式位移传感器,位移分辨率为0.1 μm或0.2 μm.该台架能满足产品标准对测试的要求.     

导弹弹头引控系统的地测设备故障诊断专家系统

导弹弹头引控系统的地测设备故障诊断专家系统由地测微机、采集控制器、头部监控装置组成,并通过I/O总线和专用总线接口相连.系统硬件实时采集和检测弹头引控系统地面测试设备的模拟量、数字量和时序量等测试信号,与计算机间通过串行通讯,给专家系统提供实时采集信息.软件功能包括知识获取及推理.     

Relationships between Intraocular Pressure,Effective Filtration Area,and Morphological Changes in the Trabecular Meshwork of Steroid-Induced Ocular Hypertensive Mouse Eyes

We investigated whether an inverse relationship exists between intraocular pressure (IOP) and effective filtration area (EFA) in the trabecular meshwork (TM) in a steroid-induced ocular hypertensive (SIOH) mouse model and the morphological changes associated with the reduction of EFA. C57BL/6 mice (n = 15 per group) received either 0.1% dexamethasone (DEX) or saline eye drops twice daily for five weeks. IOP was measured weekly. Fluorescent tracers were injected into the anterior chamber to label EFA at the endpoint. Injected eyes were fixed and processed for confocal microscopy. EFA in the TM was analyzed. Light and electron microscopy were performed in high- and low-tracer regions of six eyes per group. The mean IOP was ~4 mm Hg higher in DEX-treated than saline-treated control eyes (p < 0.001) at the endpoint. EFA was reduced in DEX-treated eyes compared to controls (p < 0.01) and negatively correlated with IOP (R² = 0.38, p = 0.002). Reduced thickness of juxtacanalicular tissue (JCT) and increased abnormal extracellular matrix in the JCT were found to be associated with reduced EFA. Our data confirm the inverse relationship between EFA and IOP, suggesting that morphological changes in the JCT contribute to the reduction of EFA, thus elevating IOP in SIOH mouse eyes.     

提高煤矿许用无起爆药电雷管起爆能力的研究

飞片式无起爆药电雷管在矿山使用中经常出现不能引爆三级煤矿许用乳化炸药的问题。试验证明,飞片式无起爆药电雷管铅板穿孔值约为10 mm,虽然大于8~#有起爆药电雷管的铅板穿孔值(约为9 mm),但实际起爆能力低于8~#有起爆药电雷管,甚至低于6~#有起爆药电雷管。对此,笔者利用加大飞片式无起爆药雷管管壳直径和增加底部装药量的设计,解决了这一难题。     

An Innovative In Vitro Open-Angle Glaucoma Model (IVOM) Shows Changes Induced by Increased Ocular Pressure and Oxidative Stress

Primary Open-Angle Glaucoma (POAG) is a neurodegenerative disease, and its clinical outcomes lead to visual field constriction and blindness. POAG’s etiology is very complex and its pathogenesis is mainly explained through both mechanical and vascular theories. The trabecular meshwork (TM), the most sensitive tissue of the eye anterior segment to oxidative stress (OS), is the main tissue involved in early-stage POAG, characterized by an increase in pressure. Preclinical assessments of neuroprotective drugs on animal models have not always shown correspondence with human clinical studies. In addition, intra-ocular pressure management after a glaucoma diagnosis does not always prevent blindness. Recently, we have been developing an innovative in vitro 3Dadvanced human trabecular cell model on a millifluidicplatform as a tool to improve glaucoma studies. Herein, we analyze the effects of prolonged increased pressure alone and, in association with OS, on such in vitro platform. Moreover, we verify whethersuch damaged TM triggers apoptosis on neuron-like cells. The preliminary results show that TM cells are less sensitive to pressure elevation than OS, and OS-damaging effects were worsened by the pressure increase. The stressed TM releases harmful signals, which increase apoptosis stimuli on neuron-like cells, suggesting its pivotal role in the glaucoma cascade.