Histamine determination in tears as an index of safety in use of cosmetic products

To assess ocular irritancy caused by chemical and cosmetic products a reliable method based on evaluation of histamine (Hm) in tears is presented. Hm is measured at picomole levels by HPLC and fluorimetric detection after fluorescamine-HM derivatization. In order to avoid any uncontrolled irritation and stimulation of the conjunctiva during sample collection, a procedure of conjunctiva lavage was developed. A balanced salt solution (50 μl) containing a known amount of Hm-fluorophore as reference standard is instilled in the conjunctiva fornix. After a few seconds 20 μl of tear fluid is collected: 10 μl are immediately analysed and 10 μl after derivatization reaction. In this way it is possible to evaluate tear dilution and to assess Hm content in less than 10 minutes.
In a group of 20 normal subjects Hm has been determined in comparison with that of two volunteers after topical application of 50 μ of 0.2% and 0.4% sodium lauryl sulphate solution. A contact of 30 seconds of the cosmetic ingredient caused an immediate dose-dependent Hm release through a direct cytotoxic damage of cell membranes due to the surfactant action.
Évaluation de l'irritation occulaire due aux cosmétiques par la détermination de l'histamine lacrimale     

A new method of characterization for stratified thermal energy stores

A new method for characterization of stratified thermal energy stores (TES) that integrates both the first law and the second law concerns is presented here. The first law concern is incorporated into a quantity called energy response factor and the second law concern into an entropy generation ratio. A product of these two quantities is at the heart of the TES efficiency definitions. This approach removes the overemphasis of the existing methods either on the first or the second law of thermodynamics which often biases the characterization results. The information about the evolution of the temperature field of the system in time is the prerequisite of the new method. It may be obtained from experiments or from suitable numerical simulations. The current method can be easily integrated into computational fluid dynamic (CFD) simulations and thus facilitate CFD-based design analysis. As an example of such CFD-integrated analysis, a large-scale hot water seasonal heat store is numerically studied to identify the effects of aspect ratio, containment shape, internal structures, and containment size on their efficiency. The results suggest the effectiveness of the new method in deriving useful design insights.     

大庆庆深气田深井快速钻井技术

为加快庆深气田深层天然气勘探开发步伐,进行了钻头选型、复合钻进、井身质量控制、井下复杂情况预防和气体钻井等深井快速技术研究与现场试验,深井机械钻速提高了23.1%,钻井周期缩短了58 d。详细介绍了庆深气田深井快速钻井技术和现场试验情况,并分析了试验效果,对庆深气田深井钻井提出了开展钻头选型试验、完善钻头序列,研制适应硬地层的牙轮钻头,研究营城组地层防塌技术和抗220℃高温水基钻井液体系及水泥浆体系的建议。     

康山金矿地质地球化学特征及其成因

康山金矿产在豫西熊耳山古隆起区的结晶基底太华群和盖层中元古界熊耳群地层接触界面附近，矿体严格受构造破碎蚀变带控制。流体包裹体，稳定同位素等研究表明，成矿物质来自太华群变质岩，成矿流体的性质与变质热液截然不同，而与花岗岩浆热液相近似。该矿床的形成与燕山期发生的同构造－花岗岩浆期热液活动有关，金沉淀成矿阶段有大气水的混入。     

高能气体压裂联作技术进展

国内高能气体压裂增产技术已经由单一的有壳弹、无壳弹、液体药、可控脉冲等高能气体压裂,进展到与射孔、水力压裂、酸化、化学解堵等技术相联作的综合压裂阶段。分别对高能气体压裂与射孔、水力压裂和化学解堵等联作技术的基本原理、现场试验、作业效果等进行了介绍。高能气体压裂已发展成一种基本成熟的、综合性油气田增产改造新技术。     

钻井液与油气层损害及保护室内研究中的数学方法

介绍了在钻井液与油气层损害及保护研究领域里常用的数种具有推广应用价值的数学方法，说明了各种方法的基本原理及其在此研究领域中的具体应用成果。     

Rapid analysis of polymer homologues and additives with SFE/SFC-MS coupling

A rapid and easy analysis method for polymers is presented. The method involves sample preparation by SFE, separation of the extracted compounds by SFC and simultaneous quantitative detection by FID, as well as identification of unknowns by MS. The applications illustrate how structural research work and routine polymer analysis can be done with this time saving method.     

Thermal Diffusivity in Supercritical Fluids Measured by Thermal Lensing

Thermal diffusivities of supercritical CO₂ and C₂H₆ were determined over a wide density range with a photothermal technique. The thermal lens, formed by the degradation of the absorbed light energy as heat by the sample, allows the employment of a nonequilibrium method in the critical region. Controlling the refractive-index gradient, i.e., a density gradient, perturbations can be maintained at levels where convection is negligible. An easy-to-operate setup allowed us to measure thermal diffusivities in the density ranges 5 to 20 mol·dm^–3 for CO₂ at 308 and 313 K and 2 to 12 mol·dm^–3 for C₂H₆ at 308 K with a standard precision of 15%.     

硫酸生产中内喷文氏管的设计

从分析内喷文氏管喷头旋流特征入手 ,建立有关数学模型或表达式 ,提出对内喷文氏管喷头、收缩管支管内径、喷嘴与喉管距离进行设计的方法 ,并对设计中值得注意的问题进行理论和实践上的讨论。     

Development of an integrated model for airflow in building spaces

In building energy simulation, an integrated modelling of airflow in the building needed. Therefore, in this paper two approaches are used for building energy simulation: zonal network for modelling of the building segments and Computational Fluid Dynamics (CFD) for modelling of the airflow. It is noted that a synchronize solution process is needed for the building and the CFD equation-sets. For this purpose an iterative procedure is used to corresponding solution of these equations.